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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT3G01600.1 |
| Common Name | anac044, F4P13.14, NAC044 |
| Organism |
|
| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
NAC |
| Protein Properties |
Length: 370aa MW: 40827.2 Da PI: 5.4979 |
| Description |
NAC domain containing protein 44 |
| Gene Model |
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| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | NAM | 99.6 | 4.5e-31 | 55 | 196 | 1 | 128 |
NAM 1 lppGfrFhPtdeelvveyLkkkvegkk......lelee.....vikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknra.......tks 80
lp+G++F+Ptde+++ e+L++k+ + e v ++v+i++++P++Lp ++++ +++fF+k+ ++y tg+rk+r+ +
AT3G01600.1 55 LPKGVKFEPTDEDII-EFLEAKCGIGGsephvlI---EefirpVTEDVGINYTHPQNLP-GANKDGVSVFFFHKTVQAYGTGQRKRRKitptlvnDEP 147
799************.9*****876664566552...13445467889***********.445566799******************74555554337 PP
NAM 81 gyWkatgkdkevlskkgelvglkktLvfykg..rapkgektdWvmheyrl 128
+W++tg++k+v+ +g + g+kk++v+yk + k+ek++Wv+h+y+l
AT3G01600.1 148 VRWHKTGRTKPVML-SGVQRGCKKIMVLYKSarKGTKPEKSNWVLHQYHL 196
88************.999***********5432566777*********98 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0007275 | Biological Process | multicellular organism development |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 370 aa
Download sequence Send
to blast |
MARAWIVDGR GIAAKVKNAS LSSALQIQDC GAHIKCPNCT YRIDNSNVLI PWPGLPKGVK 60
FEPTDEDIIE FLEAKCGIGG SEPHVLIEEF IRPVTEDVGI NYTHPQNLPG ANKDGVSVFF 120
FHKTVQAYGT GQRKRRKITP TLVNDEPVRW HKTGRTKPVM LSGVQRGCKK IMVLYKSARK 180
GTKPEKSNWV LHQYHLGTEG KEIGDYVVSK ITYQQQKLGE NPDEGESSSG VRGGPTTPKT 240
NTPTPPSLVD GVAGDEEAFD DLKMFDPFFE ELDSIPEAAL GKMWSKKARM DEEFVVNLSE 300
DNLICDESME ASSLWENQVL PNPSLGTVGD FDGFSISDLE NADLGTPPDF LTVRSCLKKT 360
LFTFGKFNGT
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | TISSUE SPECIFICITY: Expressed in shoot and root apical meristems, in lateral root primordia, in the vasculature of young leaves and in the root stele. {ECO:0000269|PubMed:23907539}. |
| Functional Description ? help
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| Source |
Description |
| UniProt | Transcription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress. {ECO:0000269|PubMed:19549833, ECO:0000269|PubMed:20634150, ECO:0000269|PubMed:24399300, ECO:0000305|PubMed:24736489}. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Not induced by zeocin or ionizing radiation treatment. {ECO:0000269|PubMed:23907539}. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | ATAC009325 | 0.0 | AC009325.8 Arabidopsis thaliana chromosome III BAC F4P13 genomic sequence, complete sequence. |
| GenBank | CP002686 | 0.0 | CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence. |
| Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Ooka H, et al.
Comprehensive analysis of NAC family genes in Oryza sativa and Arabidopsis thaliana.
DNA Res., 2003. 10(6): p. 239-47
[PMID:15029955] - Yi D, et al.
The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species.
Plant Cell, 2014. 26(1): p. 296-309
[PMID:24399300] - Biever JJ,Brinkman D,Gardner G
UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation.
J. Exp. Bot., 2014. 65(11): p. 2949-61
[PMID:24591052] - Hu Z,Cools T,Kalhorzadeh P,Heyman J,De Veylder L
Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links.
Plant Cell, 2015. 27(1): p. 149-61
[PMID:25595823] - Chen P,Umeda M
DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana.
Genes Cells, 2015. 20(8): p. 636-46
[PMID:26033196] - Sjogren CA,Bolaris SC,Larsen PB
Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response.
Plant Cell, 2015. 27(9): p. 2501-15
[PMID:26320227] - Yoshiyama KO
SOG1: a master regulator of the DNA damage response in plants.
Genes Genet. Syst., 2016. 90(4): p. 209-16
[PMID:26617076] - Weimer AK, et al.
The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis.
EMBO J., 2016. 35(19): p. 2068-2086
[PMID:27497297] - Davis OM,Ogita N,Inagaki S,Takahashi N,Umeda M
DNA damage inhibits lateral root formation by up-regulating cytokinin biosynthesis genes in Arabidopsis thaliana.
Genes Cells, 2016. 21(11): p. 1195-1208
[PMID:27658920] - Pedroza-García JA, et al.
Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.
Plant Physiol., 2017. 173(3): p. 1735-1749
[PMID:28153919] - Horvath BM, et al.
Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control.
EMBO J., 2017. 36(9): p. 1261-1278
[PMID:28320736] - Sjogren CA,Larsen PB
SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis.
Plant Cell Environ., 2017. 40(9): p. 1849-1860
[PMID:28556304] - Yoshiyama KO,Kaminoyama K,Sakamoto T,Kimura S
Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in Arabidopsis thaliana.
Plant Cell, 2017. 29(12): p. 3255-3268
[PMID:29208704] - Johnson RA, et al.
SUPPRESSOR OF GAMMA RESPONSE1 Links DNA Damage Response to Organ Regeneration.
Plant Physiol., 2018. 176(2): p. 1665-1675
[PMID:29222192] - Ogita N, et al.
Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis.
Plant J., 2018. 94(3): p. 439-453
[PMID:29430765] - Cao X, et al.
Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots.
Chemosphere, 2018. 201: p. 586-594
[PMID:29533809]
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