PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G21120.1
Common NameEIL2, T10F18.150
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family EIL
Protein Properties Length: 518aa    MW: 59185.7 Da    PI: 6.0395
Description ETHYLENE-INSENSITIVE3-like 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G21120.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3404.21.6e-123484081354
                  XXXXXXXXXXXXXXXXXXXXXXX..XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
         EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaatgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsLraWWkek 98 
                  eel+k+ w+d+++lkrlke+ k+ l+++     ++++++  e++++++m +aQDgiLkYM k+me ++aqGfvYgi+ e+gk+v g+sd+Lr+WWk+k
  AT5G21120.1  48 EELEKKIWRDKQRLKRLKEMAKNGLGTRLL--LKQQHDDFPEHSSKRTMYKAQDGILKYMSKTMERYKAQGFVYGIVLENGKTVAGSSDNLREWWKDK 143
                  8**********************9977775..778899************************************************************ PP

                  XXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHHHHT--TT--...-- CS
         EIN3  99 vefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwgelglskdqg..tpp 194
                  v+fdrngpaai+k+q + ++++g++s +  + s+ ++l elqDTtlg+LLsal+ hc+ppqrrfplekgv+pPWWPtGke+ww++l+l+ d +  +pp
  AT5G21120.1 144 VRFDRNGPAAIIKHQRDINLSDGSDSGSEVGDSTAQKLLELQDTTLGALLSALFPHCNPPQRRFPLEKGVTPPWWPTGKEDWWDQLSLPVDFRgvPPP 241
                  ********************9999999888******************************************************************** PP

                  ---GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXX..XX.......XXXXXXXXXXXXXXXXXX CS
         EIN3 195 ykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsah..ss.......slrkqspkvtlsceqked 283
                  ykkphdlkk wk++vL  vi+hm+ +i++i +l+r+s++lq+km+++e + +l+ l +e+++++++ ++  ++         + ++p+v + +++++d
  AT5G21120.1 242 YKKPHDLKKLWKIGVLIGVIRHMASDISNIPNLVRRSRSLQEKMTSREGALWLAALYREKAIVDQIAMSreNNntsnflvPATGGDPDVLFPESTDYD 339
                  *******************************************************************99652267777765556************** PP

