PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 281aa MW: 30569.8 Da PI: 6.0652

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT5G62610.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	34.5	3.8e-11	164	210	5	55
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 h+ +Er RR++i +++ L++++P + +k Ka +L + ++YI+sLq AT5G62610.1 164 HSLAERARREKISEKMTALQDIIPGC----NKIIGKALVLDEIINYIQSLQ 210 999*********************....999***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	6.83E-10	157	214	No hit	No description
SuperFamily	SSF47459	6.41E-17	157	224	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.18	159	209	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.5E-17	160	224	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.4E-8	164	210	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	9.9E-10	165	215	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 281 aa Download sequence Send to blast
MDPPLVNDSS FSAANPSSYT LSEIWPFPVN DAVRSGLRLA VNSGRVFTRS EHSGNKDVSA 60 AEESTVTDLT AGWGSRKTRD LNSEDDSSKM VSSSSSGNEL KESGDKKRKL CGSESGNGDG 120 SMRPEGETSS GGGGSKATEQ KNKPEPPKDY IHVRARRGQA TDRHSLAERA RREKISEKMT 180 ALQDIIPGCN KIIGKALVLD EIINYIQSLQ RQVEFLSMKL EVVNSGASTG PTIGVFPSGD 240 LGTLPIDVHR TIYEQQEANE TRVSQPEWLH MQVDGNFNRT T

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	99	108	LKESGDKKRK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.24534	0.0	flower\| seed

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	247430_at	0.0
Expression Atlas	AT5G62610	-
AtGenExpress	AT5G62610	-
ATTED-II	AT5G62610	-

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT5G62610.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT5G62610

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY072104	0.0	AY072104.1 Arabidopsis thaliana unknown protein (At5g62610) mRNA, complete cds.
GenBank	AY084578	0.0	AY084578.1 Arabidopsis thaliana clone 112281 mRNA, complete sequence.
GenBank	AY123023	0.0	AY123023.1 Arabidopsis thaliana unknown protein (At5g62610) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001330306.1	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Refseq	NP_201067.1	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	Q9LV17	0.0	BH079_ARATH; Transcription factor bHLH79
TrEMBL	A0A178UAT6	0.0	A0A178UAT6_ARATH; Uncharacterized protein
STRING	AT5G62610.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1855	28	78
Representative plant	OGRP58	16	313

Link Out ? help Back to Top
Phytozome	AT5G62610.1
Entrez Gene	836382
iHOP	AT5G62610
wikigenes	AT5G62610

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Mandaokar A,Kumar VD,Amway M,Browse J Microarray and differential display identify genes involved in jasmonate-dependent anther development. Plant Mol. Biol., 2003. 52(4): p. 775-86 [PMID:13677466] Dal Bosco C, et al. Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. J. Biol. Chem., 2004. 279(2): p. 1060-9 [PMID:14576160] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Bailey PC, et al. Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] Wang XJ,Cao XL,Hong Y Isolation and characterization of flower-specific transcripts in Acacia mangium. Tree Physiol., 2005. 25(2): p. 167-78 [PMID:15574398] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474]