PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn082431

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

SBP

Protein Properties

Length: 849aa MW: 95142.3 Da PI: 6.1902

Description

SBP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn082431	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SBP	115.4	3.2e-36	126	202	1	77
--SSTT-----TT--HHHHHTT--HHHHT-S-EEETTEEEEE-TTTSSEEETTT--SS--S-STTTT-------S-- CS SBP 1 lCqvegCeadlseakeyhrrhkvCevhskapvvlvsgleqrfCqqCsrfhelsefDeekrsCrrrLakhnerrrkkq 77 +Cqv++Cead+se+k yhrrh+vC +++a++++++g+++r+CqqC++fh ls+fDe+krsCrr+L++hn+rrr+k Achn082431 126 RCQVPACEADISELKGYHRRHRVCLRCANATAIVLDGQKKRYCQQCGKFHILSDFDEGKRSCRRKLERHNNRRRRKP 202 6***********************************************************************99975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.1100.10	1.6E-27	122	188	IPR004333	Transcription factor, SBP-box
PROSITE profile	PS51141	29.393	124	201	IPR004333	Transcription factor, SBP-box
SuperFamily	SSF103612	3.01E-33	125	204	IPR004333	Transcription factor, SBP-box
Pfam	PF03110	8.0E-27	127	201	IPR004333	Transcription factor, SBP-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0055070	Biological Process	copper ion homeostasis
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 849 aa Download sequence Send to blast
MDPPTPPPPP PLSDMENPIP HYDDPLWNWS DFLDFGIDAE AQFSISLDSD ASPPEQTPPP 60 PDPENLSRIR KRDPRMTCSN FLAGRIPCAC PELDAKIAEE EDEDGSMIPG KKRVRTARAV 120 AGTMVRCQVP ACEADISELK GYHRRHRVCL RCANATAIVL DGQKKRYCQQ CGKFHILSDF 180 DEGKRSCRRK LERHNNRRRR KPSESRVAVE REPQGPVLSD DVACHNENGK DSICLSNQIT 240 EREPLLESEG QIFTLCSNPG SENIQNNSVV SFVASGEAII VGEKDESKYA RSSNCEDKSA 300 YSSVCPTGRI SFKLYDWNPA EFPRRLRHQI FQWLASMPVE LEGYIRPGCT ILTLFIAMPK 360 SMWFKLLEDP VVYIHNIVAT PAKMLSGRGT VLVYLDNVIF RAMRVGTSVM QVKVEEQAPK 420 LHYVHPRCFE AGKPAEFVAC GSNLLQPKFR FLISFAGKYL ACDHCVPSLS GDTEGVTASF 480 DHQLLKIHIP HTEPDLFGPA FIEVDNESGL SNFIPILIGN KEICSEMKIM EHSFESSLCL 540 KGSEFMTTHS SSDACEVSIQ RQTALSQFIL DTAWLLRKPA LEDIEHILPS SQIGRFNRLL 600 TFLIHNKSTC ILERVIHYME NMMDNLNLNS LANSIVDTDM KLLQSNLDNA REILCHRLQE 660 KGDSAQDSGN LVQQGGCFNR CSQIDTLSAS FFDQDMEATE RGNLDAVAGQ NSQDQCVNLP 720 LLNREVVMSM NLVGERQRKS CNRLFTKKYL VSRPLIFLIA AAAVCFGIFL IIPFDKNSVN 780 TRNSDVDLAM LVEECLDSTF SCTHLALWDS FRRHSGGGGG GYDPNWFRRH SGGGGGYDPN 840 WSWLREKI*

