PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn363861

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

AP2

Protein Properties

Length: 399aa MW: 43916.9 Da PI: 4.8479

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn363861	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	26.7	1.4e-08	135	178	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+++ ++gr d + k+++lg f+ta Aa+a+++a+ k++g Achn363861 135 SQYRGVTFYWRTGR------D------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 178 789*99999999......5......56**********************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	12.813	126	186	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.4E-10	135	187	IPR016177	DNA-binding domain
SMART	SM00380	4.0E-21	136	192	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.4E-11	150	186	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	11.588	175	265	IPR001471	AP2/ERF domain
SMART	SM00380	3.1E-7	217	271	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.51E-9	221	267	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	2.4E-10	232	265	IPR001471	AP2/ERF domain
CDD	cd00018	5.24E-13	232	267	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 399 aa Download sequence Send to blast
MWDLNDSPDP TTRNDESEVC SYGDDDKGKR VGSVSNSSSS AVDDEDSGGQ KRSGSKIFGF 60 SVTQPDDTYS SEPDPPVTHQ FFPSSDDGGA ANFPRAHWVG VRFSQSEGPA AAAGKFTNIT 120 QPLKKSRRGP RSRSSQYRGV TFYWRTGRDC GKQVYLGGFD TAHAAARAYD RAAIKFRGVE 180 ADINFTLEEY EEDLKQVASL ILLNYWYFSA ENSILIRNTW ADIENLVANP LYVYLGLFDT 240 EIEAARAYDK AAIKCNGKEA VTNFDPSIYE DEFNSTECSG NPSDHNLDLS LGCSASKQKS 300 RDVAADQHHT SMPFEVSDLR NHGFQPKVQC PSSSTNDNGG YLSLSTSDCQ NWQLNIINNP 360 PQVFATAAAS SGFPQQKITT TPQNWLQQNG FHFSMRPS*

Sequence ? help Back to Top

Protein Sequence Length: 399 aa Download sequence Send to blast

MWDLNDSPDP TTRNDESEVC SYGDDDKGKR VGSVSNSSSS AVDDEDSGGQ KRSGSKIFGF  60
SVTQPDDTYS SEPDPPVTHQ FFPSSDDGGA ANFPRAHWVG VRFSQSEGPA AAAGKFTNIT  120
QPLKKSRRGP RSRSSQYRGV TFYWRTGRDC GKQVYLGGFD TAHAAARAYD RAAIKFRGVE  180
ADINFTLEEY EEDLKQVASL ILLNYWYFSA ENSILIRNTW ADIENLVANP LYVYLGLFDT  240
EIEAARAYDK AAIKCNGKEA VTNFDPSIYE DEFNSTECSG NPSDHNLDLS LGCSASKQKS  300
RDVAADQHHT SMPFEVSDLR NHGFQPKVQC PSSSTNDNGG YLSLSTSDCQ NWQLNIINNP  360
PQVFATAAAS SGFPQQKITT TPQNWLQQNG FHFSMRPS*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269\|PubMed:1675158, ECO:0000269\|PubMed:23034631, ECO:0000269\|PubMed:7919989}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:12893888, ECO:0000269\|PubMed:14555699}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JN247401	0.0	JN247401.1 Actinidia deliciosa cultivar Hayward APETALA2 mRNA, complete cds, alternatively spliced.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028061695.1	1e-109	AP2-like ethylene-responsive transcription factor TOE3
Swissprot	P47927	2e-85	AP2_ARATH; Floral homeotic protein APETALA 2
TrEMBL	A0A2R6RL37	0.0	A0A2R6RL37_ACTCH; Floral homeotic protein like
STRING	cassava4.1_005852m	1e-100	(Manihot esculenta)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2019	23	65

