 |
Plant Transcription
Factor Database
|
Transcription Factor Information
|
Basic
Information? help
Back to Top |
| TF ID |
AT5G66350.1 |
| Common Name | SHI |
| Organism |
|
| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
|
| Family |
SRS |
| Protein Properties |
Length: 331aa MW: 35376.8 Da PI: 8.2647 |
| Description |
Lateral root primordium (LRP) protein-related |
| Gene Model |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | DUF702 | 227.4 | 2.7e-70 | 115 | 263 | 3 | 154 |
DUF702 3 sgtasCqdCGnqakkdCaheRCRtCCksrgfdCathvkstWvpaakrrerqqqlaaasskaaasaaeaaskrkrelkskkqsalsstklssaeskkel 100
sg+ sCqdCGnq+kkdC+h+RCRtCCksrg+dC thvkstWvpaakrrerqqql++ ++ ++ + +kr+re +++++++ t+++s++++ l
AT5G66350.1 115 SGGPSCQDCGNQSKKDCSHMRCRTCCKSRGLDCPTHVKSTWVPAAKRRERQQQLSTGQQ--PQQLGGSVPKRQRERIPARSTSMAYTRIPSNNTS-GL 209
68889***********************************************9998755..55779999*********************99866.99 PP
DUF702 101 etsslPeevsseavfrcvrvssvddgeeelaYqtavsigGhvfkGiLydqGlee 154
e+ ++P+evss+avfrcvrvssvdd+eee+aY+tavsigGhvfkG+LydqG++e
AT5G66350.1 210 EVGNFPPEVSSSAVFRCVRVSSVDDEEEEYAYKTAVSIGGHVFKGVLYDQGPAE 263
999************************************************986 PP
|
| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0007275 | Biological Process | multicellular organism development |
| GO:0009734 | Biological Process | auxin-activated signaling pathway |
| GO:0009851 | Biological Process | auxin biosynthetic process |
| GO:0009938 | Biological Process | negative regulation of gibberellic acid mediated signaling pathway |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| GO:0046872 | Molecular Function | metal ion binding |
| GO:0046982 | Molecular Function | protein heterodimerization activity |
| Sequence ? help Back to Top |
| Protein Sequence Length: 331 aa
Download sequence Send
to blast |
MAGFFSLGHG GGGNTPDNHR TNTNNPSSSG TESWLWCRNP NSNADGGEAG PSYKGTLELW 60
QHPNNQEIIF QQQQQQQQRL DLYTSAAGLG VGPSNRSLIE TSGGALMMMR SGSGSGGPSC 120
QDCGNQSKKD CSHMRCRTCC KSRGLDCPTH VKSTWVPAAK RRERQQQLST GQQPQQLGGS 180
VPKRQRERIP ARSTSMAYTR IPSNNTSGLE VGNFPPEVSS SAVFRCVRVS SVDDEEEEYA 240
YKTAVSIGGH VFKGVLYDQG PAERSSSGGG SQPLNLITAG PSASSSSPNV SCNNGVVGST 300
SDHYIDPASL NYPTPINTFM TGTHFFSNSR S
|
| Expression --
Description ? help
Back to Top |
| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: In germinating seeds, first detected at about 48 h after imbibition. In young seedlings grown in continuous light, present in the root/shoot transition zone, in the apex, and in the apical region of the cotyledons. Later observed in lateral root primordia and in emerging lateral roots, particularly in the root tips, as well as in the shoot apex and in the new leaves, especially in the apical and lateral hydathodes. In adult plants, accumulates in lateral root tips, lateral root primordia, and axillary shoot primordia. In flowers, expressed in the style and stigmatic surface of the pistil and in the receptacle (base) of the flower throughout the development of the pistil until anthesis and later in the silique. Fades out after fertilization. {ECO:0000269|PubMed:11706176, ECO:0000269|PubMed:16740146}. |
| Uniprot | TISSUE SPECIFICITY: Expressed in young organs such as shoot apices and root tips. Present in roots, stems, flowers, leaves, hydathodes and siliques. {ECO:0000269|PubMed:10368174, ECO:0000269|PubMed:11706176}. |
| Functional Description ? help
Back to Top |
| Source |
Description |
| TAIR | A member of SHI gene family. Arabidopsis thaliana has ten members that encode proteins with a RING finger-like zinc finger motif. Despite being highly divergent in sequence, many of the SHI-related genes are partially redundant in function and synergistically promote gynoecium, stamen and leaf development in Arabidopsis. Shi mutant is dominant, has dwarf phenotype. Loss of function mutations have no observable phenotype. Putative zinc finger protein. Involved in the response to gibberellic acid. |
| UniProt | Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering. Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning. Promotes style and stigma formation, and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM). Suppressor of the gibberellin (GA) signal transduction. {ECO:0000269|PubMed:10368174, ECO:0000269|PubMed:11706176, ECO:0000269|PubMed:16740146}. |
| Function -- GeneRIF ? help
Back to Top |
- At least six SHI-related genes contribute to carpel fusion as well as to the formation of all marginal tissues in the apical part of the gynoecium.
