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Plant Transcription
Factor Database
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Transcription Factor Information
Basic
Information? help
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TF ID |
AT2G24840.1 |
Common Name | AGL61, DIA, F27C12.24 |
Organism |
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Taxonomic ID |
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Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Family |
M-type_MADS |
Protein Properties |
Length: 264aa MW: 30264.3 Da PI: 10.1557 |
Description |
AGAMOUS-like 61 |
Gene Model |
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Signature Domain? help Back to Top |
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No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
1 | SRF-TF | 67.4 | 1.4e-21 | 72 | 114 | 3 | 45 |
--SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSE CS
SRF-TF 3 ienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgk 45
i+ +s rqvtfskRr+g++KKA+EL++LC+ae+ +i+fs+ k
AT2G24840.1 72 IKKESHRQVTFSKRRAGLFKKASELCTLCGAEIGIIVFSPAKK 114
8999***********************************9876 PP
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Gene Ontology ? help Back to Top |
GO Term |
GO Category |
GO Description |
GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
GO:0009559 | Biological Process | embryo sac central cell differentiation |
GO:0043078 | Cellular Component | polar nucleus |
GO:0003677 | Molecular Function | DNA binding |
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
GO:0005515 | Molecular Function | protein binding |
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
Protein Sequence Length: 264 aa
Download sequence Send
to blast |
MYVTKYKNKL PTLQVDLIIM PHQTQACIYK QTLSLHQIFQ QRKATKTLHT KKTMMSKKKE 60 SIGRQKIPMV KIKKESHRQV TFSKRRAGLF KKASELCTLC GAEIGIIVFS PAKKPFSFGH 120 PSVESVLDRY VSRNNMSLAQ SQQLQGSPAA SCELNMQLTH ILSEVEEEKK KGQAMEEMRK 180 ESVRRSMINW WEKPVEEMNM VQLQEMKYAL EELRKTVVTN MASFNEAKDD VFGFLDNKVT 240 VPPYVNMPSG PSNIYNFANG NGCF
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3D Structure ? help Back to Top |
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PDB ID |
Evalue |
Query Start |
Query End |
Hit Start |
Hit End |
Description |
3kov_A | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3kov_B | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3kov_I | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3kov_J | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3p57_A | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3p57_B | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3p57_C | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3p57_D | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3p57_I | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
3p57_J | 5e-15 | 63 | 134 | 1 | 72 | Myocyte-specific enhancer factor 2A |
5f28_A | 5e-15 | 62 | 134 | 1 | 73 | MEF2C |
5f28_B | 5e-15 | 62 | 134 | 1 | 73 | MEF2C |
5f28_C | 5e-15 | 62 | 134 | 1 | 73 | MEF2C |
5f28_D | 5e-15 | 62 | 134 | 1 | 73 | MEF2C |
Search in ModeBase |
Expression --
Description ? help
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Source |
Description |
Uniprot | DEVELOPMENTAL STAGE: Expressed in the final stages of embryo sac development. {ECO:0000269|PubMed:18713950}. |
Uniprot | TISSUE SPECIFICITY: Expressed exclusively in the central cell of the female gametophyte and in early endosperm. {ECO:0000269|PubMed:18599653, ECO:0000269|PubMed:18713950}. |
Functional Description ? help
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Source |
Description |
TAIR | Encodes a member of the Agamous-like family of transcription factors. Localized to the nucleus in the central cell and endosperm of the female gametophyte. Loss of function mutations show reduced female fertility. Fifty percent of ovules have defective central cells with abnormal morphology and patterns of gene expression. Upon fertilization 50% of seeds abort. Using yeast two hybrid assays AGL61 was shown to interact with AGL80, another MADS box gene with similar defects in ovule development. These data suggest that AGL61 and 80 together are required for proper differentiation of the central cell. |
UniProt | Probable transcription factor. Controls central cell differentiation during female gametophyte development. {ECO:0000269|PubMed:18599653, ECO:0000269|PubMed:18713950}. |
Function -- GeneRIF ? help
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- controls the expression of downstream genes during central cell development
[PMID: 18599653] - DIANA (AGL61) forms a complex with AGL80 to specify the central cell in Arabidopsis ovules. [AGL61] [DIANA]
[PMID: 18713950] - Data show that AGL61 and AGL80 appear to function together to differentiate the central cell in Arabidopsis. Data renamed AGL61 DIANA, after the virginal Roman goddess of the hunt.
[PMID: 18713950]
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Annotation --
Nucleotide ? help
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Source |
Hit ID |
E-value |
Description |
GenBank | AC006585 | 0.0 | AC006585.8 Arabidopsis thaliana chromosome 2 clone F27C12 map mi238, complete sequence. |
GenBank | CP002685 | 0.0 | CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence. |
GenBank | DQ056542 | 0.0 | DQ056542.1 Arabidopsis thaliana MADS-box family protein (At2g24840) mRNA, complete cds. |
Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] - De Bodt S, et al.
Genomewide structural annotation and evolutionary analysis of the type I MADS-box genes in plants. J. Mol. Evol., 2003. 56(5): p. 573-86 [PMID:12698294] - Parenicová L, et al.
Molecular and phylogenetic analyses of the complete MADS-box transcription factor family in Arabidopsis: new openings to the MADS world. Plant Cell, 2003. 15(7): p. 1538-51 [PMID:12837945] - Kofuji R, et al.
Evolution and divergence of the MADS-box gene family based on genome-wide expression analyses. Mol. Biol. Evol., 2003. 20(12): p. 1963-77 [PMID:12949148] - de Folter S, et al.
Comprehensive interaction map of the Arabidopsis MADS Box transcription factors. Plant Cell, 2005. 17(5): p. 1424-33 [PMID:15805477] - Popescu SC, et al.
Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Proc. Natl. Acad. Sci. U.S.A., 2007. 104(11): p. 4730-5 [PMID:17360592] - Johnston AJ, et al.
Genetic subtraction profiling identifies genes essential for Arabidopsis reproduction and reveals interaction between the female gametophyte and the maternal sporophyte. Genome Biol., 2007. 8(10): p. R204 [PMID:17915010] - Steffen JG,Kang IH,Portereiko MF,Lloyd A,Drews GN
AGL61 interacts with AGL80 and is required for central cell development in Arabidopsis. Plant Physiol., 2008. 148(1): p. 259-68 [PMID:18599653] - Bemer M,Wolters-Arts M,Grossniklaus U,Angenent GC
The MADS domain protein DIANA acts together with AGAMOUS-LIKE80 to specify the central cell in Arabidopsis ovules. Plant Cell, 2008. 20(8): p. 2088-101 [PMID:18713950] - Bemer M,Heijmans K,Airoldi C,Davies B,Angenent GC
An atlas of type I MADS box gene expression during female gametophyte and seed development in Arabidopsis. Plant Physiol., 2010. 154(1): p. 287-300 [PMID:20631316] - Zhang S, et al.
FERTILIZATION-INDEPENDENT SEED-Polycomb Repressive Complex 2 Plays a Dual Role in Regulating Type I MADS-Box Genes in Early Endosperm Development. Plant Physiol., 2018. 177(1): p. 285-299 [PMID:29523711]
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