PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 254aa MW: 28414.8 Da PI: 6.5157

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G40200.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	39	1.4e-12	65	111	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r+h +E+rRRdriNs + Lr+l+P++ Kl+Ka+ L ++e +k+L AT2G40200.1 65 RSHRLAEKRRRDRINSHLTALRKLVPNS-----DKLDKAALLATVIEQVKEL 111 68***********************8.....7***********99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	1.09E-13	61	117	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.231	62	111	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.2E-10	65	111	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.8E-14	65	116	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.65E-12	65	114	No hit	No description
SMART	SM00353	2.1E-11	68	117	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd04873	9.82E-4	147	221	No hit	No description
Gene3D	G3DSA:3.30.70.260	1.4E-4	153	217	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0001081	developmental stage	mature plant embryo stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 254 aa Download sequence Send to blast
MENSYDSSKW SDSTTPYMVS WSLQSESSDS DWNRFNLGFS SSSFGGNFPA DDCVGGIEKA 60 ESLSRSHRLA EKRRRDRINS HLTALRKLVP NSDKLDKAAL LATVIEQVKE LKQKAAESPI 120 FQDLPTEADE VTVQPETISD FESNTNTIIF KASFCCEDQP EAISEIIRVL TKLQLETIQA 180 EIISVGGRMR INFILKDSNC NETTNIAASA KALKQSLCSA LNRITSSSTT TSSVCRIRSK 240 RQRWFLSSHY SHNE

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	263380_at	0.0
Expression Atlas	AT2G40200	-
AtGenExpress	AT2G40200	-
ATTED-II	AT2G40200	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed constitutively in roots, stems, and flowers. {ECO:0000269\|PubMed:12679534}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G40200.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by salicylic acid (SA) treatment. {ECO:0000269\|PubMed:12679534}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G40200

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488586	0.0	AF488586.1 Arabidopsis thaliana clone bHLH051 putative bHLH transcription factor mRNA, complete cds.
GenBank	BT029997	0.0	BT029997.1 Arabidopsis thaliana At2g40200 mRNA, complete cds.
GenBank	BT030051	0.0	BT030051.1 Arabidopsis thaliana At2g40200 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_181549.1	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	Q9XEF0	0.0	BH051_ARATH; Transcription factor bHLH51
TrEMBL	A0A384L9H1	0.0	A0A384L9H1_ARATH; Uncharacterized protein
TrEMBL	C0SV80	0.0	C0SV80_ARATH; Uncharacterized protein At2g40200 (Fragment)
STRING	AT2G40200.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6806	25	42
Representative plant	OGRP377	15	106

Link Out ? help Back to Top
Phytozome	AT2G40200.1
Entrez Gene	818611
iHOP	AT2G40200
wikigenes	AT2G40200

Publications ? help Back to Top
Wang ML, et al. A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07. Genome Res., 1999. 9(4): p. 325-33 [PMID:10207155] Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Che P,Lall S,Nettleton D,Howell SH Gene expression programs during shoot, root, and callus development in Arabidopsis tissue culture. Plant Physiol., 2006. 141(2): p. 620-37 [PMID:16648215] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281]