PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan021764

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

ARF

Protein Properties

Length: 515aa MW: 57623.5 Da PI: 8.5864

Description

ARF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S41958796	PU_unref	Unigene	View CDS
gnl\|UG\|Aan#S41974092	PU_unref	Unigene	View CDS
PUT-183a-Artemisia_annua-832160992	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	75.5	6e-24	72	173	1	99
EEEE-..-HHHHTT-EE--HHH.HTT.....---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEE CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh.....ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvk 95 f+k+lt sd++++g +++p++ ae++ ++++ s++l+ +d++g +W++++iyr++++r++lt+GW+ Fv+ ++L gD v+F + +++ l+++ Aan021764 72 FCKTLTASDTSTHGGFSVPRRAAEDCfppldYKQPRPSQELVAKDLHGTEWKFRHIYRGQPRRHLLTTGWSAFVNKKKLVCGDAVLFL--RGDDGVLRLG 169 99**************************945566778***********************************************..3478889999 PP EE-S CS B3 96 vfrk 99 ++r+ Aan021764 170 IRRA 173 9997 PP
2	Auxin_resp	109.9	2.7e-36	198	279	1	82
Auxin_resp 1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsL 82 +++++s++s+F+v+YnPr ++seF+v++++++k+l++++s+GmRfkm++e+ed rr +G+++g++d+d++rWp+SkWr+L Aan021764 198 VVNSISQRSPFSVCYNPRGGSSEFIVPYNRFLKSLSCSFSPGMRFKMRVESEDGGDRRSTGIITGLNDTDSSRWPGSKWRCL 279 6899*****************************************************************************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.40.330.10	5.0E-40	64	175	IPR015300	DNA-binding pseudobarrel domain
SuperFamily	SSF101936	3.01E-41	66	173	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	3.54E-23	70	172	No hit	No description
SMART	SM01019	4.8E-23	72	174	IPR003340	B3 DNA binding domain
Pfam	PF02362	3.3E-22	72	173	IPR003340	B3 DNA binding domain
PROSITE profile	PS50863	13.183	72	174	IPR003340	B3 DNA binding domain
Pfam	PF06507	6.5E-31	199	279	IPR010525	Auxin response factor

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009725	Biological Process	response to hormone
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 515 aa Download sequence Send to blast
XTSGEFSIAP HVFCRVVDVK LHAEAGNDDV YAQVSLIQDP QLEQKWREGV RGAEYADDDN 60 GVAEKSTTPH MFCKTLTASD TSTHGGFSVP RRAAEDCFPP LDYKQPRPSQ ELVAKDLHGT 120 EWKFRHIYRG QPRRHLLTTG WSAFVNKKKL VCGDAVLFLR GDDGVLRLGI RRASQVKVAS 180 NLPSFCSQQL NNFDFSSVVN SISQRSPFSV CYNPRGGSSE FIVPYNRFLK SLSCSFSPGM 240 RFKMRVESED GGDRRSTGII TGLNDTDSSR WPGSKWRCLM VRWDCMEVTK QTRVSPWEIE 300 RCGSVSEVES FVTPLTKRSR TGFPPILNDR ISGASDFGES MRFHKVLQGQ EIYGFHRSPN 360 INGLNNDIRN QTSVGFGESL GFNRVLQGQE IMSNIQYGER LSNIGSLFSS PSSVLRFQQT 420 MSQAANAYPI RYADNMKPLS DQNHQGFFTP VRMQQEEPVL KSANSCRLFG FSLTEGTNVT 480 QCPTGPAVNT KVGGSCTNER VHQWYRSSDG FLQGL

Sequence ? help Back to Top

Protein Sequence Length: 515 aa Download sequence Send to blast

XTSGEFSIAP HVFCRVVDVK LHAEAGNDDV YAQVSLIQDP QLEQKWREGV RGAEYADDDN  60
GVAEKSTTPH MFCKTLTASD TSTHGGFSVP RRAAEDCFPP LDYKQPRPSQ ELVAKDLHGT  120
EWKFRHIYRG QPRRHLLTTG WSAFVNKKKL VCGDAVLFLR GDDGVLRLGI RRASQVKVAS  180
NLPSFCSQQL NNFDFSSVVN SISQRSPFSV CYNPRGGSSE FIVPYNRFLK SLSCSFSPGM  240
RFKMRVESED GGDRRSTGII TGLNDTDSSR WPGSKWRCLM VRWDCMEVTK QTRVSPWEIE  300
RCGSVSEVES FVTPLTKRSR TGFPPILNDR ISGASDFGES MRFHKVLQGQ EIYGFHRSPN  360
INGLNNDIRN QTSVGFGESL GFNRVLQGQE IMSNIQYGER LSNIGSLFSS PSSVLRFQQT  420
MSQAANAYPI RYADNMKPLS DQNHQGFFTP VRMQQEEPVL KSANSCRLFG FSLTEGTNVT  480
QCPTGPAVNT KVGGSCTNER VHQWYRSSDG FLQGL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldy_A	2e-90	6	307	67	360	Auxin response factor 1
4ldy_B	2e-90	6	307	67	360	Auxin response factor 1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Detected during gynoecium development.
Uniprot	TISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269\|PubMed:10476078, ECO:0000269\|PubMed:9409666}.

