PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G57150.3
Common NameBHLH35, EN41, MUL3.10
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 219aa    MW: 24777.1 Da    PI: 4.6219
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G57150.3genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH421.7e-1358101755
                  HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                    Er+RR+++N++++ Lr+++P+      +K++Ka+i + A+ YI  Lq
  AT5G57150.3  58 VSERNRRQKLNQRLFALRSVVPNI-----TKMDKASIIKDAISYIEGLQ 101
                  57*********************7.....7****************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.79651100IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.71E-1254101No hitNo description
SuperFamilySSF474593.79E-1754117IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.106.0E-1757116IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003537.2E-1457106IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000105.0E-1158101IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0016021Cellular Componentintegral component of membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 219 aa     Download sequence    Send to blast
MEDIVDQELS NYWEPSSFLQ NEDFEYDRSW PLEEAISGSY DSSSPDGAAS SPASKNIVSE  60
RNRRQKLNQR LFALRSVVPN ITKMDKASII KDAISYIEGL QYEEKKLEAE IRELESTPKS  120
SLSFSKDFDR DLLVPVTSKK MKQLDSGSST SLIEVLELKV TFMGERTMVV SVTCNKRTDT  180
MVKLCEVFES LNLKILTSNL TSFSGMIFHT VFIEIAIAN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A5e-1456110963Transcription factor MYC2
5gnj_B5e-1456110963Transcription factor MYC2
5gnj_E5e-1456110963Transcription factor MYC2
5gnj_F5e-1456110963Transcription factor MYC2
5gnj_G5e-1456110963Transcription factor MYC2
5gnj_I5e-1456110963Transcription factor MYC2
5gnj_M5e-1456110963Transcription factor MYC2
5gnj_N5e-1456110963Transcription factor MYC2
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.491810.0seed
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible247945_at0.0
Expression AtlasAT5G57150-
AtGenExpressAT5G57150-
ATTED-IIAT5G57150-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Function -- GeneRIF ? help Back to Top
  1. survey of the MYB proteins that interact with R/B-like Bbasic helix-loop-helix proteins
    [PMID: 15361138]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G57150.3
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G57150
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0580720.0AY058072.1 Arabidopsis thaliana AT5g57150/MUL3_10 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_974947.11e-159basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ2HIV91e-156BH035_ARATH; Transcription factor bHLH35
TrEMBLA0A178UEA81e-155A0A178UEA8_ARATH; Uncharacterized protein
STRINGAT5G57150.41e-153(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  7. Zimmermann IM,Heim MA,Weisshaar B,Uhrig JF
    Comprehensive identification of Arabidopsis thaliana MYB transcription factors interacting with R/B-like BHLH proteins.
    Plant J., 2004. 40(1): p. 22-34
    [PMID:15361138]
  8. Bauer P, et al.
    Analysis of sequence, map position, and gene expression reveals conserved essential genes for iron uptake in Arabidopsis and tomato.
    Plant Physiol., 2004. 136(4): p. 4169-83
    [PMID:15531708]
  9. Thimmapuram J,Duan H,Liu L,Schuler MA
    Bicistronic and fused monocistronic transcripts are derived from adjacent loci in the Arabidopsis genome.
    RNA, 2005. 11(2): p. 128-38
    [PMID:15659355]
  10. Truman W,de Zabala MT,Grant M
    Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance.
    Plant J., 2006. 46(1): p. 14-33
    [PMID:16553893]
  11. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  12. Gong W, et al.
    The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors.
    Mol Plant, 2008. 1(1): p. 27-41
    [PMID:19802365]