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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT2G47210.1 |
| Common Name | SWC4, T8I13.5 |
| Organism |
|
| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
MYB_related |
| Protein Properties |
Length: 441aa MW: 49823.6 Da PI: 9.7385 |
| Description |
MYB_related family protein |
| Gene Model |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | Myb_DNA-binding | 22.3 | 3.2e-07 | 129 | 171 | 3 | 46 |
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
WT+eE ++l + ++ + + + Ia +++ Rt +++k+r+++
AT2G47210.1 129 VWTKEETDQLFEFCQNFDLR-FVVIADRFPVSRTVEELKDRYYS 171
6*******************.*********************97 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0043967 | Biological Process | histone H4 acetylation |
| GO:0043968 | Biological Process | histone H2A acetylation |
| GO:0045892 | Biological Process | negative regulation of transcription, DNA-templated |
| GO:0000812 | Cellular Component | Swr1 complex |
| GO:0035267 | Cellular Component | NuA4 histone acetyltransferase complex |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| GO:0003714 | Molecular Function | transcription corepressor activity |
| GO:0005515 | Molecular Function | protein binding |
| Sequence ? help Back to Top |
| Protein Sequence Length: 441 aa
Download sequence Send
to blast |
MGGTDAKDIL GLPKTPLSLT QEKKSRPQKE SHRKPDGISR EVYALTGGVA PLMPSIDLKR 60
RPPADEKVAW KWLSFTNSAR KDDLQLYHWV RVVNDVPPTG DYSFAKYNKS VDILKYTDEE 120
YENHLTDSVW TKEETDQLFE FCQNFDLRFV VIADRFPVSR TVEELKDRYY SVNRALLRAR 180
AQSPADVANH PLMKEPYDIT RDRERKRALS MVLSQSRHQE KKDAEILAEA KRITEMRLAA 240
RRAEEPDVSA NENAGLDKAD GVVPGRSVSP TSNSQLPATA VAPSTLTMAD YASTLASLRM 300
LHVYLRTYGL EQMVQAASSA VGLRTIKRVE QTLQDLGVNL KPKVPTKTVC DEHLELRKEI 360
LTLLNLQKQL QYKESEGSSH REGSYAAMPD TPKDRVFAPD PFSFGAERPI KKEQKRKGPG 420
RQADTPSPAH KRPRKLKASD L
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| 3D Structure ? help Back to Top |
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| PDB ID |
Evalue |
Query Start |
Query End |
Hit Start |
Hit End |
Description |
| 3hm5_A | 1e-18 | 101 | 181 | 4 | 88 | DNA methyltransferase 1-associated protein 1 |
| 4iej_A | 1e-18 | 101 | 181 | 4 | 88 | DNA methyltransferase 1-associated protein 1 |
| Search in ModeBase |
| Functional Description ? help
Back to Top |
| Source |
Description |
| UniProt | Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. {ECO:0000305|Ref.5}. |
| Function -- GeneRIF ? help
Back to Top |
- data suggests that SWC4 regulates plant growth and development by aiding SWR1-C recruitment and modulating H2A.Z deposition. [SWC4]
[PMID: 29604400]
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| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | AY064024 | 0.0 | AY064024.1 Arabidopsis thaliana unknown protein (At2g47210) mRNA, complete cds. |
| GenBank | AY096610 | 0.0 | AY096610.1 Arabidopsis thaliana unknown protein (At2g47210) mRNA, complete cds. |
| Publications
? help Back to Top |
- Boisson B,Giglione C,Meinnel T
Unexpected protein families including cell defense components feature in the N-myristoylome of a higher eukaryote.
J. Biol. Chem., 2003. 278(44): p. 43418-29
[PMID:12912986] - Yamada K, et al.
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Science, 2003. 302(5646): p. 842-6
[PMID:14593172] - Arabidopsis Interactome Mapping Consortium
Evidence for network evolution in an Arabidopsis interactome map.
Science, 2011. 333(6042): p. 601-7
[PMID:21798944] - Bieluszewski T, et al.
AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex.
BMC Plant Biol., 2015. 15: p. 75
[PMID:25849764] - Gómez-Zambrano Á, et al.
Arabidopsis SWC4 Binds DNA and Recruits the SWR1 Complex to Modulate Histone H2A.Z Deposition at Key Regulatory Genes.
Mol Plant, 2018. 11(6): p. 815-832
[PMID:29604400]
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