Sequence ? help Back to Top

Protein Sequence Length: 849 aa Download sequence Send to blast

MDPPTPPPPP PLSDMENPIP HYDDPLWNWS DFLDFGIDAE AQFSISLDSD ASPPEQTPPP  60
PDPENLSRIR KRDPRMTCSN FLAGRIPCAC PELDAKIAEE EDEDGSMIPG KKRVRTARAV  120
AGTMVRCQVP ACEADISELK GYHRRHRVCL RCANATAIVL DGQKKRYCQQ CGKFHILSDF  180
DEGKRSCRRK LERHNNRRRR KPSESRVAVE REPQGPVLSD DVACHNENGK DSICLSNQIT  240
EREPLLESEG QIFTLCSNPG SENIQNNSVV SFVASGEAII VGEKDESKYA RSSNCEDKSA  300
YSSVCPTGRI SFKLYDWNPA EFPRRLRHQI FQWLASMPVE LEGYIRPGCT ILTLFIAMPK  360
SMWFKLLEDP VVYIHNIVAT PAKMLSGRGT VLVYLDNVIF RAMRVGTSVM QVKVEEQAPK  420
LHYVHPRCFE AGKPAEFVAC GSNLLQPKFR FLISFAGKYL ACDHCVPSLS GDTEGVTASF  480
DHQLLKIHIP HTEPDLFGPA FIEVDNESGL SNFIPILIGN KEICSEMKIM EHSFESSLCL  540
KGSEFMTTHS SSDACEVSIQ RQTALSQFIL DTAWLLRKPA LEDIEHILPS SQIGRFNRLL  600
TFLIHNKSTC ILERVIHYME NMMDNLNLNS LANSIVDTDM KLLQSNLDNA REILCHRLQE  660
KGDSAQDSGN LVQQGGCFNR CSQIDTLSAS FFDQDMEATE RGNLDAVAGQ NSQDQCVNLP  720
LLNREVVMSM NLVGERQRKS CNRLFTKKYL VSRPLIFLIA AAAVCFGIFL IIPFDKNSVN  780
TRNSDVDLAM LVEECLDSTF SCTHLALWDS FRRHSGGGGG GYDPNWFRRH SGGGGGYDPN  840
WSWLREKI*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ul5_A	3e-44	122	202	1	81	squamosa promoter binding protein-like 7
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	187	199	RRKLERHNNRRRR

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that participates in reprogramming global gene expression during copper deficiency in order to improve the metal uptake and prioritize its distribution to copper proteins of major importance (Probable). Binds directly to 5'-GTAC-3' motifs in the microRNA (miRNA) promoter of the stress-responsive miRNAs miR398b and miR398c to activate their transcription. During copper deficiency, activates the copper transporters COPT1 and COPT2, and the copper chaperone CCH, directly or indirectly via miRNAs. Required for the expression of the miRNAs miR397, miR408 and miR857 (PubMed:19122104). Acts coordinately with HY5 to regulate miR408 and its target genes in response to changes in light and copper conditions (PubMed:25516599). Activates miR857 and its target genes in response to low copper conditions (PubMed:26511915). Involved in cadmium stress response by regulating miR397a, miR398b, miR398c and miR857 (PubMed:27352843). Required for iron homeostasis during copper deficiency (PubMed:22374396). {ECO:0000269\|PubMed:19122104, ECO:0000269\|PubMed:22374396, ECO:0000269\|PubMed:25516599, ECO:0000269\|PubMed:26511915, ECO:0000269\|PubMed:27352843}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00604	PBM	Transfer from AT5G18830	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028076085.1	0.0	squamosa promoter-binding-like protein 7 isoform X2
Swissprot	Q8S9G8	0.0	SPL7_ARATH; Squamosa promoter-binding-like protein 7
TrEMBL	A0A2R6PK27	0.0	A0A2R6PK27_ACTCH; Squamosa promoter-binding-like protein
STRING	VIT_05s0020g02160.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5407	24	33

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G18830.3	0.0	squamosa promoter binding protein-like 7

Publications ? help Back to Top
Zhang H, et al. MicroRNA408 is critical for the HY5-SPL7 gene network that mediates the coordinated response to light and copper. Plant Cell, 2014. 26(12): p. 4933-53 [PMID:25516599] Zhao Y, et al. MicroRNA857 Is Involved in the Regulation of Secondary Growth of Vascular Tissues in Arabidopsis. Plant Physiol., 2015. 169(4): p. 2539-52 [PMID:26511915] Perea-García A, et al. Modulation of copper deficiency responses by diurnal and circadian rhythms in Arabidopsis thaliana. J. Exp. Bot., 2016. 67(1): p. 391-403 [PMID:26516126] Gielen H,Remans T,Vangronsveld J,Cuypers A Toxicity responses of Cu and Cd: the involvement of miRNAs and the transcription factor SPL7. BMC Plant Biol., 2016. 16(1): p. 145 [PMID:27352843] Yan J, et al. Arabidopsis Pollen Fertility Requires the Transcription Factors CITF1 and SPL7 That Regulate Copper Delivery to Anthers and Jasmonic Acid Synthesis. Plant Cell, 2017. 29(12): p. 3012-3029 [PMID:29114014] Araki R, et al. SPL7 locally regulates copper-homeostasis-related genes in Arabidopsis. J. Plant Physiol., 2018. [PMID:29635212]