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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT3G01140.1 |
| Common Name | AtMYB106, MYB106, NOK |
| Organism |
|
| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
MYB |
| Protein Properties |
Length: 388aa MW: 43557.8 Da PI: 8.5555 |
| Description |
myb domain protein 106 |
| Gene Model |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | Myb_DNA-binding | 56.9 | 4.9e-18 | 57 | 104 | 1 | 48 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
+g+WT+eEd++l+ +++++G g+W++ +++ g+ R++k+c++rw +yl
AT3G01140.1 57 KGPWTPEEDQKLLAYIEEHGHGSWRSLPEKAGLQRCGKSCRLRWTNYL 104
79********************************************97 PP
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| 2 | Myb_DNA-binding | 54.3 | 3e-17 | 110 | 155 | 1 | 48 |
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
rg++T +E++ +++++++lG++ W++Ia +++ +Rt++++k++w+++l
AT3G01140.1 110 RGKFTVQEEQTIIQLHALLGNR-WSAIATHLP-KRTDNEIKNYWNTHL 155
89********************.*********.************996 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006357 | Biological Process | regulation of transcription from RNA polymerase II promoter |
| GO:0010091 | Biological Process | trichome branching |
| GO:0005634 | Cellular Component | nucleus |
| GO:0000981 | Molecular Function | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| GO:0001135 | Molecular Function | transcription factor activity, RNA polymerase II transcription factor recruiting |
| GO:0043565 | Molecular Function | sequence-specific DNA binding |
| GO:0044212 | Molecular Function | transcription regulatory region DNA binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 388 aa
Download sequence Send
to blast |
MPIHVRDREK GRLQNLNRDI FCCVSPSIYQ SDAKRAAFVI ILIMIISPCC DKAGLKKGPW 60
TPEEDQKLLA YIEEHGHGSW RSLPEKAGLQ RCGKSCRLRW TNYLRPDIKR GKFTVQEEQT 120
IIQLHALLGN RWSAIATHLP KRTDNEIKNY WNTHLKKRLI KMGIDPVTHK HKNETLSSST 180
GQSKNAATLS HMAQWESARL EAEARLARES KLLHLQHYQN NNNLNKSAAP QQHCFTQKTS 240
TNWTKPNQGN GDQQLESPTS TVTFSENLLM PLGIPTDSSR NRNNNNNESS AMIELAVSSS 300
TSSDVSLVKE HEHDWIRQIN CGSGGIGEGF TSLLIGDSVG RGLPTGKNEA TAGVGNESEY 360
NYYEDNKNYW NSILNLVDSS PSDSATMF
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| Expression --
Description ? help
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| Source |
Description |
| Uniprot | TISSUE SPECIFICITY: Expressed in trichomes, stems, carpels, petals and stamens. {ECO:0000269|PubMed:18805951}. |
| Functional Description ? help
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| Source |
Description |
| TAIR | Encodes a MIXTA-like MYB gene NOECK (NOK). Loss of function mutations show an increased number of branchpoints in leaf trichomes suggesting a role in negative regulation of trichome branching. |
| UniProt | Functions as a repressor of epidermal cell outgrowth and negatively regulate trichome branch formation (PubMed:18805951, PubMed:21070410). Acts as both a positive and negative regulator of cellular outgrowth. Promotes both trichome expansion and branch formation (PubMed:21070410). Coordinately with WIN1/SHN1, participates in the regulation of cuticle biosynthesis and wax accumulation in reproductive organs and trichomes. Functions in cuticle nanoridge formation in petals and stamens, and in morphogenesis of petal conical cells and trichomes (PubMed:23709630). May play a role in the regulation of cuticle formation in vegetative organs (PubMed:24169067). {ECO:0000269|PubMed:18805951, ECO:0000269|PubMed:21070410, ECO:0000269|PubMed:23709630, ECO:0000269|PubMed:24169067}. |
| Function -- GeneRIF ? help
Back to Top |
- combination of transcript profiling and map-based cloning revealed that the NOECK gene of Arabidopsis encodes AtMYB106, a MIXTA-like transcription factor and homolog of cotton GhMYB25
[PMID: 18805951] - roles in both promoting and limiting trichome development
[PMID: 21070410] - Data indicate that the MIXTA-like MYB transcription factors MYB106 and MYB16, which regulate epidermal cell morphology, also regulate cuticle development coordinately with WIN1/SHN1.
