PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT4G06634.1
Common NameAtYY1, F8H12, YY1
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 387aa    MW: 44703.4 Da    PI: 6.47
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT4G06634.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H210.80.001681103323
                  ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                  C+   Cgk+F + s L++H   H
  AT4G06634.1  81 CSydGCGKTFFDVSALRKHSHIH 103
                  78889**************7766 PP
2zf-C2H2171.7e-05108132123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+C    Cgk F ++s LkrH   H
  AT4G06634.1 108 YVCDqeGCGKKFLDSSKLKRHYLIH 132
                  99*******************9988 PP
3zf-C2H220.11.7e-06138162123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y C+   Cgk Fs   nL++H++tH
  AT4G06634.1 138 YICTyeGCGKAFSLDFNLRSHMKTH 162
                  899999******************9 PP
4zf-C2H212.90.00033230255123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  y Cp   C k + + + Lk H+++ H
  AT4G06634.1 230 YACPyeGCEKAYIHEYKLKLHLKReH 255
                  89*********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.603.7E-1474105IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.94979108IPR007087Zinc finger, C2H2
SMARTSM003550.005379103IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028081103IPR007087Zinc finger, C2H2
SuperFamilySSF576672.69E-982132No hitNo description
Gene3DG3DSA:3.30.160.604.9E-14106130IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015714.274108137IPR007087Zinc finger, C2H2
SMARTSM003550.0011108132IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280110132IPR007087Zinc finger, C2H2
SuperFamilySSF576673.55E-15119175No hitNo description
Gene3DG3DSA:3.30.160.605.9E-21131164IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003555.2E-4138162IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.84138167IPR007087Zinc finger, C2H2
PROSITE patternPS000280140162IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.8E-6165189IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.12168193IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280170193IPR007087Zinc finger, C2H2
SuperFamilySSF576671.33E-5225253No hitNo description
Gene3DG3DSA:3.30.160.606.7E-9226252IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.012230255IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.328230260IPR007087Zinc finger, C2H2
PROSITE patternPS000280232255IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
Sequence ? help Back to Top
Protein Sequence    Length: 387 aa     Download sequence    Send to blast
MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATG GKCHLHKWVT EDTFSRLKEK  60
EKEPDVPEPE PEPTTEILFL CSYDGCGKTF FDVSALRKHS HIHGERQYVC DQEGCGKKFL  120
DSSKLKRHYL IHTGERNYIC TYEGCGKAFS LDFNLRSHMK THSQENYHIC PYSGCVKRYA  180
HEYKLKNHVA AYHEKNGGGE TPKYTPPAEK VLRTVKTPAT VCGPSSDRPY ACPYEGCEKA  240
YIHEYKLKLH LKREHPGHLQ EENADTPTLN KHNGNDRNEI DDGSDQDVYR KHASNGKGQT  300
HKQQSRAKPN MRTPPAKVGK KGSTSSPAKA RIAKKPWQAK ETFEEVEREE EEDSEETEED  360
RDNVEDGWRF GENNEDDDDD EETEYED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C8e-37811928117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.472640.0inflorescence| silique
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT4G06634
AtGenExpressAT4G06634
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Function -- GeneRIF ? help Back to Top
  1. genome-wide target gene analysis revealed that AtYY1 was involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism, and stress response[AtYY1]
    [PMID: 22508367]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT4G06634.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT4G06634
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0731620.0AB073162.1 Arabidopsis thaliana DNA, chromosome 4 centromere region, BAC clone:F8H12.
GenBankCP0026870.0CP002687.1 Arabidopsis thaliana chromosome 4 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_849323.10.0zinc finger (C2H2 type) family protein
SwissprotQ2V3L30.0YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A178V3M90.0A0A178V3M9_ARATH; Uncharacterized protein
STRINGAT4G06634.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58592846
Representative plantOGRP38561626
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Reiland S, et al.
    Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.
    Plant Physiol., 2009. 150(2): p. 889-903
    [PMID:19376835]
  3. Rehrauer H, et al.
    AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling.
    Plant Physiol., 2010. 152(2): p. 487-99
    [PMID:20032078]
  4. Wu X,Cheng Y,Li T,Wang Z,Liu JY
    In vitro identification of DNA-binding motif for the new zinc finger protein AtYY1.
    Acta Biochim. Biophys. Sin. (Shanghai), 2012. 44(6): p. 483-9
    [PMID:22508367]
  5. Lai Z, et al.
    MED18 interaction with distinct transcription factors regulates multiple plant functions.
    Nat Commun, 2014. 5: p. 3064
    [PMID:24451981]
  6. Bieluszewski T, et al.
    AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex.
    BMC Plant Biol., 2015. 15: p. 75
    [PMID:25849764]
  7. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  8. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]