PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G05410.2
Common NameDREB2, DREB2A
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 302aa    MW: 33982.6 Da    PI: 6.7618
Description DRE-binding protein 2A
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G05410.2genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP259.58e-1977127155
          AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                  + ++GVr++  +g+WvAeIr+p   + r  r +lg+f ta+eAa a+++a+k+++g
  AT5G05410.2  77 CSFRGVRQRI-WGKWVAEIREP---N-RgSRLWLGTFPTAQEAASAYDEAAKAMYG 127
                  579****998.**********8...3.35************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008471.2E-1377127IPR001471AP2/ERF domain
CDDcd000187.03E-3177135No hitNo description
SMARTSM003803.5E-3878141IPR001471AP2/ERF domain
PROSITE profilePS5103221.79978135IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.107.8E-3178136IPR001471AP2/ERF domain
SuperFamilySSF541717.85E-2179136IPR016177DNA-binding domain
PRINTSPR003671.9E-97990IPR001471AP2/ERF domain
PRINTSPR003671.9E-9101117IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0010224Biological Processresponse to UV-B
GO:0010286Biological Processheat acclimation
GO:0042542Biological Processresponse to hydrogen peroxide
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000084anatomyplant sperm cell
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025195anatomypollen tube cell
PO:0025281anatomypollen
PO:0001017developmental stageM germinated pollen stage
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 302 aa     Download sequence    Send to blast
MAVYDQSGDR NRTQIDTSRK RKSRSRGDGT TVAERLKRWK EYNETVEEVS TKKRKVPAKG  60
SKKGCMKGKG GPENSRCSFR GVRQRIWGKW VAEIREPNRG SRLWLGTFPT AQEAASAYDE  120
AAKAMYGPLA RLNFPRSDAS EVTSTSSQSE VCTVETPGCV HVKTEDPDCE SKPFSGGVEP  180
MYCLENGAEE MKRGVKADKH WLSEFEHNYW SDILKEKEKQ KEQGIVETCQ QQQQDSLSVA  240
DYGLNQDRYP GNSVANGSYR PESQQSGFDP LQSLNYGIPP FQLEGKDGNG FFDDLSYLDL  300
EN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A3e-1679135360ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
11722SRKRKS
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.252470.0leaf| root| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible250781_at1e-150
Expression AtlasAT5G05410-
AtGenExpressAT5G05410-
ATTED-IIAT5G05410-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed preferentially in roots and stems, and at a lower level in leaves. {ECO:0000269|PubMed:10809011, ECO:0000269|PubMed:9707537}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a transcription factor that specifically binds to DRE/CRT cis elements (responsive to drought and low-temperature stress). Belongs to the DREB subfamily A-2 of ERF/AP2 transcription factor family (DREB2A). There are eight members in this subfamily including DREB2B. The protein contains one AP2 domain. Overexpression of transcriptional activation domain of DREB2A resulted in significant drought stress tolerance but only slight freezing tolerance in transgenic Arabidopsis plants. Microarray and RNA gel blot analyses revealed that DREB2A regulates expression of many water stressinducible genes.
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. {ECO:0000269|PubMed:11798174}.
Function -- GeneRIF ? help Back to Top
  1. The region between DREB2A residues 136 and 165 plays a role in the stability of this protein in the nucleus, which is important for protein activation.
    [PMID: 16617101]
  2. Functions in both water-stress and heat shock-stress responses.
    [PMID: 17030801]
  3. Altogether these data demonstrate that HsfA3 is transcriptionally controlled by DREB2A and important for the establishment of thermotolerance.
    [PMID: 17999647]
  4. These results indicate that HsfA3 regulates expression of many heat-inducible genes in the transcriptional cascade downstream of the DREB2A stress-regulatory system and functions in acquisition of thermotolerance under the control of the DREB2A cascade.
    [PMID: 18261981]
  5. Overexpression of DREB1A improves stress tolerance to both freezing and dehydration while overexpression of an active form of DREB2A results in significant stress tolerance to dehydration but only slight tolerance to freezing.
    [PMID: 19502356]
  6. These results suggest that in addition to an abscissic acid (ABA)-independent pathway, the ABA-dependent pathway plays a positive role in the osmotic stress-responsive expression of DREB2A.
    [PMID: 22025559]
  7. In addition RCD1 is rapidly degraded during heat stress, thus our results suggest that removal of RCD1 protein or the loss of the interaction domain in DREB2A appears to be required for proper DREB2A function under stress conditions.
