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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT3G19510.1 |
| Common Name | HAT3.1, MLD14.25, MLD14.37 |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
HB-PHD |
| Protein Properties |
Length: 723aa MW: 80461.5 Da PI: 4.4341 |
| Description |
Homeodomain-like protein with RING/FYVE/PHD-type zinc finger domain |
| Gene Model |
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| Signature Domain? help Back to Top |
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| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | Homeobox | 40.3 | 5.2e-13 | 622 | 666 | 8 | 52 |
-HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHH CS
Homeobox 8 tkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrR 52
t+ +++L F++n+yp+++++e LAk+l++t +qV +WF+ rR
AT3G19510.1 622 TDPKTQRLYISFQENQYPDKATKESLAKELQMTVKQVNNWFKHRR 666
5667899999**********************************9 PP
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| 2 | PHD | 40.5 | 6.4e-14 | 267 | 322 | 1 | 51 |
SBTTTSS..TCTTSSEEEBSS.SSSEEETTTSTSSSSHHSHHSS..TBSSHHHHTT CS
PHD 1 rCkvCgk..sdeegelvlCdg.CkewfHlkClglkleseekpeg..ewlCeeCkek 51
+C+ Cg+ +++++lCdg C++ fH++Cl+++l++e++p + wlC+ C++k
AT3G19510.1 267 FCAKCGSkdLSVDNDIILCDGfCDRGFHQYCLEPPLRKEDIPPDdeGWLCPGCDCK 322
699***955445********88*******************99999*******985 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| GO:0005515 | Molecular Function | protein binding |
| GO:0008270 | Molecular Function | zinc ion binding |
| GO:0043565 | Molecular Function | sequence-specific DNA binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 723 aa
Download sequence Send
to blast |
MYKAVSKRVT RSSGSGLKQT NVDNGGEISP TVDRVSEQGK SSEAGSHMPT DANGNGHLHH 60
EIMDHGKGNE EQKPTPQTVK KDSNTNTKFS GSHRELVIGL PCRGQFEIHN RSRASTSSKR 120
LGGGGERNVL FASHKRAQRS KEDAGPSSVV ANSTPVGRPK KKNKTMNKGQ VREDDEYTRI 180
KKKLRYFLNR INYEQSLIDA YSLEGWKGSS LEKIRPEKEL ERATKEILRR KLKIRDLFQH 240
LDTLCAEGSL PESLFDTDGE ISSEDIFCAK CGSKDLSVDN DIILCDGFCD RGFHQYCLEP 300
PLRKEDIPPD DEGWLCPGCD CKDDSLDLLN DSLGTKFSVS DSWEKIFPEA AAALVGGGQN 360
LDCDLPSDDS DDEEYDPDCL NDNENDEDGS DDNEESENED GSSDETEFTS ASDEMIESFK 420
EGKDIMKDVM ALPSDDSEDD DYDPDAPTCD DDKESSNSDC TSDTEDLETS FKGDETNQQA 480
EDTPLEDPGR QTSQLQGDAI LESDVGLDDG PAGVSRRRNV ERLDYKKLYD EEYDNVPTSS 540
SDDDDWDKTA RMGKEDSESE DEGDTVPLKQ SSNAEDHTSK KLIRKSKRAD KKDTLEMPQE 600
GPGENGGSGE IEKSSSSACK QTDPKTQRLY ISFQENQYPD KATKESLAKE LQMTVKQVNN 660
WFKHRRWSIN SKPLVSEENV EKLKTGKEGE CETSVAGSSK QTMETESVAE KPTNTGSRKR 720
RRK
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| Nucleic Localization
Signal ? help
Back to Top |
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| No. |
Start |
End |
Sequence |
| 1 | 178 | 184 | RIKKKLR |
| 2 | 717 | 721 | RKRRR |
| Expression --
Description ? help
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| Source |
Description |
| Uniprot | TISSUE SPECIFICITY: Primarily detected in root tissue. |
| Functional Description ? help
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| Source |
Description |
| TAIR | Encodes a member of the PHD-finger homeodomain protein family. The HAT3.1 homeodomain is highly divergent in sequence even at positions that are almost invariable among homeodomains. HAT3.1 shows a preference for the sequence T(A/G)(A/C)ACCA, different from those bound by other homeodomains. |
| UniProt | Binds only to large DNA fragments. Recognizes a DNA fragment carrying 8 copies of box7 motif of the light-induced cab-E promoter of Nicotiana plumbaginifolia. Also recognizes the box7m1 motif. |
| Function -- GeneRIF ? help
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- The interaction of HAT3.1 with specific DNA binding by a homeodomain protein with histidine at position 51 was studied.
[PMID: 17530779]
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| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AK117105 | 0.0 | AK117105.1 Arabidopsis thaliana At3g19510 mRNA for putative homeobox protein HAT3.1, complete cds, clone: RAFL16-64-G01. |
| GenBank | BT005965 | 0.0 | BT005965.1 Arabidopsis thaliana At3g19510 gene, complete cds. |
| Publications
? help Back to Top |
- Halbach T,Scheer N,Werr W
Transcriptional activation by the PHD finger is inhibited through an adjacent leucine zipper that binds 14-3-3 proteins.
Nucleic Acids Res., 2000. 28(18): p. 3542-50
[PMID:10982874] - Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Seki M, et al.
Functional annotation of a full-length Arabidopsis cDNA collection.
Science, 2002. 296(5565): p. 141-5
[PMID:11910074] - Yamada K, et al.
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Science, 2003. 302(5646): p. 842-6
[PMID:14593172] - Tan QK,Irish VF
The Arabidopsis zinc finger-homeodomain genes encode proteins with unique biochemical properties that are coordinately expressed during floral development.
Plant Physiol., 2006. 140(3): p. 1095-108
[PMID:16428600] - Viola IL,Gonzalez DH
Interaction of the PHD-finger homeodomain protein HAT3.1 from Arabidopsis thaliana with DNA. Specific DNA binding by a homeodomain with histidine at position 51.
Biochemistry, 2007. 46(25): p. 7416-25
[PMID:17530779] - Shin R,Jez JM,Basra A,Zhang B,Schachtman DP
14-3-3 proteins fine-tune plant nutrient metabolism.
FEBS Lett., 2011. 585(1): p. 143-7
[PMID:21094157] - Arabidopsis Interactome Mapping Consortium
Evidence for network evolution in an Arabidopsis interactome map.
Science, 2011. 333(6042): p. 601-7
[PMID:21798944] - Sanz-Fernández M, et al.
Screening Arabidopsis mutants in genes useful for phytoremediation.
J. Hazard. Mater., 2017. 335: p. 143-151
[PMID:28441590] - Schindler U,Beckmann H,Cashmore AR
HAT3.1, a novel Arabidopsis homeodomain protein containing a conserved cysteine-rich region.
Plant J., 1993. 4(1): p. 137-50
[PMID:8106082]
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