PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn075921

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

C2H2

Protein Properties

Length: 805aa MW: 85578.3 Da PI: 4.4047

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn075921	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14	0.00015	685	707	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + Cp C+k F++ L H+rtH Achn075921 685 FFCPECPKGFPSDRGLCGHMRTH 707 67********************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.10.20.90	1.6E-21	60	143	No hit	No description
SuperFamily	SSF54236	3.45E-22	61	149	IPR029071	Ubiquitin-related domain
SMART	SM00213	5.4E-18	62	133	IPR000626	Ubiquitin domain
PROSITE profile	PS50053	20.435	62	131	IPR000626	Ubiquitin domain
Pfam	PF00240	2.2E-19	64	131	IPR000626	Ubiquitin domain
SMART	SM00727	11	186	223	IPR006636	Heat shock chaperonin-binding
SMART	SM00727	7.1E-11	236	275	IPR006636	Heat shock chaperonin-binding
SMART	SM00727	9.8	415	461	IPR006636	Heat shock chaperonin-binding
Gene3D	G3DSA:1.10.8.10	8.4E-22	504	547	No hit	No description
PROSITE profile	PS50030	11.848	504	548	IPR015940	Ubiquitin-associated domain
SuperFamily	SSF46934	9.7E-14	505	547	IPR009060	UBA-like
SMART	SM00165	2.2E-6	509	547	IPR015940	Ubiquitin-associated domain
Pfam	PF00627	9.1E-9	509	545	IPR015940	Ubiquitin-associated domain
CDD	cd14399	1.82E-17	509	547	No hit	No description
PROSITE profile	PS50157	10.097	685	707	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.0029	685	707	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	687	707	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005515	Molecular Function	protein binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 805 aa Download sequence Send to blast
MALLSHSCHY NETRLLDSSS IDLIEETSRI ERREVLRMGG GDGGVGAAEA GDLENASCGD 60 GVTVHIRCSN GSKFSAQIGL GSTVGSFKSV IAQNCDIPAD QQRLIYKGRI LKDDQTLESY 120 GLEADHTVHL VRGFASATST NSTGVSNPGV PNSTPSGVMS VGSDEVAAIG GSDSGALLFP 180 GLGGSGGLFG AGIPEFEQVQ QQLLQNPNLM GEIMNMPLAQ NLMSNPDILW NFVLNNPQMR 240 EIIDRNPELA HVLNDPSTLR QTLEAARNPE LMREMMRNTD RAMSNIESSP EGFNMLRCMY 300 ENVQEPFLNA TTMAGDARSD LDSNPFAVLM GTRGGGQGTD QSTNPSRSGS DTTTNSPAPN 360 TNPLPNPWAS GGAGSAQTNS TTGLNTDGDA RLPATGGLGG LGLPEFGSML GSLQDTASLS 420 QLMQNPAVSQ MMQSLLSNPQ NMNQQLLALR QALRSQLGQQ LSTHGCVAVL PIAGALDNMG 480 LEMLMNMFSG LGTRISTLNR SNVPPEELYA TQLSQLQEMG FFDTRENIQA LIATAGNVHA 540 AVERLLGNTA TPVGRKITAN CRNNCQFKNF PNTINNRLAP YGYHAPNFCV VLTPFSPLSQ 600 SLQQRTMTNP GGSSDPLPDQ GGEDSNRPPP LLSGGGVGQE EKNREGEDLG AGPSRTVIEN 660 PPSPPPPPPP LAAAEVEVEE HHPLFFCPEC PKGFPSDRGL CGHMRTHKEL PWRGAFPPPM 720 FSREEFYDAG VGHLLNPPFG GENEREEGEI LANPVAGEVE EQGGEEILAA PRAEESAAGP 780 SGEEKREVPD LNEPPPCDEH GNYL*

