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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT4G29940.2 |
| Common Name | PRHA |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
HB-PHD |
| Protein Properties |
Length: 769aa MW: 87582 Da PI: 4.6165 |
| Description |
pathogenesis related homeodomain protein A |
| Gene Model |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | Homeobox | 33.5 | 7e-11 | 462 | 506 | 9 | 53 |
HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHH CS
Homeobox 9 keqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRa 53
++ +e L ++F+++ ps++ r +LAk+l+L+ ++V WF+N R+
AT4G29940.2 462 RNAVEKLRQVFAETELPSKAVRDRLAKELSLDPEKVNKWFKNTRY 506
678999*************************************97 PP
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| 2 | PHD | 41.9 | 2.2e-14 | 192 | 247 | 1 | 51 |
SBTTTSS..TCTTSSEEEBS.SSSSEEETTTSTSSSSHHSHHSS..TBSSHHHHTT CS
PHD 1 rCkvCgk..sdeegelvlCd.gCkewfHlkClglkleseekpeg..ewlCeeCkek 51
+C+ C++ + +++++lCd +C+++fH+kCl+++le+e++p g w+C+ C++k
AT4G29940.2 192 FCAECNSreAFPDNDIILCDgTCNRAFHQKCLDPPLETESIPPGdqGWFCKFCDCK 247
6999***55455********56********************9999*******985 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006952 | Biological Process | defense response |
| GO:0009733 | Biological Process | response to auxin |
| GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| GO:0005515 | Molecular Function | protein binding |
| GO:0008270 | Molecular Function | zinc ion binding |
| GO:0043565 | Molecular Function | sequence-specific DNA binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 769 aa
Download sequence Send
to blast |
MEESETKGRI SQETDKACVS VERIGSTLLS SFVKKGKEVS NKRNSKQNKR KAEEELCSKS 60
RTKKYSRGWV RCEEMEEEKV KKTRKRKSKR QQKDNKVEVD DSLRLQRRTR YLLIKMKMQQ 120
NLIDAYATEG WKGQSREKIR PDKELERARK EILNCKLGLR DAIRQLDLLS SVGSMEEKVI 180
ASDGSIHHDH IFCAECNSRE AFPDNDIILC DGTCNRAFHQ KCLDPPLETE SIPPGDQGWF 240
CKFCDCKIEI IDTMNAQIGT HFPVDSNWQD IFNEEASLPI GSEATVNNEA DWPSDDSKDD 300
DYDPEMRENG GGNSSNVSGD GGGDNDEESI STSLSLSSDG VALSTGSWEG HRLSNMVEQC 360
ETSNEETVCG PRQRRTVDYT QLYYEMFGKD AVLQEQGSED EDWGPNDRRK RKRESDAGST 420
LVTMCESSKK DQDVVETLEQ SERDSVSVEN KGGRRRMFRL PRNAVEKLRQ VFAETELPSK 480
AVRDRLAKEL SLDPEKVNKW FKNTRYMALR NRKTESVKQP GDSKTVSGGD SGPEAVMENN 540
TETNEVQDTL DDTVPPGFDA TNQNILSPCN NNQEEFQQEN VSFPSPTDES QQYLEQNDSS 600
FVLVPHEKQS SEISLKTAVE ENETESKMMK EPHEELSREM SLKTAVEEKE TESKMMEEPH 660
DELNSEMSLS TAVEEKETGS KMTEESHEEL SNEMSLEEKE TGRKMTEEEE LEAVMEMLCR 720
TENKLLDVTQ RLDRFKTPKG RKKLGNSSSP LLEEDSVVYV PIAEIKEKR
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| Nucleic Localization
Signal ? help
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 |
| No. |
Start |
End |
Sequence |
| 1 | 82 | 87 | TRKRKS |
| 2 | 407 | 412 | RRKRKR |
| 3 | 452 | 459 | GRRRMFRL |
| Functional Description ? help
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| Source |
Description |
| TAIR | Homeodomain protein (PRHA). Expression of the gene differs in various vegetative and floral plant tissues and is positively influenced by the phytohormone auxin. It is often associated with regions of developing vascular tissue. The prha promoter is highly responsive to the synthetic auxin, naphthalene acetic acid, in transient assays using tobacco protoplasts. The PRHA protein has the capacity to bind to TAATTG core sequence elements but requires additional adjacent bases for high-affinity binding. |
| UniProt | Specifically binds to the fungal elicitor-responsive DNA element, 5'-CTAATTGTTTA-3', of the gene PR2 promoter. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: By pathogen infection. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | ATHPRHA | 0.0 | L21991.1 Arabidopsis thaliana homeodomain protein (PRHA) mRNA, complete cds. |
| Publications
? help Back to Top |
- Halbach T,Scheer N,Werr W
Transcriptional activation by the PHD finger is inhibited through an adjacent leucine zipper that binds 14-3-3 proteins.
Nucleic Acids Res., 2000. 28(18): p. 3542-50
[PMID:10982874] - Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Menges M,Hennig L,Gruissem W,Murray JA
Cell cycle-regulated gene expression in Arabidopsis.
J. Biol. Chem., 2002. 277(44): p. 41987-2002
[PMID:12169696] - Ding Y, et al.
Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
BMC Plant Biol., 2013. 13: p. 229
[PMID:24377444] - Korfhage U,Trezzini GF,Meier I,Hahlbrock K,Somssich IE
Plant homeodomain protein involved in transcriptional regulation of a pathogen defense-related gene.
Plant Cell, 1994. 6(5): p. 695-708
[PMID:7913642] - Plesch G,Störmann K,Torres JT,Walden R,Somssich IE
Developmental and auxin-induced expression of the Arabidopsis prha homeobox gene.
Plant J., 1997. 12(3): p. 635-47
[PMID:9351248] - Cormack RS,Hahlbrock K,Somssich IE
Isolation of putative plant transcriptional coactivators using a modified two-hybrid system incorporating a GFP reporter gene.
Plant J., 1998. 14(6): p. 685-92
[PMID:9681033]
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