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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT3G50870.1 |
| Common Name | F18B3.150, GATA18, HAN, MNP |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
GATA |
| Protein Properties |
Length: 295aa MW: 31831.5 Da PI: 8.0055 |
| Description |
GATA family protein |
| Gene Model |
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| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | GATA | 63.2 | 3e-20 | 154 | 188 | 1 | 35 |
GATA 1 CsnCgttkTplWRrgpdgnktLCnaCGlyyrkkgl 35
C+nC tt+TplWR+gp+g+k+LCnaCG++++k+++
AT3G50870.1 154 CANCDTTSTPLWRNGPRGPKSLCNACGIRFKKEER 188
********************************986 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0009793 | Biological Process | embryo development ending in seed dormancy |
| GO:0009909 | Biological Process | regulation of flower development |
| GO:0030154 | Biological Process | cell differentiation |
| GO:0045944 | Biological Process | positive regulation of transcription from RNA polymerase II promoter |
| GO:0005634 | Cellular Component | nucleus |
| GO:0005667 | Cellular Component | transcription factor complex |
| GO:0000977 | Molecular Function | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0001085 | Molecular Function | RNA polymerase II transcription factor binding |
| GO:0001228 | Molecular Function | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding |
| GO:0003682 | Molecular Function | chromatin binding |
| GO:0008270 | Molecular Function | zinc ion binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 295 aa
Download sequence Send
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MMQTPYTTST QGQYCHSCGM FHHHSQSCCY NNNNNSNAGS YSMVFSMQNG GVFEQNGEDY 60
HHSSSLVDCT LSLGTPSTRL CEEDEKRRRS TSSGASSCIS NFWDLIHTKN NNSKTAPYNN 120
VPSFSANKPS RGCSGGGGGG GGGGGGDSLL ARRCANCDTT STPLWRNGPR GPKSLCNACG 180
IRFKKEERRT TAATGNTVVG AAPVQTDQYG HHNSGYNNYH AATNNNNNNG TPWAHHHSTQ 240
RVPCNYPANE IRFMDDYGSG VANNVESDGA HGGVPFLSWR LNVADRASLV HDFTR
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: In the developing axillary shoot apical meristem (SAM), expressed at the boundary between nascent axillary meristems and the adaxial side of leaves. In all mature SAMs, located at the boundaries between the central SAM and the initiating organ primordia, as well as between the neighboring initiating organ primordia. In the floral meristem, strongly expressed at the boundaries between the meristematic dome and the initiating floral organ primordia, and also at the boundaries between the primordia of different whorls. Expression at the boundaries attenuates as the organ primordia grow apart. In flowers, localized at the boundary between the central meristematic cells and differentiating stamen primordia to later accumulates at the medial ridge region of the carpel. Highly expressed in the developing anthers, in both the tapetum cell layer and microsporocytes. In developing ovules, confined to inner and outer integuments. In aerial tissues, strongly present in phloem tissues (PubMed:15367721). First observed in the whole embryo, but later confined to the center cells of the embryo and provascular tissues (PubMed:15367721, PubMed:20643354). {ECO:0000269|PubMed:15367721, ECO:0000269|PubMed:20643354}. |
| Uniprot | TISSUE SPECIFICITY: Expressed in vegetative and inflorescence shoot apical meristems (SAMs), axillary (SAMs), floral meristems, developing ovules and stamens, vascular tissues, and in the embryo. {ECO:0000269|PubMed:15367721, ECO:0000269|PubMed:26390296}. |
| Functional Description ? help
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| Source |
Description |
| TAIR | Encodes a GATA factort transcriptional regulator required to position the proembryo boundary in the early embryo. |
| UniProt | Transcriptional factor that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (including its own promoter and GATA21 promoter), thus regulating the expression of genes mostly involved in hormone responses and floral organ specification (including genes regulating hormones responses) (PubMed:23335616, PubMed:26390296). Regulates both flower and shoot apical meristem (SAM) development, especially for establishing organ boundaries in shoots and flowers, probably by controlling the number and position of WUS-expressing cells (PubMed:15367721, PubMed:23335616). Coregulates, with AGO10/PNH, the shoot apical meristem (SAM) organization. Regulates floral organ development via the promotion of JAG and NPR5/BOP2 expression. Modulates cytokinin homeostasis in organ boundaries by regulating CKX3 expression (PubMed:26390296). Involved in cell proliferation and differentiation (PubMed:15367721). Required to position the inductive proembryo boundary via the regulation of gene expression and for early embryonic development (PubMed:20643354). Together with GIF1/AN3, mediates cotyledon identity by preventing ectopic root formation through the repression of PLT1 expression (PubMed:22669825). {ECO:0000269|PubMed:15367721, ECO:0000269|PubMed:20643354, ECO:0000269|PubMed:22669825, ECO:0000269|PubMed:23335616, ECO:0000269|PubMed:26390296}. |
| Function -- GeneRIF ? help
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- Mutations in HAN cause a coordinated apical shift of gene expression patterns, revealing that HAN regulates transcription in the basal proembryo. [GATA factor HANABA TARANU]
[PMID: 20643354] - The data suggested that establishing cotyledon identity requires both GIF1 and HANABA TARANU to repress ectopic root formation by repressing PLETHORA1 expression.