    [PMID: 22150398]
  8. Functional interactions between Dreb2a and Med25 induce conformational changes which in turn cause changes in their binding affinity.
    [PMID: 22447446]
  9. GRF7 binds to a region of the DREB2A promoter and represses its activity.
    [PMID: 22942381]
  10. The stabilization of DREB2A is important but not sufficient to induce target gene expression; further activation processes are required.
    [PMID: 24376497]
  11. The stress-inducible expression of Arabidopsis thaliana DREB2A CA in transgenic sugarcane led to the up-regulation of genes involved in plant response to drought stress.
    [PMID: 24656336]
  12. transcriptional responses of the OPDA-responsive genes HsfA2 and DREB2A to the protein synthesis inhibitor cycloheximide and to the HSP90 inhibitor geldanamycin
    [PMID: 25036962]
  13. In this study, an attempt has been made to improve CT in drought hardy crop, peanut (Arachis hypogaea L., cv. TMV2) by co-expressing stress-responsive transcription factors (TFs), AtDREB2A, AtHB7 and AtABF3, associated with downstream gene expression
    [PMID: 25474740]
  14. DPB3-1 associates with NF-YA and NF-YB subunits to enhance heat stress-inducible gene expression during heat stress responses in cooperation with DREB2A.
    [PMID: 25490919]
  15. NMR spectroscopy further demonstrated that DREB2A underwent coupled folding and binding with alpha-helix formation upon interaction with RCD1, whereas peptides from ANAC013 and ANAC046 formed different structures or were fuzzy in the complexes.
    [PMID: 27881680]
  16. Genetic analysis indicated that the depletion of BTB/POZ AND MATH DOMAIN protein expression conferred enhanced thermotolerance via DREB2A stabilization
    [PMID: 28923951]
  17. These observations suggest that inhibition of NRD phosphorylation stabilizes and activates DREB2A in response to heat stress to enhance plant thermotolerance.
    [PMID: 30487287]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G05410.2
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By high-salt and drought stresses. {ECO:0000269|PubMed:10809011, ECO:0000269|PubMed:11798174, ECO:0000269|PubMed:9707537}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G01470(A), AT1G52690(A), AT2G41190(A), AT2G42540(A), AT3G12580(A), AT3G17520(A), AT3G50970(A), AT4G33720(A), AT5G52300(A), AT5G52310(A), AT5G59720(A)
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G45249
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G05410
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0077900.0AB007790.1 Arabidopsis thaliana mRNA for DREB2A, complete cds.
GenBankAB0106920.0AB010692.1 Arabidopsis thaliana genomic DNA, chromosome 5, TAC clone:K18I23.
GenBankAB0165700.0AB016570.1 Arabidopsis thaliana DREB2A gene, complete cds.
GenBankAY0639720.0AY063972.1 Arabidopsis thaliana putative DREB2A protein (At5g05410) mRNA, complete cds.
GenBankAY5360560.0AY536056.1 Fraxinus pennsylvanica dehydration responsive element binding protein (DREB2A) mRNA, complete cds.
GenBankAY6462230.0AY646223.1 Oryza sativa (indica cultivar-group) DREB-like protein gene, complete cds.
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001031837.10.0DRE-binding protein 2A
SwissprotO821320.0DRE2A_ARATH; Dehydration-responsive element-binding protein 2A
TrEMBLA8MSB10.0A8MSB1_ARATH; DRE-binding protein 2A
STRINGAT5G05410.10.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Nakashima K, et al.
    Organization and expression of two Arabidopsis DREB2 genes encoding DRE-binding proteins involved in dehydration- and high-salinity-responsive gene expression.
    Plant Mol. Biol., 2000. 42(4): p. 657-65
    [PMID:10809011]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Xiong L,Ishitani M,Lee H,Zhu JK
    The Arabidopsis LOS5/ABA3 locus encodes a molybdenum cofactor sulfurase and modulates cold stress- and osmotic stress-responsive gene expression.
    Plant Cell, 2001. 13(9): p. 2063-83
    [PMID:11549764]
  4. Sakuma Y, et al.
    DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression.
    Biochem. Biophys. Res. Commun., 2002. 290(3): p. 998-1009
    [PMID:11798174]
  5. Hao D,Yamasaki K,Sarai A,Ohme-Takagi M
    Determinants in the sequence specific binding of two plant transcription factors, CBF1 and NtERF2, to the DRE and GCC motifs.
