PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis

Family

C2H2

Protein Properties

Length: 454aa MW: 49938.8 Da PI: 6.9308

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Ahy#S59559066	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.4	0.00022	108	130	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+Cp Cg sF++ ++ H t+ Ahy015081 108 YECPVCGNSFRSEDEVSEHVDTC 130 99****************99887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.10.20.90	5.8E-9	24	52	No hit	No description
PROSITE profile	PS50157	10.492	108	138	IPR007087	Zinc finger, C2H2
CDD	cd09212	2.40E-18	163	252	No hit	No description
SuperFamily	SSF143503	3.92E-17	165	253	IPR018997	PUB domain
Pfam	PF09409	6.2E-16	168	243	IPR018997	PUB domain
SMART	SM00580	3.5E-14	169	236	IPR018997	PUB domain
SuperFamily	SSF54236	5.17E-14	314	427	IPR029071	Ubiquitin-related domain
Gene3D	G3DSA:3.10.20.90	5.8E-9	331	425	No hit	No description
PROSITE profile	PS50033	11.785	343	427	IPR001012	UBX domain
Pfam	PF00789	2.3E-5	343	423	IPR001012	UBX domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005515	Molecular Function	protein binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 454 aa Download sequence Send to blast
MDDVKDKMKG FMKKVNNSFT SSSSAKFKGQ GRVLGSSSSP SPPPYATANS TSTPRPRPLN 60 SNPTPPPHKA TASSAERDPK PPTSGFDPFD SFVTSSKRSQ NGYSLNVYEC PVCGNSFRSE 120 DEVSEHVDTC LSNNGERADV SQLADTGADS NAELEVCVGT YVSGKPSHGS IDILLKLLKN 180 VVREPENAKF RKIRLANPKI KEAIAEVIGG TELICFLGFE LKDENGETWA VMELPSEEQI 240 RLINKATLLL ESQQVSPKSE NLAAASADNI DAKPESKPID RQVKVFFAVP ETVAAKIELP 300 DSFYKLSVEE VRREAELRRK KIEESQLLIP KSLKEKQAKA AKKRYTKAII RVQFPDGVVL 360 QGVFSPWEPT MALYEFVSSA LKQPGLEFEL MHPVVVRRQA IPRFAKAGEN SKTLEDEDLV 420 PSALIKFKPL ETDSVVFTGL KNELLQISEP LVNA

Sequence ? help Back to Top

Protein Sequence Length: 454 aa Download sequence Send to blast

MDDVKDKMKG FMKKVNNSFT SSSSAKFKGQ GRVLGSSSSP SPPPYATANS TSTPRPRPLN  60
SNPTPPPHKA TASSAERDPK PPTSGFDPFD SFVTSSKRSQ NGYSLNVYEC PVCGNSFRSE  120
DEVSEHVDTC LSNNGERADV SQLADTGADS NAELEVCVGT YVSGKPSHGS IDILLKLLKN  180
VVREPENAKF RKIRLANPKI KEAIAEVIGG TELICFLGFE LKDENGETWA VMELPSEEQI  240
RLINKATLLL ESQQVSPKSE NLAAASADNI DAKPESKPID RQVKVFFAVP ETVAAKIELP  300
DSFYKLSVEE VRREAELRRK KIEESQLLIP KSLKEKQAKA AKKRYTKAII RVQFPDGVVL  360
QGVFSPWEPT MALYEFVSSA LKQPGLEFEL MHPVVVRRQA IPRFAKAGEN SKTLEDEDLV  420
PSALIKFKPL ETDSVVFTGL KNELLQISEP LVNA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifw_A	5e-16	298	427	23	146	Tether containing UBX domain for GLUT4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015957231.1	0.0	plant UBX domain-containing protein 2
Swissprot	Q9ZU93	0.0	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A444ZU93	0.0	A0A444ZU93_ARAHY; Uncharacterized protein
STRING	GLYMA08G04760.6	0.0	(Glycine max)

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]