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G36920.2	9e-82	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Thamilarasan SK,Park JI,Jung HJ,Nou IS Genome-wide analysis of the distribution of AP2/ERF transcription factors reveals duplication and CBFs genes elucidate their potential function in Brassica oleracea. BMC Genomics, 2014. 15: p. 422 [PMID:24888752] Zhang GB,Yi HY,Gong JM The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation. Plant Cell, 2014. 26(10): p. 3984-98 [PMID:25326291] Ranocha P,Francoz E,Burlat V,Dunand C Expression of PRX36, PMEI6 and SBT1.7 is controlled by complex transcription factor regulatory networks for proper seed coat mucilage extrusion. Plant Signal Behav, 2014. 9(11): p. e977734 [PMID:25531128] Djemal R,Khoudi H Isolation and molecular characterization of a novel WIN1/SHN1 ethylene-responsive transcription factor TdSHN1 from durum wheat (Triticum turgidum. L. subsp. durum). Protoplasma, 2015. 252(6): p. 1461-73 [PMID:25687296] Kazan K Diverse roles of jasmonates and ethylene in abiotic stress tolerance. Trends Plant Sci., 2015. 20(4): p. 219-29 [PMID:25731753] Prunet N, et al. SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signalling. J. Exp. Bot., 2015. 66(21): p. 6905-16 [PMID:26269626] Xie W, et al. Exploring potential new floral organ morphogenesis genes of Arabidopsis thaliana using systems biology approach. Front Plant Sci, 2015. 6: p. 829 [PMID:26528302] Zumajo-Cardona C,Pabón-Mora N Evolution of the APETALA2 Gene Lineage in Seed Plants. Mol. Biol. Evol., 2016. 33(7): p. 1818-32 [PMID:27030733] Zhao Y, et al. An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design. Sci Rep, 2016. 6: p. 23890 [PMID:27033976] Gao R,Liu P,Irwanto N,Loh R,Wong SM Upregulation of LINC-AP2 is negatively correlated with AP2 gene expression with Turnip crinkle virus infection in Arabidopsis thaliana. Plant Cell Rep., 2016. 35(11): p. 2257-2267 [PMID:27473526] Huang Z, et al. APETALA2 antagonizes the transcriptional activity of AGAMOUS in regulating floral stem cells in Arabidopsis thaliana. New Phytol., 2017. 215(3): p. 1197-1209 [PMID:27604611] Dory M, et al. Kinase-Associated Phosphoisoform Assay: a novel candidate-based method to detect specific kinase-substrate phosphorylation interactions in vivo. BMC Plant Biol., 2016. 16(1): p. 204 [PMID:27655033] Wang P, et al. Expansion and Functional Divergence of AP2 Group Genes in Spermatophytes Determined by Molecular Evolution and Arabidopsis Mutant Analysis. Front Plant Sci, 2016. 7: p. 1383 [PMID:27703459] Sharma P, et al. Promoter Trapping and Deletion Analysis Show Arabidopsis thaliana APETALA2 Gene Promoter Is Bidirectional and Functions as a Pollen- and Ovule-Specific Promoter in the Reverse Orientation. Appl. Biochem. Biotechnol., 2017. 182(4): p. 1591-1604 [PMID:28130768] Kihira M, et al. Arabidopsis thaliana FLO2 is Involved in Efficiency of Photoassimilate Translocation, Which is Associated with Leaf Growth and Aging, Yield of Seeds and Seed Quality. Plant Cell Physiol., 2017. 58(3): p. 440-450 [PMID:28158741] Balanzà V, et al. Genetic control of meristem arrest and life span in Arabidopsis by a FRUITFULL-APETALA2 pathway. Nat Commun, 2018. 9(1): p. 565 [PMID:29422669] Dotto M,Gómez MS,Soto MS,Casati P UV-B radiation delays flowering time through changes in the PRC2 complex activity and miR156 levels in Arabidopsis thaliana. Plant Cell Environ., 2018. 41(6): p. 1394-1406 [PMID:29447428] Song C,Lee J,Kim T,Hong JC,Lim CO VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis. Planta, 2018. 247(6): p. 1439-1448 [PMID:29536220]