    Biochemistry, 2002. 41(13): p. 4202-8
    [PMID:11914065]
  6. Narusaka Y, et al.
    Interaction between two cis-acting elements, ABRE and DRE, in ABA-dependent expression of Arabidopsis rd29A gene in response to dehydration and high-salinity stresses.
    Plant J., 2003. 34(2): p. 137-48
    [PMID:12694590]
  7. Boyce JM, et al.
    The sfr6 mutant of Arabidopsis is defective in transcriptional activation via CBF/DREB1 and DREB2 and shows sensitivity to osmotic stress.
    Plant J., 2003. 34(4): p. 395-406
    [PMID:12753580]
  8. Ulm R, et al.
    Genome-wide analysis of gene expression reveals function of the bZIP transcription factor HY5 in the UV-B response of Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2004. 101(5): p. 1397-402
    [PMID:14739338]
  9. Sakuma Y, et al.
    Functional analysis of an Arabidopsis transcription factor, DREB2A, involved in drought-responsive gene expression.
    Plant Cell, 2006. 18(5): p. 1292-309
    [PMID:16617101]
  10. Egawa C, et al.
    Differential regulation of transcript accumulation and alternative splicing of a DREB2 homolog under abiotic stress conditions in common wheat.
    Genes Genet. Syst., 2006. 81(2): p. 77-91
    [PMID:16755132]
  11. Lim CJ, et al.
    Gene expression profiles during heat acclimation in Arabidopsis thaliana suspension-culture cells.
    J. Plant Res., 2006. 119(4): p. 373-83
    [PMID:16807682]
  12. Rosado A, et al.
    The Arabidopsis tetratricopeptide repeat-containing protein TTL1 is required for osmotic stress responses and abscisic acid sensitivity.
    Plant Physiol., 2006. 142(3): p. 1113-26
    [PMID:16998088]
  13. Sakuma Y, et al.
    Dual function of an Arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expression.
    Proc. Natl. Acad. Sci. U.S.A., 2006. 103(49): p. 18822-7
    [PMID:17030801]
  14. Agarwal P,Agarwal PK,Nair S,Sopory SK,Reddy MK
    Stress-inducible DREB2A transcription factor from Pennisetum glaucum is a phosphoprotein and its phosphorylation negatively regulates its DNA-binding activity.
    Mol. Genet. Genomics, 2007. 277(2): p. 189-98
    [PMID:17089163]
  15. Dai X, et al.
    Overexpression of an R1R2R3 MYB gene, OsMYB3R-2, increases tolerance to freezing, drought, and salt stress in transgenic Arabidopsis.
    Plant Physiol., 2007. 143(4): p. 1739-51
    [PMID:17293435]
  16. Qin F, et al.
    Regulation and functional analysis of ZmDREB2A in response to drought and heat stresses in Zea mays L.
    Plant J., 2007. 50(1): p. 54-69
    [PMID:17346263]
  17. Kant P,Kant S,Gordon M,Shaked R,Barak S
    STRESS RESPONSE SUPPRESSOR1 and STRESS RESPONSE SUPPRESSOR2, two DEAD-box RNA helicases that attenuate Arabidopsis responses to multiple abiotic stresses.
    Plant Physiol., 2007. 145(3): p. 814-30
    [PMID:17556511]
  18. Schramm F, et al.
    A cascade of transcription factor DREB2A and heat stress transcription factor HsfA3 regulates the heat stress response of Arabidopsis.
    Plant J., 2008. 53(2): p. 264-74
    [PMID:17999647]
  19. Tran LS, et al.
    Functional analysis of AHK1/ATHK1 and cytokinin receptor histidine kinases in response to abscisic acid, drought, and salt stress in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2007. 104(51): p. 20623-8
    [PMID:18077346]
  20. Chung S,Parish RW
    Combinatorial interactions of multiple cis-elements regulating the induction of the Arabidopsis XERO2 dehydrin gene by abscisic acid and cold.
    Plant J., 2008. 54(1): p. 15-29
    [PMID:18088305]
  21. Yoshida T, et al.
    Functional analysis of an Arabidopsis heat-shock transcription factor HsfA3 in the transcriptional cascade downstream of the DREB2A stress-regulatory system.
    Biochem. Biophys. Res. Commun., 2008. 368(3): p. 515-21
    [PMID:18261981]
  22. Safrany J, et al.
    Identification of a novel cis-regulatory element for UV-B-induced transcription in Arabidopsis.
