PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

C2H2

Protein Properties

Length: 286aa MW: 31046.6 Da PI: 7.8129

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G28200.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.5	0.00045	115	137	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+C+ C+++Fs+ L H +H AT2G28200.1 115 YECKTCNRTFSSFQALGGHRASH 137 99**********99999998887 PP
2	zf-C2H2	13.3	0.00024	190	212	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++Cg F++ L H+r+H AT2G28200.1 190 HECSICGSEFTSGQALGGHMRRH 212 78********************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	7.51E-9	114	137	No hit	No description
Pfam	PF13912	1.0E-12	114	139	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	10.99	115	142	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.063	115	137	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	117	137	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	7.51E-9	185	212	No hit	No description
Gene3D	G3DSA:3.30.160.60	9.9E-4	188	212	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF13912	1.5E-11	189	213	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.019	190	212	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	9.743	190	212	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	192	212	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0008270	Molecular Function	zinc ion binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009009	anatomy	plant embryo
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 286 aa Download sequence Send to blast
MMMGQDEVGS DQTQIIKGKR TKRQRSSSTF VVTAATTVTS TSSSAGGSGG ERAVSDEYNS 60 AVSSPVTTDC TQEEEDMAIC LIMLARGTVL PSPDLKNSRK IHQKISSENS SFYVYECKTC 120 NRTFSSFQAL GGHRASHKKP RTSTEEKTRL PLTQPKSSAS EEGQNSHFKV SGSALASQAS 180 NIINKANKVH ECSICGSEFT SGQALGGHMR RHRTAVTTIS PVAATAEVSR NSTEEEIEIN 240 IGRSMEQQRK YLPLDLNLPA PEDDLRESKF QGIVFSATPA LIDCHY

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.39	0.0	root

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	265573_at	0.0
Expression Atlas	AT2G28200	-
AtGenExpress	AT2G28200	-
ATTED-II	AT2G28200	-

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in flowers and siliques. {ECO:0000269\|PubMed:9132053}.

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor that may be involved in stress responses. {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G28200.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By gibberellin and H(2)O(2). Down-regulated by ascorbate. {ECO:0000269\|PubMed:12837949, ECO:0000269\|PubMed:16244149}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G28200

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC005851	0.0	AC005851.3 Arabidopsis thaliana chromosome 2 clone F24D13 map B68, complete sequence.
GenBank	AC006202	0.0	AC006202.4 Arabidopsis thaliana chromosome 2 clone T3B23 map mi54, complete sequence.
GenBank	AK175493	0.0	AK175493.1 Arabidopsis thaliana mRNA for putative zinc-finger protein, complete cds, clone: RAFL21-92-D09.
GenBank	AK229812	0.0	AK229812.1 Arabidopsis thaliana mRNA for putative zinc-finger protein, complete cds, clone: RAFL21-88-O10.
GenBank	CP002685	0.0	CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_180387.2	0.0	C2H2-type zinc finger family protein
Swissprot	Q681X4	0.0	ZAT5_ARATH; Zinc finger protein ZAT5
TrEMBL	A0A178VUQ3	0.0	A0A178VUQ3_ARATH; Uncharacterized protein
STRING	AT2G28200.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5862	27	48
Representative plant	OGRP2350	10	35

Link Out ? help Back to Top
Phytozome	AT2G28200.1
Entrez Gene	817366
iHOP	AT2G28200
wikigenes	AT2G28200

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Seki M, et al. Functional annotation of a full-length Arabidopsis cDNA collection. Science, 2002. 296(5565): p. 141-5 [PMID:11910074] Ogawa M, et al. Gibberellin biosynthesis and response during Arabidopsis seed germination. Plant Cell, 2003. 15(7): p. 1591-604 [PMID:12837949] Dal Bosco C, et al. Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. J. Biol. Chem., 2004. 279(2): p. 1060-9 [PMID:14576160] Englbrecht CC,Schoof H,B Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome. BMC Genomics, 2004. 5(1): p. 39 [PMID:15236668] Ramonell K, et al. Loss-of-function mutations in chitin responsive genes show increased susceptibility to the powdery mildew pathogen Erysiphe cichoracearum. Plant Physiol., 2005. 138(2): p. 1027-36 [PMID:15923325] Pavet V, et al. Ascorbic acid deficiency activates cell death and disease resistance responses in Arabidopsis. Plant Physiol., 2005. 139(3): p. 1291-303 [PMID:16244149] Truman W,de Zabala MT,Grant M Type III effectors orchestrate a complex interplay between transcriptional networks to modify basal defence responses during pathogenesis and resistance. Plant J., 2006. 46(1): p. 14-33 [PMID:16553893] Cao D,Cheng H,Wu W,Soo HM,Peng J Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis. Plant Physiol., 2006. 142(2): p. 509-25 [PMID:16920880] Mittler R, et al. Gain- and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress. FEBS Lett., 2006. 580(28-29): p. 6537-42 [PMID:17112521] Huang D,Wu W,Abrams SR,Cutler AJ The relationship of drought-related gene expression in Arabidopsis thaliana to hormonal and environmental factors. J. Exp. Bot., 2008. 59(11): p. 2991-3007 [PMID:18552355] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Meissner R,Michael AJ Isolation and characterisation of a diverse family of Arabidopsis two and three-fingered C2H2 zinc finger protein genes and cDNAs. Plant Mol. Biol., 1997. 33(4): p. 615-24 [PMID:9132053]