PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 277aa MW: 31572.1 Da PI: 5.1099

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT3G57600.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	64.5	2.2e-20	26	77	1	56
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56 ++y+GVr++ +g+WvAeIr+p++ r+r +lg+f taeeAa a+++a++kl+g+ AT3G57600.1 26 CQYRGVRQRT-WGKWVAEIREPKK---RARLWLGSFATAEEAAMAYDEAALKLYGH 77 68***999.******965...5***********************996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.35E-31	26	86	No hit	No description
Pfam	PF00847	4.0E-14	26	77	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	9.15E-22	27	85	IPR016177	DNA-binding domain
SMART	SM00380	8.4E-37	27	90	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.261	27	84	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.9E-30	27	85	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.2E-10	28	39	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.2E-10	50	66	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009052	anatomy	flower pedicel
PO:0020038	anatomy	petiole
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 277 aa Download sequence Send to blast
MEKSSSMKQW KKGPARGKGG PQNALCQYRG VRQRTWGKWV AEIREPKKRA RLWLGSFATA 60 EEAAMAYDEA ALKLYGHDAY LNLPHLQRNT RPSLSNSQRF KWVPSRKFIS MFPSCGMLNV 120 NAQPSVHIIQ QRLEELKKTG LLSQSYSSSS SSTESKTNTS FLDEKTSKGE TDNMFEGGDQ 180 KKPEIDLTEF LQQLGILKDE NEAEPSEVAE CHSPPPWNEQ EETGSPFRTE NFSWDTLIEM 240 PRSETTTMQF DSSNFGSYDF EDDVSFPSIW DYYGSLD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	3e-18	27	84	2	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	251598_at	0.0
Expression Atlas	AT3G57600	-
AtGenExpress	AT3G57600	-
ATTED-II	AT3G57600	-

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the DREB subfamily A-2 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are eight members in this subfamily including DREB2A AND DREB2B that are involved in response to drought.
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity-inducible transcription. {ECO:0000269\|PubMed:11798174}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00411	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT3G57600.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By high-salt stress. {ECO:0000269\|PubMed:11798174}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT1G14920

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT3G57600

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK227217	0.0	AK227217.1 Arabidopsis thaliana mRNA for AP2 transcription factor - like protein, complete cds, clone: RAFL09-96-P04.
GenBank	AL049660	0.0	AL049660.1 Arabidopsis thaliana DNA chromosome 3, BAC clone F15B8.
GenBank	AY087243	0.0	AY087243.1 Arabidopsis thaliana clone 332 mRNA, complete sequence.
GenBank	BT028945	0.0	BT028945.1 Arabidopsis thaliana At3g57600 mRNA, complete cds.
GenBank	CP002686	0.0	CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_191319.1	0.0	Integrase-type DNA-binding superfamily protein
Swissprot	Q9SVX5	0.0	DRE2F_ARATH; Dehydration-responsive element-binding protein 2F
TrEMBL	A0A178VB25	0.0	A0A178VB25_ARATH; Uncharacterized protein
STRING	AT3G57600.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM8168	26	38
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT3G57600.1
Entrez Gene	824929
iHOP	AT3G57600
wikigenes	AT3G57600

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Sakuma Y, et al. DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression. Biochem. Biophys. Res. Commun., 2002. 290(3): p. 998-1009 [PMID:11798174] Jiao Y, et al. A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development. Plant Physiol., 2003. 133(4): p. 1480-93 [PMID:14605227] Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes. Plant J., 2004. 38(2): p. 366-79 [PMID:15078338] Pineau C, et al. hca: an Arabidopsis mutant exhibiting unusual cambial activity and altered vascular patterning. Plant J., 2005. 44(2): p. 271-89 [PMID:16212606] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Welling A,Palva ET Involvement of CBF transcription factors in winter hardiness in birch. Plant Physiol., 2008. 147(3): p. 1199-211 [PMID:18467468] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Mar Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners. Plant Physiol., 2014. 166(2): p. 1022-32 [PMID:25118255]