[PMID: 23709630]
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| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AF249309 | 0.0 | AF249309.1 Arabidopsis thaliana putative transcription factor (MYB106) mRNA, complete cds. |
| Orthologous Group
? help Back to Top |
| Lineage | Orthologous Group ID | Taxa Number | Gene Number |
| Malvids | OGEM4 | 28 | 2646 |
| Representative plant | OGRP5 | 17 | 1784 |
| Publications
? help Back to Top |
- Luo D,Oppenheimer DG
Genetic control of trichome branch number in Arabidopsis: the roles of the FURCA loci.
Development, 1999. 126(24): p. 5547-57
[PMID:10572032] - Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Stracke R,Werber M,Weisshaar B
The R2R3-MYB gene family in Arabidopsis thaliana.
Curr. Opin. Plant Biol., 2001. 4(5): p. 447-56
[PMID:11597504] - Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
Plant J., 2004. 38(2): p. 366-79
[PMID:15078338] - Yanhui C, et al.
The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.
Plant Mol. Biol., 2006. 60(1): p. 107-24
[PMID:16463103] - Cao D,Cheng H,Wu W,Soo HM,Peng J
Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis.
Plant Physiol., 2006. 142(2): p. 509-25
[PMID:16920880] - Baumann K, et al.
Control of cell and petal morphogenesis by R2R3 MYB transcription factors.
Development, 2007. 134(9): p. 1691-701
[PMID:17376813] - Servet C, et al.
Characterization of a phosphatase 2C protein as an interacting partner of the histone acetyltransferase GCN5 in Arabidopsis.
Biochim. Biophys. Acta, 2008 Jun-Jul. 1779(6-7): p. 376-82
[PMID:18498779] - Jakoby MJ, et al.
Transcriptional profiling of mature Arabidopsis trichomes reveals that NOECK encodes the MIXTA-like transcriptional regulator MYB106.
Plant Physiol., 2008. 148(3): p. 1583-602
[PMID:18805951] - Marks MD,Wenger JP,Gilding E,Jilk R,Dixon RA
Transcriptome analysis of Arabidopsis wild-type and gl3-sst sim trichomes identifies four additional genes required for trichome development.
Mol Plant, 2009. 2(4): p. 803-22
[PMID:19626137] - Plett JM,Mathur J,Regan S
Ethylene receptor ETR2 controls trichome branching by regulating microtubule assembly in Arabidopsis thaliana.
J. Exp. Bot., 2009. 60(13): p. 3923-33
[PMID:19648171] - Plett JM,Wilkins O,Campbell MM,Ralph SG,Regan S
Endogenous overexpression of Populus MYB186 increases trichome density, improves insect pest resistance, and impacts plant growth.
Plant J., 2010. 64(3): p. 419-32
[PMID:20807210] - Gilding EK,Marks MD
Analysis of purified glabra3-shapeshifter trichomes reveals a role for NOECK in regulating early trichome morphogenic events.
Plant J., 2010. 64(2): p. 304-17
[PMID:21070410] - Oshima Y, et al.
MIXTA-like transcription factors and WAX INDUCER1/SHINE1 coordinately regulate cuticle development in Arabidopsis and Torenia fournieri.
Plant Cell, 2013. 25(5): p. 1609-24
[PMID:23709630] - Jin J, et al.
An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
Mol. Biol. Evol., 2015. 32(7): p. 1767-73
[PMID:25750178] - Folkers U,Berger J,H
Cell morphogenesis of trichomes in Arabidopsis: differential control of primary and secondary branching by branch initiation regulators and cell growth.
Development, 1997. 124(19): p. 3779-86
[PMID:9367433]
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