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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT5G17800.1 |
| Common Name | AtMYB56, MYB56 |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
MYB |
| Protein Properties |
Length: 323aa MW: 36892.1 Da PI: 9.7415 |
| Description |
myb domain protein 56 |
| Gene Model |
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| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | Myb_DNA-binding | 50.7 | 4e-16 | 93 | 138 | 1 | 47 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47
rg W + Ed +l+++v+q+G+ +W++I++++ gR++k+c++rw++
AT5G17800.1 93 RGHWRPTEDAKLKELVAQFGPQNWNLISNHLL-GRSGKSCRLRWFNQ 138
899****************************9.***********996 PP
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| 2 | Myb_DNA-binding | 52.4 | 1.3e-16 | 146 | 188 | 2 | 46 |
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
++T+eE+ +l+ a++ +G++ W++I+r ++ gRt++ +k++w+
AT5G17800.1 146 RAFTEEEEFRLLAAHRAYGNK-WALISRLFP-GRTDNAVKNHWHV 188
689******************.*********.***********96 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006357 | Biological Process | regulation of transcription from RNA polymerase II promoter |
| GO:0030154 | Biological Process | cell differentiation |
| GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
| GO:0051782 | Biological Process | negative regulation of cell division |
| GO:0071367 | Biological Process | cellular response to brassinosteroid stimulus |
| GO:0005634 | Cellular Component | nucleus |
| GO:0000981 | Molecular Function | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| GO:0001046 | Molecular Function | core promoter sequence-specific DNA binding |
| GO:0001135 | Molecular Function | transcription factor activity, RNA polymerase II transcription factor recruiting |
| Sequence ? help Back to Top |
| Protein Sequence Length: 323 aa
Download sequence Send
to blast |
MNPNLLEKDL RGKETTNGSI RYKEANNFRS LPNSHTAACK TSLNNPSISR NHPHNKSASV 60
LESEDEHGNE RGENEKSLRM RGKSGINTKV CSRGHWRPTE DAKLKELVAQ FGPQNWNLIS 120
NHLLGRSGKS CRLRWFNQLD PRINKRAFTE EEEFRLLAAH RAYGNKWALI SRLFPGRTDN 180
AVKNHWHVIM ARRTRESQRQ RQQPPPTLSR DAEMTVSSSC RYNQGKFINE EDDDDDVSAV 240
STCTTELSLT PPSSAYQPRF FNYDSTLASG KDGQCVQRAE VNGIYGKKMD HQNHHTISVS 300
ERKVEMKMRS GYYYFDFLGV GAS
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: Expressed in developing seeds. {ECO:0000269|PubMed:23911125}. |
| Uniprot | TISSUE SPECIFICITY: Mostly expressed in flowers (at protein level) and siliques, and, to a lower extent, in roots, stems and leaves (PubMed:25343985). Expressed in embryos (e.g. heart and torpedo stages) and cotyledons, and, at low levels, in roots and inflorescence (PubMed:23911125). Accumulates specifically in root apical meristem quiescent center (QC) and vascular initial cells (PubMed:16581911, PubMed:24981610). {ECO:0000269|PubMed:16581911, ECO:0000269|PubMed:23911125, ECO:0000269|PubMed:24981610, ECO:0000269|PubMed:25343985}. |
| Functional Description ? help
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| Source |
Description |
| TAIR | Member of the R2R3 factor gene family. |
| UniProt | Acts as a cell-specific local repressor of quiescent center (QC) self-renewal by cell divisions in the primary root. Counteracts brassinosteroid (BR)-mediated cell division in the QC cells (PubMed:24981610). Regulates maternally seed size, especially before the heart stage, promoting both endothelial cells expansion and cell number in the outer integument layer of the seed coat (PubMed:23911125). Modulates the expression of genes involved in cell wall metabolism such as cell division and expansion (PubMed:23911125, PubMed:24981610). Negative regulator of flowering via the repression of FT transcription (PubMed:25343985). {ECO:0000269|PubMed:23911125, ECO:0000269|PubMed:24981610, ECO:0000269|PubMed:25343985}. |
| Function -- GeneRIF ? help
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- MYB56 represents an unknown pathway for positively controlling the seed size.
