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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
AT3G03200.1 |
Common Name | anac045, NAC045, T17B22.11 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Family |
NAC |
Protein Properties |
Length: 479aa MW: 55587.6 Da PI: 5.3407 |
Description |
NAC domain containing protein 45 |
Gene Model |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | NAM | 176 | 1.1e-54 | 6 | 133 | 1 | 128 |
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskk 96
lppGfrFhPtdeel+++yLk+k++g ++el evi+evd+yk+ePwdLp k + ++++ewyfFs+rd+ky++g+r+nratk gyWkatgkd++v +
AT3G03200.1 6 LPPGFRFHPTDEELITYYLKRKINGLEIEL-EVIAEVDLYKCEPWDLPgKsLLPSKDQEWYFFSPRDRKYPNGSRTNRATKGGYWKATGKDRRVSW-R 101
79****************************.99***************6345667999*************************************9.8 PP
NAM 97 gelvglkktLvfykgrapkgektdWvmheyrl 128
++++g+kktLv+y+grap+g +t Wvmheyrl
AT3G03200.1 102 DRAIGTKKTLVYYRGRAPHGIRTGWVMHEYRL 133
899***************************98 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
GO:0007275 | Biological Process | multicellular organism development |
GO:0090602 | Biological Process | sieve element enucleation |
GO:0005634 | Cellular Component | nucleus |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
GO:0005515 | Molecular Function | protein binding |
GO:0044212 | Molecular Function | transcription regulatory region DNA binding |
Sequence ? help Back to Top |
Protein Sequence Length: 479 aa
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MAPVSLPPGF RFHPTDEELI TYYLKRKING LEIELEVIAE VDLYKCEPWD LPGKSLLPSK 60 DQEWYFFSPR DRKYPNGSRT NRATKGGYWK ATGKDRRVSW RDRAIGTKKT LVYYRGRAPH 120 GIRTGWVMHE YRLDETECEP SAYGMQDAYA LCRVFKKIVI EAKPRDQHRS YVHAMSNVSG 180 NCSSSFDTCS DLEISSTTHQ VQNTFQPRFG NERFNSNAIS NEDWSQYYGS SYRPFPTPYK 240 VNTEIECSML QHNIYLPPLR VENSAFSDSD FFTSMTHNND HGVFDDFTFA ASNSNHNNSV 300 GDQVIHVGNY DEQLITSNRH MNQTGYIKEQ KIRSSLDNTD EDPGFHGNNT NDNIDIDDFL 360 SFDIYNEDNV NQIEDNEDVN TNETLDSSGF EVVEEETRFN NQMLISTYQT TKILYHQVVP 420 CHTLKVHVNP ISHNVEERTL FIEEDKDSWL QRAEKITKTK LTLFSLMAQQ YYKCLAIFF
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3D Structure ? help Back to Top |
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PDB ID |
Evalue |
Query Start |
Query End |
Hit Start |
Hit End |
Description |
1ut4_A | 3e-55 | 1 | 157 | 12 | 165 | NO APICAL MERISTEM PROTEIN |
1ut4_B | 3e-55 | 1 | 157 | 12 | 165 | NO APICAL MERISTEM PROTEIN |
1ut7_A | 3e-55 | 1 | 157 | 12 | 165 | NO APICAL MERISTEM PROTEIN |
1ut7_B | 3e-55 | 1 | 157 | 12 | 165 | NO APICAL MERISTEM PROTEIN |
4dul_A | 3e-55 | 1 | 157 | 12 | 165 | NAC domain-containing protein 19 |
4dul_B | 3e-55 | 1 | 157 | 12 | 165 | NAC domain-containing protein 19 |
Search in ModeBase |
Expression --
Description ? help
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Source |
Description |
Uniprot | TISSUE SPECIFICITY: Expressed in a few sieve element cells before enucleation and in phloem-pole pericycle cells. {ECO:0000269|PubMed:25081480}. |
Functional Description ? help
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Source |
Description |
UniProt | Transcription factor directing sieve element enucleation and cytosol degradation. Not required for formation of lytic vacuoles. Regulates, with NAC086, the transcription of NEN1, NEN2, NEN3, NEN4, RTM1, RTM2, UBP16, PLDZETA, ABCB10 and At1g26450. {ECO:0000269|PubMed:25081480}. |
Function -- GeneRIF ? help
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- NAC45/86 orchestrate the enucleation, perinuclear organelle clustering, shift in NEN1 and NEN2 localization, and cytosol degradation by regulating the expression of a set of target genes, including NEN1, NEN2, and NEN4. [NAC45]
[PMID: 25081480]
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Regulation -- Description ? help
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Source |
Description |
UniProt | INDUCTION: Regulated by the transcription factor APL (AC Q9SAK5). {ECO:0000269|PubMed:25081480}. |
Phenotype -- Disruption Phenotype ? help
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Source |
Description |
UniProt | DISRUPTION PHENOTYPE: No visible phenotype, due to the redundancy with NAC086 (AC Q9FFI5). Nac045 and nac086 double mutants exhibit seedling lethality with defective development of the protophloem sieve element. {ECO:0000269|PubMed:25081480}. |
Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] - Ooka H, et al.
Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis thaliana. DNA Res., 2003. 10(6): p. 239-47 [PMID:15029955] - Duarte JM, et al.
Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] - Brady SM, et al.
A stele-enriched gene regulatory network in the Arabidopsis root. Mol. Syst. Biol., 2011. 7: p. 459 [PMID:21245844] - Furuta KM, et al.
Plant development. Arabidopsis NAC45/86 direct sieve element morphogenesis culminating in enucleation. Science, 2014. 345(6199): p. 933-7 [PMID:25081480]
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