Functional Description ? help Back to Top
Source	Description
UniProt	Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Involved in the establishment or elaboration of tissue patterning during gynoecial development. {ECO:0000269\|PubMed:10952886, ECO:0000269\|PubMed:12036261}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by AHL21/GIK. {ECO:0000269\|PubMed:19956801}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024993273.1	0.0	auxin response factor 3-like isoform X4
Swissprot	O23661	1e-159	ARFC_ARATH; Auxin response factor 3
TrEMBL	A0A2U1QDI7	0.0	A0A2U1QDI7_ARTAN; Auxin response factor
STRING	XP_002522498.1	1e-175	(Ricinus communis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G33860.1	1e-162	ARF family protein

Publications ? help Back to Top
Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors. Mol. Gen. Mikrobiol. Virusol., 2013. [PMID:24003511] Thoma R,Chandler JW Polarity in the early floral meristem of Arabidopsis. Plant Signal Behav, 2015. 10(4): p. e992733 [PMID:25806573] Lora J,Hormaza JI,Herrero M Transition from two to one integument in Prunus species: expression pattern of INNER NO OUTER (INO), ABERRANT TESTA SHAPE (ATS) and ETTIN (ETT). New Phytol., 2015. 208(2): p. 584-95 [PMID:25991552] Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis. Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71 [PMID:26108442] Cabrera J, et al. Differentially expressed small RNAs in Arabidopsis galls formed by Meloidogyne javanica: a functional role for miR390 and its TAS3-derived tasiRNAs. New Phytol., 2016. 209(4): p. 1625-40 [PMID:26542733] Husbands AY,Benkovics AH,Nogueira FT,Lodha M,Timmermans MC The ASYMMETRIC LEAVES Complex Employs Multiple Modes of Regulation to Affect Adaxial-Abaxial Patterning and Leaf Complexity. Plant Cell, 2015. 27(12): p. 3321-35 [PMID:26589551] Yamaguchi N,Wu MF,Winter CM,Wagner D LEAFY and Polar Auxin Transport Coordinately Regulate Arabidopsis Flower Development. Plants (Basel), 2014. 3(2): p. 251-65 [PMID:27135503] Matsumura Y, et al. A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis. Biol Open, 2016. 5(7): p. 942-54 [PMID:27334696] Simonini S, et al. A noncanonical auxin-sensing mechanism is required for organ morphogenesis in Arabidopsis. Genes Dev., 2016. 30(20): p. 2286-2296 [PMID:27898393] Pfannebecker KC,Lange M,Rupp O,Becker A An Evolutionary Framework for Carpel Developmental Control Genes. Mol. Biol. Evol., 2017. 34(2): p. 330-348 [PMID:28049761] Wójcikowska B,Gaj MD Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis. Plant Cell Rep., 2017. 36(6): p. 843-858 [PMID:28255787] Su Z, et al. The THO Complex Non-Cell-Autonomously Represses Female Germline Specification through the TAS3-ARF3 Module. Curr. Biol., 2017. 27(11): p. 1597-1609.e2 [PMID:28552357] Simonini S,Bencivenga S,Trick M,Østergaard L Auxin-Induced Modulation of ETTIN Activity Orchestrates Gene Expression in Arabidopsis. Plant Cell, 2017. 29(8): p. 1864-1882 [PMID:28804059] Guan C, et al. Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis. Curr. Biol., 2017. 27(19): p. 2940-2950.e4 [PMID:28943086] Simonini S, et al. Corrigendum: A noncanonical auxin-sensing mechanism is required for organ morphogenesis in Arabidopsis. Genes Dev., 2017. 31(17): p. 1821 [PMID:28982764] Zhang K, et al. AUXIN RESPONSE FACTOR3 Regulates Floral Meristem Determinacy by Repressing Cytokinin Biosynthesis and Signaling. Plant Cell, 2018. 30(2): p. 324-346 [PMID:29371438] Vial-Pradel S, et al. Arabidopsis Zinc-Finger-Like Protein ASYMMETRIC LEAVES2 (AS2) and Two Nucleolar Proteins Maintain Gene Body DNA Methylation in the Leaf Polarity Gene ETTIN (ARF3). Plant Cell Physiol., 2018. 59(7): p. 1385-1397 [PMID:29415182] Simonini S,Stephenson P,Østergaard L A molecular framework controlling style morphology in Brassicaceae. Development, 2018. [PMID:29440299] Andres-Robin A, et al. Evidence for the Regulation of Gynoecium Morphogenesis by ETTIN via Cell Wall Dynamics. Plant Physiol., 2018. 178(3): p. 1222-1232 [PMID:30237208] Hablak SG Features inheritance of root system Arabidopsis thaliana (L.) Heynh. the interaction of genes CTR1 AND ALF3, NPH4 and IAR2. Tsitol. Genet., 2019. [PMID:30484609]