    Plant J., 2008. 54(3): p. 402-14
    [PMID:18266923]
  23. Zhou QY, et al.
    Soybean WRKY-type transcription factor genes, GmWRKY13, GmWRKY21, and GmWRKY54, confer differential tolerance to abiotic stresses in transgenic Arabidopsis plants.
    Plant Biotechnol. J., 2008. 6(5): p. 486-503
    [PMID:18384508]
  24. Zhang X,Liu S,Takano T
    Two cysteine proteinase inhibitors from Arabidopsis thaliana, AtCYSa and AtCYSb, increasing the salt, drought, oxidation and cold tolerance.
    Plant Mol. Biol., 2008. 68(1-2): p. 131-43
    [PMID:18523728]
  25. Qin F, et al.
    Arabidopsis DREB2A-interacting proteins function as RING E3 ligases and negatively regulate plant drought stress-responsive gene expression.
    Plant Cell, 2008. 20(6): p. 1693-707
    [PMID:18552202]
  26. Wang Y, et al.
    Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.
    Plant Physiol., 2008. 148(3): p. 1201-11
    [PMID:18775970]
  27. Perera IY,Hung CY,Moore CD,Stevenson-Paulik J,Boss WF
    Transgenic Arabidopsis plants expressing the type 1 inositol 5-phosphatase exhibit increased drought tolerance and altered abscisic acid signaling.
    Plant Cell, 2008. 20(10): p. 2876-93
    [PMID:18849493]
  28. Maruyama K, et al.
    Metabolic pathways involved in cold acclimation identified by integrated analysis of metabolites and transcripts regulated by DREB1A and DREB2A.
    Plant Physiol., 2009. 150(4): p. 1972-80
    [PMID:19502356]
  29. Jaspers P, et al.
    Unequally redundant RCD1 and SRO1 mediate stress and developmental responses and interact with transcription factors.
    Plant J., 2009. 60(2): p. 268-79
    [PMID:19548978]
  30. Dong CJ,Liu JY
    The Arabidopsis EAR-motif-containing protein RAP2.1 functions as an active transcriptional repressor to keep stress responses under tight control.
    BMC Plant Biol., 2010. 10: p. 47
    [PMID:20230648]
  31. Lee SJ, et al.
    DREB2C interacts with ABF2, a bZIP protein regulating abscisic acid-responsive gene expression, and its overexpression affects abscisic acid sensitivity.
    Plant Physiol., 2010. 153(2): p. 716-27
    [PMID:20395451]
  32. Chen LT,Luo M,Wang YY,Wu K
    Involvement of Arabidopsis histone deacetylase HDA6 in ABA and salt stress response.
    J. Exp. Bot., 2010. 61(12): p. 3345-53
    [PMID:20519338]
  33. Li C, et al.
    TaCHP: a wheat zinc finger protein gene down-regulated by abscisic acid and salinity stress plays a positive role in stress tolerance.
    Plant Physiol., 2010. 154(1): p. 211-21
    [PMID:20639406]
  34. Inz
    A subcellular localization compendium of hydrogen peroxide-induced proteins.
    Plant Cell Environ., 2012. 35(2): p. 308-20
    [PMID:21443605]
  35. Suzuki N,Sejima H,Tam R,Schlauch K,Mittler R
    Identification of the MBF1 heat-response regulon of Arabidopsis thaliana.
    Plant J., 2011. 66(5): p. 844-51
    [PMID:21457365]
  36. Ying S, et al.
    Cloning and characterization of a maize SnRK2 protein kinase gene confers enhanced salt tolerance in transgenic Arabidopsis.
    Plant Cell Rep., 2011. 30(9): p. 1683-99
    [PMID:21638061]
  37. Rushton DL, et al.
    WRKY transcription factors: key components in abscisic acid signalling.
    Plant Biotechnol. J., 2012. 10(1): p. 2-11
    [PMID:21696534]
  38. Yoshida T, et al.
    Arabidopsis HsfA1 transcription factors function as the main positive regulators in heat shock-responsive gene expression.
    Mol. Genet. Genomics, 2011. 286(5-6): p. 321-32
    [PMID:21931939]
  39. Kim JS, et al.
    An ABRE promoter sequence is involved in osmotic stress-responsive expression of the DREB2A gene, which encodes a transcription factor regulating drought-inducible genes in Arabidopsis.
    Plant Cell Physiol., 2011. 52(12): p. 2136-46
    [PMID:22025559]
  40. Gaudinier A, et al.
    Enhanced Y1H assays for Arabidopsis.
