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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT5G39660.1 |
| Common Name | CDF2, DOF5.2, MIJ24.16 |
| Organism |
|
| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
Dof |
| Protein Properties |
Length: 457aa MW: 49808.1 Da PI: 4.9386 |
| Description |
cycling DOF factor 2 |
| Gene Model |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | zf-Dof | 124.6 | 3.1e-39 | 134 | 193 | 2 | 61 |
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkks 61
++k+l+cprC+s++tkfCyynny+++qPr+fCk+C+ryWt+GG++rnvPvG+grrknk+
AT5G39660.1 134 PDKILPCPRCNSMETKFCYYNNYNVNQPRHFCKKCQRYWTAGGTMRNVPVGAGRRKNKSP 193
7899*****************************************************986 PP
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| Sequence ? help Back to Top |
| Protein Sequence Length: 457 aa
Download sequence Send
to blast |
MADPAIKLFG KTIPLPELGV VDSSSSYTGF LTETQIPVRL SDSCTGDDDD EEMGDSGLGR 60
EEGDDVGDGG GESETDKKEE KDSECQEESL RNESNDVTTT TSGITEKTET TKAAKTNEES 120
GGTACSQEGK LKKPDKILPC PRCNSMETKF CYYNNYNVNQ PRHFCKKCQR YWTAGGTMRN 180
VPVGAGRRKN KSPASHYNRH VSITSAEAMQ KVARTDLQHP NGANLLTFGS DSVLCESMAS 240
GLNLVEKSLL KTQTVLQEPN EGLKITVPLN QTNEEAGTVS PLPKVPCFPG PPPTWPYAWN 300
GVSWTILPFY PPPAYWSCPG VSPGAWNSFT WMPQPNSPSG SNPNSPTLGK HSRDENAAEP 360
GTAFDETESL GREKSKPERC LWVPKTLRID DPEEAAKSSI WETLGIKKDE NADTFGAFRS 420
STKEKSSLSE GRLPGRRPEL QANPAALSRS ANFHESS
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | TISSUE SPECIFICITY: Expressed in the vasculature of cotyledons and hypocotyls, leaves and roots. {ECO:0000269|PubMed:19619493}. |
| Functional Description ? help
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| Source |
Description |
| TAIR | Dof-type zinc finger domain-containing protein, identical to H-protein promoter binding factor-2a GI:3386546 from (Arabidopsis thaliana). Interacts with LKP2 and FKF1, but its overexpression does not change flowering time under short or long day conditions. |
| UniProt | Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The stability of CDF2 is controlled by 'GIGANTEA' and redundantly by ADO3, ADO2 and/or ADO1. {ECO:0000250, ECO:0000269|PubMed:19619493}. |
| Function -- GeneRIF ? help
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- Data suggest that antagonism between GIGANTEA and DOF transcription factors contributes to photoperiodic flowering by modulating an underlying diurnal rhythm in CONSTANS transcript levels [CDF2].
[PMID: 19619493] - Detailed expression studies followed by phenotypic assays showed that the CDFs function downstream of GI, influencing responses to freezing temperatures and growth, but are not necessary for proper clock function.
[PMID: 25600594] - We conclude that CDF2 regulates a group of pri-miRNAs at both the transcriptional and posttranscriptional levels to maintain proper levels of their mature miRNAs to control plant development.
[PMID: 26473486]
|
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Circadian-regulation. Highly expressed at the beginning of the light period, then decreases, reaching a minimum between 16 and 29 hours after dawn before rising again at the end of the day. Regulated at the protein level by ADO3 and GI pos-transcriptionally. {ECO:0000269|PubMed:19619493}. |
| Phenotype -- Disruption Phenotype ? help
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| Source |
Description |
| UniProt | DISRUPTION PHENOTYPE: Early flowering. {ECO:0000269|PubMed:19619493}. |
| Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Yanagisawa S
The Dof family of plant transcription factors.
Trends Plant Sci., 2002. 7(12): p. 555-60
[PMID:12475498] - Lijavetzky D,Carbonero P,Vicente-Carbajosa J
Genome-wide comparative phylogenetic analysis of the rice and Arabidopsis Dof gene families.
BMC Evol. Biol., 2003. 3: p. 17
[PMID:12877745] - Yamada K, et al.
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Science, 2003. 302(5646): p. 842-6
[PMID:14593172] - Rohde A, et al.
Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism.
Plant Cell, 2004. 16(10): p. 2749-71
[PMID:15377757] - Imaizumi T,Schultz TF,Harmon FG,Ho LA,Kay SA
FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis.
Science, 2005. 309(5732): p. 293-7
[PMID:16002617] - Chawade A,Br
Putative cold acclimation pathways in Arabidopsis thaliana identified by a combined analysis of mRNA co-expression patterns, promoter motifs and transcription factors.
BMC Genomics, 2007. 8: p. 304
[PMID:17764576] - Usadel B, et al.
Global transcript levels respond to small changes of the carbon status during progressive exhaustion of carbohydrates in Arabidopsis rosettes.
Plant Physiol., 2008. 146(4): p. 1834-61
[PMID:18305208] - Borges F, et al.
Comparative transcriptomics of Arabidopsis sperm cells.
Plant Physiol., 2008. 148(2): p. 1168-81
[PMID:18667720] - Wang Y, et al.
Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
Plant Physiol., 2008. 148(3): p. 1201-11
[PMID:18775970] - Budhiraja R, et al.
Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation.
Plant Physiol., 2009. 149(3): p. 1529-40
[PMID:19151129] - Fornara F, et al.
Arabidopsis DOF transcription factors act redundantly to reduce CONSTANS expression and are essential for a photoperiodic flowering response.
Dev. Cell, 2009. 17(1): p. 75-86
[PMID:19619493] - Arabidopsis Interactome Mapping Consortium
Evidence for network evolution in an Arabidopsis interactome map.
Science, 2011. 333(6042): p. 601-7
[PMID:21798944] - Elrouby N,Bonequi MV,Porri A,Coupland G
Identification of Arabidopsis SUMO-interacting proteins that regulate chromatin activity and developmental transitions.
Proc. Natl. Acad. Sci. U.S.A., 2013. 110(49): p. 19956-61
[PMID:24255109] - Ding Y, et al.
Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
BMC Plant Biol., 2013. 13: p. 229
[PMID:24377444] - Fornara F, et al.
The GI-CDF module of Arabidopsis affects freezing tolerance and growth as well as flowering.
Plant J., 2015. 81(5): p. 695-706
[PMID:25600594] - Sun Z,Guo T,Liu Y,Liu Q,Fang Y
The Roles of Arabidopsis CDF2 in Transcriptional and Posttranscriptional Regulation of Primary MicroRNAs.
PLoS Genet., 2015. 11(10): p. e1005598
[PMID:26473486]
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