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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT5G35770.1 |
| Common Name | MXH1.20, SAP |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
SAP |
| Protein Properties |
Length: 446aa MW: 49306.5 Da PI: 6.7443 |
| Description |
SAP family protein |
| Gene Model |
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| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | SAP | 752.5 | 3.3e-229 | 2 | 445 | 2 | 454 |
SAP 2 ssssssssseseegseggeggdassgesegpsssrqr.aanevwpePflealatqvaidasrslGrlaaasalanvfqvcstwravsrsdllwqrltr 98
s+sss ++++g + s+g +e+ps sr+r an+vwpePfle+la+qva++as+s+G laaa+alanvf+vc+tw+avsrsd+lwq l+r
AT5G35770.1 2 STSSS----------SSDNGAGGSGGVFEAPSPSRPRrGANDVWPEPFLESLAVQVAVNASTSAGLLAAAPALANVFRVCTTWHAVSRSDHLWQLLSR 89
33333..........3344455566899******998799********************************************************** PP
SAP 99 riWrrtkllrdtWreeyiyrhrtarnfrtrrysyvtlqfdpadvdedndadalsCrclalsdkylaaGfadGavrlfdletrlhvstflpqhrdrlGr 196
++W+rt+l++dtWr+e+iyrhrtarnfrtr+++y+tlqfdp+dvde +d+lsCrcl+lsd ylaaGfadG+vrlf l++rlhv+t++p rdr+Gr
AT5G35770.1 90 QVWARTHLMHDTWRDEFIYRHRTARNFRTRTHTYFTLQFDPSDVDE---PDSLSCRCLTLSDLYLAAGFADGTVRLFLLNNRLHVRTLRPPLRDRFGR 184
******************************************9998...689********************************************** PP
SAP 197 fsravsGivisdsrlvfatldGdihvavidgagaaaarrallGdvvndGalvdfaGsgrWwvGlyaGvpGrafhiWdaeteelvfvGGsltdPeavmG 294
fsravsGivisdsrl+fat+dGdihva+idg ++++r+a++Gd+vndGalvdf+G+grWwvGl+aGvpGrafhiWd+++ee++fvGG+ltdPeavmG
AT5G35770.1 185 FSRAVSGIVISDSRLTFATMDGDIHVAEIDG--VGHTRTAYAGDIVNDGALVDFTGCGRWWVGLFAGVPGRAFHIWDCNSEETTFVGGTLTDPEAVMG 280
*******************************..66*************************************************************** PP
SAP 295 WhmlteltelvGrvrvteretavaCtslrlvvfdlrnqgvvlreeeer.rGlivssldasneayvvvdsrGvatvrrvenleevcrfrvrg.aqrgvl 390
Wh+ltelt+++Gr+r++++etavaCt++r++v+dlrnqgv+++e+ee+ rGliv+++da++eayv++dsrG+a+vrrv++ ++vc+frv+g aqr+v+
AT5G35770.1 281 WHTLTELTTSLGRLRISGNETAVACTRWRIMVIDLRNQGVIIGEDEEQrRGLIVTGFDANDEAYVRLDSRGNASVRRVNTQQTVCEFRVSGaAQRRVM 378
******************************************99888779*****************************************9****** PP
SAP 391 gCvnggyalvyaggvlrvWeiekkegylyslrervgevnalvaddrhvavsss....dgtihlldfga 454
gCvn+ +al++agg++rvWe+e+ e ylys+rervgev+a+vaddrhvav+s+ +++ihl+dfga
AT5G35770.1 379 GCVNRLHALMCAGGIMRVWEVERGE-YLYSIRERVGEVDAIVADDRHVAVASAsstaQSIIHLWDFGA 445
***********************77.***********************98875666899*******8 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0009554 | Biological Process | megasporogenesis |
| GO:0009908 | Biological Process | flower development |
| GO:0030154 | Biological Process | cell differentiation |
| GO:0030163 | Biological Process | protein catabolic process |
| GO:0046622 | Biological Process | positive regulation of organ growth |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| GO:0005515 | Molecular Function | protein binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 446 aa
Download sequence Send
to blast |
MSTSSSSSDN GAGGSGGVFE APSPSRPRRG ANDVWPEPFL ESLAVQVAVN ASTSAGLLAA 60
APALANVFRV CTTWHAVSRS DHLWQLLSRQ VWARTHLMHD TWRDEFIYRH RTARNFRTRT 120
HTYFTLQFDP SDVDEPDSLS CRCLTLSDLY LAAGFADGTV RLFLLNNRLH VRTLRPPLRD 180
