PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn049361

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

C2H2

Protein Properties

Length: 333aa MW: 38717.1 Da PI: 6.5831

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn049361	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.3	0.00012	195	217	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y C+ C + +rk++L+rH+r++ Achn049361 195 YFCEFCLTFMKRKEQLQRHMRKC 217 78*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54160	2.29E-26	46	162	IPR016197	Chromo domain-like
Gene3D	G3DSA:2.30.30.270	5.8E-38	48	122	No hit	No description
Pfam	PF11717	2.2E-21	54	110	IPR025995	RNA binding activity-knot of a chromodomain
CDD	cd00024	7.23E-8	67	111	No hit	No description
SMART	SM00298	1.5E-5	68	125	IPR000953	Chromo/chromo shadow domain
Gene3D	G3DSA:2.30.30.270	5.8E-38	156	206	No hit	No description
PROSITE profile	PS51726	40.899	161	332	IPR002717	Histone acetyltransferase domain, MYST-type
SuperFamily	SSF55729	7.95E-53	162	294	IPR016181	Acyl-CoA N-acyltransferase
Gene3D	G3DSA:3.40.630.30	1.9E-34	220	294	IPR016181	Acyl-CoA N-acyltransferase
Pfam	PF01853	2.9E-33	222	293	IPR002717	Histone acetyltransferase domain, MYST-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0016747	Molecular Function	transferase activity, transferring acyl groups other than amino-acyl groups

Sequence ? help Back to Top
Protein Sequence Length: 333 aa Download sequence Send to blast
MGSIDAPTSK EKGSTLSSGV AQNQPAGDVP SPPPADSGTE NDTSRKRKSS ALPLEVGTRV 60 MCRWRDGKFH QVKVIERRRT QNGDDYEYYV HYTEFNRRLD EWVKLEQLDL DSVETVIDEK 120 VEEKVTSLKM TRHQKRKIDE THVEGHEELD AASLREHEEF TKVKNIATIE LGRYEIETWY 180 FSPFPPEYND SLKMYFCEFC LTFMKRKEQL QRHMRKCDLK HPPGDEIYRS GTLSMFEVDG 240 KKNKVYGQNL CYLAKLFLDH KTLYYDVDLF LFYVLCECDD RGCHMVGYFS KSYRGEPQIS 300 ALIPEFGSKL PRICGIIFIV QIHFMGERIV QL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5gk9_A	1e-58	166	291	2	127	Histone acetyltransferase KAT7
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	43	48	SRKRKS

Functional Description ? help Back to Top
Source	Description
UniProt	Histone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269\|PubMed:17877703, ECO:0000269\|PubMed:19040736, ECO:0000269\|PubMed:22170978, ECO:0000269\|PubMed:23273925}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269\|PubMed:22170978}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028106659.1	0.0	histone acetyltransferase of the MYST family 1-like
Swissprot	Q9FLF7	1e-173	MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBL	A0A0D2UT38	0.0	A0A0D2UT38_GOSRA; Histone acetyltransferase
STRING	Gorai.009G242400.1	1e-180	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4391	3	3

Publications ? help Back to Top
Latrasse D, et al. The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis. BMC Plant Biol., 2008. 8: p. 121 [PMID:19040736] Campi M,D'Andrea L,Emiliani J,Casati P Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA. Plant Physiol., 2012. 158(2): p. 981-95 [PMID:22170978] Bari A,Orazova S,Ivashchenko A miR156- and miR171-binding sites in the protein-coding sequences of several plant genes. Biomed Res Int, 2013. 2013: p. 307145 [PMID:23936788] Xu Y, et al. Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes. Nucleic Acids Res., 2014. 42(17): p. 10960-74 [PMID:25183522] Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB 3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana. J Mol Model, 2016. 22(11): p. 256 [PMID:27709438] Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis. Front Plant Sci, 2017. 8: p. 1179 [PMID:28740501]