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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT4G24150.1 |
| Common Name | AtGRF8, GRF8, T19F6.5 |
| Organism |
|
| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
GRF |
| Protein Properties |
Length: 493aa MW: 54608.7 Da PI: 6.9262 |
| Description |
growth-regulating factor 8 |
| Gene Model |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | WRC | 75.4 | 6.1e-24 | 244 | 287 | 2 | 45 |
WRC 2 aepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45
ep+rC+RtDGKkWRCsr+v++++k+CErH h++r rsrk++e+
AT4G24150.1 244 LEPWRCKRTDGKKWRCSRNVIPDQKYCERHTHKSRPRSRKHVES 287
69***************************************997 PP
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| 2 | QLQ | 52.7 | 1.3e-18 | 149 | 183 | 2 | 36 |
QLQ 2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiq 36
aF+ aQ+++L++Q +yKy++a++PvPpeLl + +
AT4G24150.1 149 AFSEAQWHELERQRNIYKYMMASVPVPPELLTPFP 183
8******************************9865 PP
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| Sequence ? help Back to Top |
| Protein Sequence Length: 493 aa
Download sequence Send
to blast |
MRMLLGIPYV DKSVLSNSVL ERGKQDKSKL LLVDKCHYEL DVEERKEDFV GGFGFGVVEN 60
SHKDVMVLPH HHYYPSYSSP SSSSLCYCSA GVSDPMFSVS SNQAYTSSHS GMFTPAGSGS 120
AAVTVADPFF SLSSSGEMRR SMNEDAGAAF SEAQWHELER QRNIYKYMMA SVPVPPELLT 180
PFPKNHQSNT NPDVDTYRSG MFSIYADYKN LPLSMWMTVT VAVATGGSLQ LGIASSASNN 240
TADLEPWRCK RTDGKKWRCS RNVIPDQKYC ERHTHKSRPR SRKHVESSHQ SSHHNDIRTA 300
KNDTSQLVRT YPQFYGQPIS QIPVLSTLPS ASSPYDHHRG LRWFTKEDDA IGTLNPETQE 360
AVQLKVGSSR ELKRGFDYDL NFRQKEPIVD QSFGALQGLL SLNQTPQHNQ ETRQFVVEGK 420
QDEAMGSSLT LSMAGGGMEE TEGTNQHQWV SHEGPSWLYS TTPGGPLAEA LCLGVSNNPS 480
SSTTTSSCSR SSS
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | TISSUE SPECIFICITY: Predominantly expressed in shoot tips and flowers. {ECO:0000269|PubMed:12974814}. |
| Functional Description ? help
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| Source |
Description |
| TAIR | Growth regulating factor encoding transcription activator. One of the nine members of a GRF gene family, containing nuclear targeting domain. Involved in leaf development and expressed in shoot and flower. |
| UniProt | Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000250}. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269|PubMed:15200956, ECO:0000269|PubMed:19453503}. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AL109619 | 0.0 | AL109619.1 Arabidopsis thaliana DNA chromosome 4, BAC clone T19F6, partial sequence (ESSA project). |
| GenBank | AL161561 | 0.0 | AL161561.2 Arabidopsis thaliana DNA chromosome 4, contig fragment No. 61. |
| GenBank | ATAC002343 | 0.0 | AC002343.1 Arabidopsis thaliana chromosome IV BAC T19F6 genomic sequence, complete sequence. |
| GenBank | CP002687 | 0.0 | CP002687.1 Arabidopsis thaliana chromosome 4 sequence. |
| Publications
? help Back to Top |
- Froehlich JE, et al.
Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.
J. Proteome Res., 2003 Jul-Aug. 2(4): p. 413-25
[PMID:12938931] - Kim JH,Choi D,Kende H
The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis.
Plant J., 2003. 36(1): p. 94-104
[PMID:12974814] - Jones-Rhoades MW,Bartel DP
Computational identification of plant microRNAs and their targets, including a stress-induced miRNA.
Mol. Cell, 2004. 14(6): p. 787-99
[PMID:15200956] - Kim JH,Kende H
A transcriptional coactivator, AtGIF1, is involved in regulating leaf growth and morphology in Arabidopsis.
Proc. Natl. Acad. Sci. U.S.A., 2004. 101(36): p. 13374-9
[PMID:15326298] - Skinner DJ,Gasser CS
Expression-based discovery of candidate ovule development regulators through transcriptional profiling of ovule mutants.
BMC Plant Biol., 2009. 9: p. 29
[PMID:19291320] - Liu D,Song Y,Chen Z,Yu D
Ectopic expression of miR396 suppresses GRF target gene expression and alters leaf growth in Arabidopsis.
Physiol Plant, 2009. 136(2): p. 223-36
[PMID:19453503] - Hanada K, et al.
Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
Mol. Biol. Evol., 2011. 28(1): p. 377-82
[PMID:20736450] - Liang G,He H,Li Y,Wang F,Yu D
Molecular mechanism of microRNA396 mediating pistil development in Arabidopsis.
Plant Physiol., 2014. 164(1): p. 249-58
[PMID:24285851] - Cao Y,Han Y,Jin Q,Lin Y,Cai Y
Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa).
Front Plant Sci, 2016. 7: p. 1750
[PMID:27933074]
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