Sequence ? help Back to Top

Protein Sequence Length: 805 aa Download sequence Send to blast

MALLSHSCHY NETRLLDSSS IDLIEETSRI ERREVLRMGG GDGGVGAAEA GDLENASCGD  60
GVTVHIRCSN GSKFSAQIGL GSTVGSFKSV IAQNCDIPAD QQRLIYKGRI LKDDQTLESY  120
GLEADHTVHL VRGFASATST NSTGVSNPGV PNSTPSGVMS VGSDEVAAIG GSDSGALLFP  180
GLGGSGGLFG AGIPEFEQVQ QQLLQNPNLM GEIMNMPLAQ NLMSNPDILW NFVLNNPQMR  240
EIIDRNPELA HVLNDPSTLR QTLEAARNPE LMREMMRNTD RAMSNIESSP EGFNMLRCMY  300
ENVQEPFLNA TTMAGDARSD LDSNPFAVLM GTRGGGQGTD QSTNPSRSGS DTTTNSPAPN  360
TNPLPNPWAS GGAGSAQTNS TTGLNTDGDA RLPATGGLGG LGLPEFGSML GSLQDTASLS  420
QLMQNPAVSQ MMQSLLSNPQ NMNQQLLALR QALRSQLGQQ LSTHGCVAVL PIAGALDNMG  480
LEMLMNMFSG LGTRISTLNR SNVPPEELYA TQLSQLQEMG FFDTRENIQA LIATAGNVHA  540
AVERLLGNTA TPVGRKITAN CRNNCQFKNF PNTINNRLAP YGYHAPNFCV VLTPFSPLSQ  600
SLQQRTMTNP GGSSDPLPDQ GGEDSNRPPP LLSGGGVGQE EKNREGEDLG AGPSRTVIEN  660
PPSPPPPPPP LAAAEVEVEE HHPLFFCPEC PKGFPSDRGL CGHMRTHKEL PWRGAFPPPM  720
FSREEFYDAG VGHLLNPPFG GENEREEGEI LANPVAGEVE EQGGEEILAA PRAEESAAGP  780
SGEEKREVPD LNEPPPCDEH GNYL*

Functional Description ? help Back to Top
Source	Description
UniProt	Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). {ECO:0000269\|PubMed:21764993}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028098141.1	0.0	ubiquitin domain-containing protein DSK2b-like isoform X4
Swissprot	Q9SII8	1e-163	DSK2B_ARATH; Ubiquitin domain-containing protein DSK2b
TrEMBL	A0A2R6S2V5	0.0	A0A2R6S2V5_ACTCH; Ubiquitin domain-containing protein
STRING	XP_002521706.1	0.0	(Ricinus communis)

Publications ? help Back to Top
Kim DY, et al. AtATM3 is involved in heavy metal resistance in Arabidopsis. Plant Physiol., 2006. 140(3): p. 922-32 [PMID:16461380] Fatimababy AS, et al. Cross-species divergence of the major recognition pathways of ubiquitylated substrates for ubiquitin/26S proteasome-mediated proteolysis. FEBS J., 2010. 277(3): p. 796-816 [PMID:20059542] Fu H,Lin YL,Fatimababy AS Proteasomal recognition of ubiquitylated substrates. Trends Plant Sci., 2010. 15(7): p. 375-86 [PMID:20399133] Lin YL, et al. The defective proteasome but not substrate recognition function is responsible for the null phenotypes of the Arabidopsis proteasome subunit RPN10. Plant Cell, 2011. 23(7): p. 2754-73 [PMID:21764993] Kaur N,Zhao Q,Xie Q,Hu J Arabidopsis RING peroxins are E3 ubiquitin ligases that interact with two homologous ubiquitin receptor proteins(F). J Integr Plant Biol, 2013. 55(1): p. 108-20 [PMID:23336935] Nolan TM, et al. Selective Autophagy of BES1 Mediated by DSK2 Balances Plant Growth and Survival. Dev. Cell, 2017. 41(1): p. 33-46.e7 [PMID:28399398]