RFGRFSRAVS GIVISDSRLT FATMDGDIHV AEIDGVGHTR TAYAGDIVND GALVDFTGCG 240
RWWVGLFAGV PGRAFHIWDC NSEETTFVGG TLTDPEAVMG WHTLTELTTS LGRLRISGNE 300
TAVACTRWRI MVIDLRNQGV IIGEDEEQRR GLIVTGFDAN DEAYVRLDSR GNASVRRVNT 360
QQTVCEFRVS GAAQRRVMGC VNRLHALMCA GGIMRVWEVE RGEYLYSIRE RVGEVDAIVA 420
DDRHVAVASA SSTAQSIIHL WDFGAL
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | TISSUE SPECIFICITY: Expressed in inflorescence and floral meristems, young floral organ primordia, and later in ovule primordia. |
| Functional Description ? help
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| Source |
Description |
| TAIR | A recessive mutation in the Arabidopsis STERILE APETALA (SAP) causes severe aberrations in inflorescence and flower and ovule development. |
| UniProt | Transcriptional regulator involved in the specification of floral identity. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in the external flower organs in association with APETALA2 and other repressors. Is required to maintain floral meristem identity in concert with AGAMOUS. Interacts also with APETALA2 to ensure the normal development of ovule. |
| Function -- GeneRIF ? help
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- SAP controls organ size by targeting PEAROD1 and PEAPOD2 proteins for degradation in Arabidopsis thaliana.
[PMID: 27048938] - SAP acts in a common pathway with KIX8/9 and PPD to control organ growth by regulating meristemoid cell proliferation. Thus, these findings reveal a molecular mechanism by which SAP targets the KIX-PPD repressor complex for degradation to regulate meristemoid cell proliferation and organ size.
[PMID: 29401459]
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| Publications
? help Back to Top |
- Byzova MV, et al.
Arabidopsis STERILE APETALA, a multifunctional gene regulating inflorescence, flower, and ovule development.
Genes Dev., 1999. 13(8): p. 1002-14
[PMID:10215627] - Krizek BA,Prost V,Macias A
AINTEGUMENTA promotes petal identity and acts as a negative regulator of AGAMOUS.
Plant Cell, 2000. 12(8): p. 1357-66
[PMID:10948255] - Durfee T, et al.
The F-box-containing protein UFO and AGAMOUS participate in antagonistic pathways governing early petal development in Arabidopsis.
Proc. Natl. Acad. Sci. U.S.A., 2003. 100(14): p. 8571-6
[PMID:12826617] - Jack T
Molecular and genetic mechanisms of floral control.
Plant Cell, 2004. 16 Suppl: p. S1-17
[PMID:15020744] - Ascencio-Ib
Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
Plant Physiol., 2008. 148(1): p. 436-54
[PMID:18650403] - Shatil-Cohen A,Attia Z,Moshelion M
Bundle-sheath cell regulation of xylem-mesophyll water transport via aquaporins under drought stress: a target of xylem-borne ABA?
Plant J., 2011. 67(1): p. 72-80
[PMID:21401747] - Jin J, et al.
An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
Mol. Biol. Evol., 2015. 32(7): p. 1767-73
[PMID:25750178] - Wang Z, et al.
SCF(SAP) controls organ size by targeting PPD proteins for degradation in Arabidopsis thaliana.
Nat Commun, 2016. 7: p. 11192
[PMID:27048938] - Li N, et al.
STERILE APETALA modulates the stability of a repressor protein complex to control organ size in Arabidopsis thaliana.
PLoS Genet., 2018. 14(2): p. e1007218
[PMID:29401459]
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