                  XX...XXXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX......XXXXXXX.XXXXXXXXXXXXXXXXX CS
         EIN3 284 ve...gkkeskikhvqavkttagfpvvrkrkkkpsesakvsskevsrtcqssqfrgsetelifadknsisqney 354
                  ve   g+++++    q  + ++++++v krk +++  + ++ +    tc++s +++s+++++f d+n ++++++
  AT5G21120.1 340 VEligGTHRTN---QQYPEFENNYNCVYKRKFEEDFGMPMHPT--LLTCENSLCPYSQPHMGFLDRNLRENHQM 408
                  **765555555...566666779********999999999877..89*************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048733.1E-11648301No hitNo description
Gene3DG3DSA:1.10.3180.101.9E-59173309IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167682.48E-53179304IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
Sequence ? help Back to Top
Protein Sequence    Length: 518 aa     Download sequence    Send to blast
MDMYNNNIGM FRSLVCSSAP PFTEGHMCSD SHTALCDDLS SDEEMEIEEL EKKIWRDKQR  60
LKRLKEMAKN GLGTRLLLKQ QHDDFPEHSS KRTMYKAQDG ILKYMSKTME RYKAQGFVYG  120
IVLENGKTVA GSSDNLREWW KDKVRFDRNG PAAIIKHQRD INLSDGSDSG SEVGDSTAQK  180
LLELQDTTLG ALLSALFPHC NPPQRRFPLE KGVTPPWWPT GKEDWWDQLS LPVDFRGVPP  240
PYKKPHDLKK LWKIGVLIGV IRHMASDISN IPNLVRRSRS LQEKMTSREG ALWLAALYRE  300
KAIVDQIAMS RENNNTSNFL VPATGGDPDV LFPESTDYDV ELIGGTHRTN QQYPEFENNY  360
NCVYKRKFEE DFGMPMHPTL LTCENSLCPY SQPHMGFLDR NLRENHQMTC PYKVTSFYQP  420
TKPYGMTGLM VPCPDYNGMQ QQVQSFQDQF NHPNDLYRPK APQRGNDDLV EDLNPSPSTL  480
NQNLGLVLPT DFNGGEETVG TENNLHNQGQ ELPTSWIQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A5e-521763071130Protein ETHYLENE INSENSITIVE 3
4zds_B5e-521763071130Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO22249280.0
Genevisible246023_at0.0
Expression AtlasAT5G21120-
AtGenExpressAT5G21120-
ATTED-IIAT5G21120-
Functional Description ? help Back to Top
Source Description
TAIRethylene-insensitive3-like2 (EIL2)
UniProtProbable transcription factor acting as a positive regulator in the ethylene response pathway. Could bind the primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter. {ECO:0000269|PubMed:9215635, ECO:0000269|PubMed:9851977}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G21120.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT3G23240(A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDethylene
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G14920
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G21120
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0693250.0AC069325.6 Genomic Sequence For Arabidopsis thaliana Clone T10F18 From Chromosome V, complete sequence.
GenBankAC1409770.0AC140977.1 Arabidopsis thaliana chromosome 5 BAC F13M11 genomic sequence, complete sequence.
GenBankAF0042140.0AF004214.1 Arabidopsis thaliana ethylene-insensitive3-like2 (EIL2) mRNA, complete cds.
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001332194.10.0ETHYLENE-INSENSITIVE3-like 2
SwissprotO231150.0EIL2_ARATH; ETHYLENE INSENSITIVE 3-like 2 protein
TrEMBLA0A1P8BG660.0A0A1P8BG66_ARATH; ETHYLENE-INSENSITIVE3-like 2
STRINGAT5G21120.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM147191621
Representative plantOGRP5631682
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Alonso JM, et al.
    Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2003. 100(5): p. 2992-7
    [PMID:12606727]
  3. Barry CS,Giovannoni JJ
    Ripening in the tomato Green-ripe mutant is inhibited by ectopic expression of a protein that disrupts ethylene signaling.
    Proc. Natl. Acad. Sci. U.S.A., 2006. 103(20): p. 7923-8
    [PMID:16682641]
  4. Binder BM, et al.
    The Arabidopsis EIN3 binding F-Box proteins EBF1 and EBF2 have distinct but overlapping roles in ethylene signaling.
    Plant Cell, 2007. 19(2): p. 509-23
    [PMID:17307926]
  5. Van der Ent S, et al.
    MYB72 is required in early signaling steps of rhizobacteria-induced systemic resistance in Arabidopsis.
    Plant Physiol., 2008. 146(3): p. 1293-304
    [PMID:18218967]
  6. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  7. Wawrzyńska A,Lewandowska M,Sirko A
    Nicotiana tabacum EIL2 directly regulates expression of at least one tobacco gene induced by sulphur starvation.
    J. Exp. Bot., 2010. 61(3): p. 889-900
    [PMID:20018902]
  8. Luo J, et al.
    A DELLA gene, RhGAI1, is a direct target of EIN3 and mediates ethylene-regulated rose petal cell expansion via repressing the expression of RhCesA2.
    J. Exp. Bot., 2013. 64(16): p. 5075-84
    [PMID:24014864]
  9. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
    [PMID:25118255]
  10. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  11. Chao Q, et al.
    Activation of the ethylene gas response pathway in Arabidopsis by the nuclear protein ETHYLENE-INSENSITIVE3 and related proteins.
    Cell, 1997. 89(7): p. 1133-44
    [PMID:9215635]
  12. Solano R,Stepanova A,Chao Q,Ecker JR
    Nuclear events in ethylene signaling: a transcriptional cascade mediated by ETHYLENE-INSENSITIVE3 and ETHYLENE-RESPONSE-FACTOR1.
    Genes Dev., 1998. 12(23): p. 3703-14
    [PMID:9851977]