[PMID: 22669825] - HAN functions as a key repressor that regulates floral development via regulatory networks involving genes in the GATA3 family, along with genes involved in hormone action and floral organ specification.
[PMID: 23335616] - HAN physically interacts with JAG, and directly stimulates the expression of JAG and BOP2 to regulate floral organ development
[PMID: 26390296]
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| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Repressed via a negative regulatory feedback loop. {ECO:0000269|PubMed:23335616}. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AB493644 | 0.0 | AB493644.1 Arabidopsis thaliana At3g50870 mRNA for hypothetical protein, partial cds, clone: RAAt3g50870. |
| Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Jeong MJ,Jeong MJ,Shih MC
Interaction of a GATA factor with cis-acting elements involved in light regulation of nuclear genes encoding chloroplast glyceraldehyde-3-phosphate dehydrogenase in Arabidopsis.
Biochem. Biophys. Res. Commun., 2003. 300(2): p. 555-62
[PMID:12504119] - Reyes JC,Muro-Pastor MI,Florencio FJ
The GATA family of transcription factors in Arabidopsis and rice.
Plant Physiol., 2004. 134(4): p. 1718-32
[PMID:15084732] - Zhao Y, et al.
HANABA TARANU is a GATA transcription factor that regulates shoot apical meristem and flower development in Arabidopsis.
Plant Cell, 2004. 16(10): p. 2586-600
[PMID:15367721] - Nawy T, et al.
Transcriptional profile of the Arabidopsis root quiescent center.
Plant Cell, 2005. 17(7): p. 1908-25
[PMID:15937229] - Nakayama N, et al.
Gene trap lines define domains of gene regulation in Arabidopsis petals and stamens.
Plant Cell, 2005. 17(9): p. 2486-506
[PMID:16055634] - Bi YM, et al.
Genetic analysis of Arabidopsis GATA transcription factor gene family reveals a nitrate-inducible member important for chlorophyll synthesis and glucose sensitivity.
Plant J., 2005. 44(4): p. 680-92
[PMID:16262716] - Manfield IW,Devlin PF,Jen CH,Westhead DR,Gilmartin PM
Conservation, convergence, and divergence of light-responsive, circadian-regulated, and tissue-specific expression patterns during evolution of the Arabidopsis GATA gene family.
Plant Physiol., 2007. 143(2): p. 941-58
[PMID:17208962] - Stracke R, et al.
Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling.
Plant J., 2007. 50(4): p. 660-77
[PMID:17419845] - Ho LH, et al.
Identification of regulatory pathways controlling gene expression of stress-responsive mitochondrial proteins in Arabidopsis.
Plant Physiol., 2008. 147(4): p. 1858-73
[PMID:18567827] - Whipple CJ, et al.
A conserved mechanism of bract suppression in the grass family.
Plant Cell, 2010. 22(3): p. 565-78
[PMID:20305121] - Nawy T, et al.
The GATA factor HANABA TARANU is required to position the proembryo boundary in the early Arabidopsis embryo.
Dev. Cell, 2010. 19(1): p. 103-13
[PMID:20643354] - Causier B,Ashworth M,Guo W,Davies B
The TOPLESS interactome: a framework for gene repression in Arabidopsis.
Plant Physiol., 2012. 158(1): p. 423-38
[PMID:22065421] - Kanei M,Horiguchi G,Tsukaya H
Stable establishment of cotyledon identity during embryogenesis in Arabidopsis by ANGUSTIFOLIA3 and HANABA TARANU.
Development, 2012. 139(13): p. 2436-46
[PMID:22669825] - Zhang X, et al.
Transcription repressor HANABA TARANU controls flower development by integrating the actions of multiple hormones, floral organ specification genes, and GATA3 family genes in Arabidopsis.
Plant Cell, 2013. 25(1): p. 83-101
[PMID:23335616] - Behringer C,Bastakis E,Ranftl QL,Mayer KF,Schwechheimer C
Functional diversification within the family of B-GATA transcription factors through the leucine-leucine-methionine domain.
Plant Physiol., 2014. 166(1): p. 293-305
[PMID:25077795] - Ding L, et al.
HANABA TARANU (HAN) Bridges Meristem and Organ Primordia Boundaries through PINHEAD, JAGGED, BLADE-ON-PETIOLE2 and CYTOKININ OXIDASE 3 during Flower Development in Arabidopsis.
PLoS Genet., 2015. 11(9): p. e1005479
[PMID:26390296]
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