[PMID: 16740146]
|
| Phenotype -- Disruption Phenotype ? help
Back to Top |
| Source |
Description |
| UniProt | DISRUPTION PHENOTYPE: High gibberellin (GA) levels associated with dwarfism, short hypocotyl, narrow leaves, reduced apical dominance, and late flowering, but more flowers. {ECO:0000269|PubMed:10368174, ECO:0000269|PubMed:11706176, ECO:0000269|PubMed:16740146}. |
| Annotation --
Nucleotide ? help
Back to Top |
| Source |
Hit ID |
E-value |
Description |
| GenBank | AF152555 | 0.0 | AF152555.1 Arabidopsis thaliana putative zinc finger protein SHI (SHI) mRNA, complete cds. |
| Publications
? help Back to Top |
- Fridborg I,Kuusk S,Moritz T,Sundberg E
The Arabidopsis dwarf mutant shi exhibits reduced gibberellin responses conferred by overexpression of a new putative zinc finger protein.
Plant Cell, 1999. 11(6): p. 1019-32
[PMID:10368174] - Fridborg I,Kuusk S,Robertson M,Sundberg E
The Arabidopsis protein SHI represses gibberellin responses in Arabidopsis and barley.
Plant Physiol., 2001. 127(3): p. 937-48
[PMID:11706176] - Smith HM,Hake S
The interaction of two homeobox genes, BREVIPEDICELLUS and PENNYWISE, regulates internode patterning in the Arabidopsis inflorescence.
Plant Cell, 2003. 15(8): p. 1717-27
[PMID:12897247] - Kuusk S,Sohlberg JJ,Magnus Eklund D,Sundberg E
Functionally redundant SHI family genes regulate Arabidopsis gynoecium development in a dose-dependent manner.
Plant J., 2006. 47(1): p. 99-111
[PMID:16740146] - L
Production of compact plants by overexpression of AtSHI in the ornamental Kalancho
Plant Biotechnol. J., 2010. 8(2): p. 211-22
[PMID:20051037] - Eklund DM, et al.
Homologues of the Arabidopsis thaliana SHI/STY/LRP1 genes control auxin biosynthesis and affect growth and development in the moss Physcomitrella patens.
Development, 2010. 137(8): p. 1275-84
[PMID:20223761] - Zawaski C, et al.
SHORT INTERNODES-like genes regulate shoot growth and xylem proliferation in Populus.
New Phytol., 2011. 191(3): p. 678-91
[PMID:21564099] - Eklund DM, et al.
Expression of Arabidopsis SHORT INTERNODES/STYLISH family genes in auxin biosynthesis zones of aerial organs is dependent on a GCC box-like regulatory element.
Plant Physiol., 2011. 157(4): p. 2069-80
[PMID:21976484] - Meinke DW
A survey of dominant mutations in Arabidopsis thaliana.
Trends Plant Sci., 2013. 18(2): p. 84-91
[PMID:22995285] - Baylis T,Cierlik I,Sundberg E,Mattsson J
SHORT INTERNODES/STYLISH genes, regulators of auxin biosynthesis, are involved in leaf vein development in Arabidopsis thaliana.
New Phytol., 2013. 197(3): p. 737-50
[PMID:23293954] - Islam MA, et al.
Overexpression of the AtSHI gene in poinsettia, Euphorbia pulcherrima, results in compact plants.
PLoS ONE, 2013. 8(1): p. e53377
[PMID:23308204] - Pfannebecker KC,Lange M,Rupp O,Becker A
An Evolutionary Framework for Carpel Developmental Control Genes.
Mol. Biol. Evol., 2017. 34(2): p. 330-348
[PMID:28049761] - Estornell LH,Landberg K,Cierlik I,Sundberg E
SHI/STY Genes Affect Pre- and Post-meiotic Anther Processes in Auxin Sensing Domains in Arabidopsis.
Front Plant Sci, 2018. 9: p. 150
[PMID:29491878]
|
