PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G68810.1
Common NameBHLH30, EN53, F14K14.8, T6L1.1
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 368aa    MW: 40825.3 Da    PI: 5.4131
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G68810.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH43.65.2e-14176222354
                  HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                  ++h+e+ErrRR+riN+ +++Lr++lP+      +K +Ka+ L ++++++k+L
  AT1G68810.1 176 KSHSEAERRRRERINNHLAKLRSILPNT-----TKTDKASLLAEVIQHVKEL 222
                  79*************************9.....8****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088816.85173222IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.1E-11176222IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.0E-14177232IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.7E-14177231IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.3E-12179228IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000836.39E-5186225No hitNo description
Gene3DG3DSA:3.30.70.2602.7E-4262317No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 368 aa     Download sequence    Send to blast
MCAKKEEEEE EEEDSSEAMN NIQNYQNDLF FHQLISHHHH HHHDPSQSET LGASGNVGSG  60
FTIFSQDSVS PIWSLPPPTS IQPPFDQFPP PSSSPASFYG SFFNRSRAHH QGLQFGYEGF  120
GGATSAAHHH HEQLRILSEA LGPVVQAGSG PFGLQAELGK MTAQEIMDAK ALAASKSHSE  180
AERRRRERIN NHLAKLRSIL PNTTKTDKAS LLAEVIQHVK ELKRETSVIS ETNLVPTESD  240
ELTVAFTEEE ETGDGRFVIK ASLCCEDRSD LLPDMIKTLK AMRLKTLKAE ITTVGGRVKN  300
VLFVTGEESS GEEVEEEYCI GTIEEALKAV MEKSNVEESS SSGNAKRQRM SSHNTITIVE  360
QQQQYNQR
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1181186ERRRRE
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.468790.0bud| flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453372980.0
Genevisible260034_at0.0
Expression AtlasAT1G68810-
AtGenExpressAT1G68810-
ATTED-IIAT1G68810-
Function -- GeneRIF ? help Back to Top
  1. enhanced expressions of two transcription factors, bHLH30 and MYB101, are able to alter leaf lamina development.
    [PMID: 25268707]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G68810.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G68810
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0721610.0AY072161.1 Arabidopsis thaliana putative DNA-binding protein (At1g68810) mRNA, complete cds.
GenBankAY1229830.0AY122983.1 Arabidopsis thaliana putative DNA-binding protein (At1g68810) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_564944.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9S7Y10.0BH030_ARATH; Transcription factor bHLH30
TrEMBLA0A178WJE60.0A0A178WJE6_ARATH; Uncharacterized protein
STRINGAT1G68810.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM70482843
Representative plantOGRP37715106
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Che P,Lall S,Nettleton D,Howell SH
    Gene expression programs during shoot, root, and callus development in Arabidopsis tissue culture.
    Plant Physiol., 2006. 141(2): p. 620-37
    [PMID:16648215]
  7. Ohashi-Ito K,Bergmann DC
    Regulation of the Arabidopsis root vascular initial population by LONESOME HIGHWAY.
    Development, 2007. 134(16): p. 2959-68
    [PMID:17626058]
  8. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  9. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  10. Ohashi-Ito K, et al.
    A bHLH complex activates vascular cell division via cytokinin action in root apical meristem.
    Curr. Biol., 2014. 24(17): p. 2053-8
    [PMID:25131670]
  11. An R, et al.
    The over-expression of two transcription factors, ABS5/bHLH30 and ABS7/MYB101, leads to upwardly curly leaves.
    PLoS ONE, 2014. 9(9): p. e107637
    [PMID:25268707]
  12. Waidmann S,Kusenda B,Mayerhofer J,Mechtler K,Jonak C
    A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis.
    Plant Cell, 2014. 26(11): p. 4328-44
    [PMID:25387881]
  13. Katayama H, et al.
    A Negative Feedback Loop Controlling bHLH Complexes Is Involved in Vascular Cell Division and Differentiation in the Root Apical Meristem.
    Curr. Biol., 2015. 25(23): p. 3144-50
    [PMID:26616019]