[PMID: 23911125]
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| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Levels follow a circadian cycle with a progressive decrease during the day time (at protein level) (PubMed:25343985). Down-regulated by brassinosteroids (BRs) in a dose- and time-dependent manner. Repressed by BES1. Auto-activation of expression (PubMed:24981610). Targeted to 26S proteasomal degradation by the CULLIN3 (CUL3)-based E3 ligases CRL3(BPMs) (PubMed:25343985). {ECO:0000269|PubMed:24981610, ECO:0000269|PubMed:25343985}. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AK176193 | 0.0 | AK176193.1 Arabidopsis thaliana mRNA for MYB56 R2R3-MYB factor family member, complete cds, clone: RAFL23-05-P12. |
| GenBank | AK176277 | 0.0 | AK176277.1 Arabidopsis thaliana mRNA for MYB56 R2R3-MYB factor family member, complete cds, clone: RAFL23-20-A13. |
| GenBank | AY519627 | 0.0 | AY519627.1 Arabidopsis thaliana MYB transcription factor (At5g17800) mRNA, complete cds. |
| Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Stracke R,Werber M,Weisshaar B
The R2R3-MYB gene family in Arabidopsis thaliana.
Curr. Opin. Plant Biol., 2001. 4(5): p. 447-56
[PMID:11597504] - Nawy T, et al.
Transcriptional profile of the Arabidopsis root quiescent center.
Plant Cell, 2005. 17(7): p. 1908-25
[PMID:15937229] - Nakayama N, et al.
Gene trap lines define domains of gene regulation in Arabidopsis petals and stamens.
Plant Cell, 2005. 17(9): p. 2486-506
[PMID:16055634] - Yanhui C, et al.
The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.
Plant Mol. Biol., 2006. 60(1): p. 107-24
[PMID:16463103] - Lee JY, et al.
Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots.
Proc. Natl. Acad. Sci. U.S.A., 2006. 103(15): p. 6055-60
[PMID:16581911] - Mace DL, et al.
Quantification of transcription factor expression from Arabidopsis images.
Bioinformatics, 2006. 22(14): p. e323-31
[PMID:16873489] - Day RC,Herridge RP,Ambrose BA,Macknight RC
Transcriptome analysis of proliferating Arabidopsis endosperm reveals biological implications for the control of syncytial division, cytokinin signaling, and gene expression regulation.
Plant Physiol., 2008. 148(4): p. 1964-84
[PMID:18923020] - Zhang Y,Liang W,Shi J,Xu J,Zhang D
MYB56 encoding a R2R3 MYB transcription factor regulates seed size in Arabidopsis thaliana.
J Integr Plant Biol, 2013. 55(11): p. 1166-78
[PMID:23911125] - Vilarrasa-Blasi J, et al.
Regulation of plant stem cell quiescence by a brassinosteroid signaling module.
Dev. Cell, 2014. 30(1): p. 36-47
[PMID:24981610] - Chen L,Bernhardt A,Lee J,Hellmann H
Identification of Arabidopsis MYB56 as a novel substrate for CRL3BPM E3 ligases.
Mol Plant, 2015.
[PMID:25343985] - Chen L,Bernhardt A,Lee J,Hellmann H
Identification of Arabidopsis MYB56 as a novel substrate for CRL3(BPM) E3 ligases.
Mol Plant, 2015. 8(2): p. 242-50
[PMID:25618823] - Frigola D,Caño-Delgado AI,Ibañes M
Methods for Modeling Brassinosteroid-Mediated Signaling in Plant Development.
Methods Mol. Biol., 2017. 1564: p. 103-120
[PMID:28124249] - Espinosa-Ruiz A, et al.
TOPLESS mediates brassinosteroid control of shoot boundaries and root meristem development in Arabidopsis thaliana.
Development, 2017. 144(9): p. 1619-1628
[PMID:28320734] - Jeong CY, et al.
AtMyb56 Regulates Anthocyanin Levels via the Modulation of AtGPT2 Expression in Response to Sucrose in Arabidopsis.
Mol. Cells, 2018. 41(4): p. 351-361
[PMID:29487277]
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