    Nat. Methods, 2011. 8(12): p. 1053-5
    [PMID:22037706]
  41. Vainonen JP, et al.
    RCD1-DREB2A interaction in leaf senescence and stress responses in Arabidopsis thaliana.
    Biochem. J., 2012. 442(3): p. 573-81
    [PMID:22150398]
  42. Niu CF, et al.
    Wheat WRKY genes TaWRKY2 and TaWRKY19 regulate abiotic stress tolerance in transgenic Arabidopsis plants.
    Plant Cell Environ., 2012. 35(6): p. 1156-70
    [PMID:22220579]
  43. Wu A, et al.
    JUNGBRUNNEN1, a reactive oxygen species-responsive NAC transcription factor, regulates longevity in Arabidopsis.
    Plant Cell, 2012. 24(2): p. 482-506
    [PMID:22345491]
  44. Blomberg J, et al.
    Interactions between DNA, transcriptional regulator Dreb2a and the Med25 mediator subunit from Arabidopsis thaliana involve conformational changes.
    Nucleic Acids Res., 2012. 40(13): p. 5938-50
    [PMID:22447446]
  45. Liu X, et al.
    AtPP2CG1, a protein phosphatase 2C, positively regulates salt tolerance of Arabidopsis in abscisic acid-dependent manner.
    Biochem. Biophys. Res. Commun., 2012. 422(4): p. 710-5
    [PMID:22627139]

  46. MEDIATOR25 acts as an integrative hub for the regulation of jasmonate-responsive gene expression in Arabidopsis.
    Plant Physiol., 2012. 160(1): p. 541-55
    [PMID:22822211]
  47. Kim JS, et al.
    Arabidopsis growth-regulating factor7 functions as a transcriptional repressor of abscisic acid- and osmotic stress-responsive genes, including DREB2A.
    Plant Cell, 2012. 24(8): p. 3393-405
    [PMID:22942381]
  48. Renault H, et al.
    γ-Aminobutyric acid transaminase deficiency impairs central carbon metabolism and leads to cell wall defects during salt stress in Arabidopsis roots.
    Plant Cell Environ., 2013. 36(5): p. 1009-18
    [PMID:23148892]
  49. Mizoi J, et al.
    GmDREB2A;2, a canonical DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN2-type transcription factor in soybean, is posttranslationally regulated and mediates dehydration-responsive element-dependent gene expression.
    Plant Physiol., 2013. 161(1): p. 346-61
    [PMID:23151346]
  50. Li L, et al.
    Homologous HAP5 subunit from Picea wilsonii improved tolerance to salt and decreased sensitivity to ABA in transformed Arabidopsis.
    Planta, 2013. 238(2): p. 345-56
    [PMID:23703145]
  51. Zhao K, et al.
    Isolation and characterization of dehydration-responsive element-binding factor 2C (MsDREB2C) from Malus sieversii Roem.
    Plant Cell Physiol., 2013. 54(9): p. 1415-30
    [PMID:23757363]
  52. Djafi N, et al.
    The Arabidopsis DREB2 genetic pathway is constitutively repressed by basal phosphoinositide-dependent phospholipase C coupled to diacylglycerol kinase.
    Front Plant Sci, 2013. 4: p. 307
    [PMID:23964284]
  53. Morimoto K, et al.
    Stabilization of Arabidopsis DREB2A is required but not sufficient for the induction of target genes under conditions of stress.
    PLoS ONE, 2013. 8(12): p. e80457
    [PMID:24376497]
  54. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  55. Ruelland E,Djafi N,Zachowski A
    The phosphoinositide dependent-phospholipase C pathway differentially controls the basal expression of DREB1 and DREB2 genes.
    Plant Signal Behav, 2013. 8(10): p. doi: 10.4161/psb.26895
    [PMID:24494245]
  56. Reis RR, et al.
    Induced over-expression of AtDREB2A CA improves drought tolerance in sugarcane.
    Plant Sci., 2014. 221-222: p. 59-68
    [PMID:24656336]
  57. Cha JY, et al.
    NADPH-dependent thioredoxin reductase A (NTRA) confers elevated tolerance to oxidative stress and drought.
    Plant Physiol. Biochem., 2014. 80: p. 184-91
    [PMID:24792388]
  58. Aguilar X, et al.
    Interaction studies of the human and Arabidopsis thaliana Med25-ACID proteins with the herpes simplex virus VP16- and plant-specific Dreb2a transcription factors.
    PLoS ONE, 2014. 9(5): p. e98575
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  59. Sadhukhan A, et al.
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