PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G67310.1
Common NameCMTA4, F1N21.13, SR5
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family CAMTA
Protein Properties Length: 1016aa    MW: 113064 Da    PI: 5.1707
Description Calmodulin-binding transcription activator protein with CG-1 and Ankyrin domains
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G67310.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1CG-1168.11.4e-52421582117
         CG-1   2 lke.kkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqrrc 98 
                  ++e ++rwlk+ e++ iL+n+e+ +lt+++++rp+sgsl+L+n++++++frkDG++w++k+dg+++ E+he+LKvg+ e+l+cyYah+e++ptf+rr+
  AT1G67310.1  42 YQEaHSRWLKPPEVLFILQNHESLTLTNTAPQRPTSGSLLLFNKRVLKFFRKDGHQWRRKRDGRAIAEAHERLKVGNAEALNCYYAHGEQDPTFRRRI 139
                  566699******************************************************************************************** PP

         CG-1  99 ywlLeeelekivlvhylev 117
                  yw+L+ e+e+ivlvhy++v
  AT1G67310.1 140 YWMLDPEYEHIVLVHYRDV 158
                  *****************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5143776.14438164IPR005559CG-1 DNA-binding domain
SMARTSM010762.4E-8241159IPR005559CG-1 DNA-binding domain
PfamPF038595.6E-4644158IPR005559CG-1 DNA-binding domain
SuperFamilySSF812964.48E-17447531IPR014756Immunoglobulin E-set
Gene3DG3DSA:2.60.40.104.1E-8447534IPR013783Immunoglobulin-like fold
PfamPF018332.2E-8447530IPR002909IPT domain
CDDcd001022.11E-5447532No hitNo description
Gene3DG3DSA:1.25.40.201.4E-14646741IPR020683Ankyrin repeat-containing domain
SuperFamilySSF484032.8E-15647741IPR020683Ankyrin repeat-containing domain
PROSITE profilePS5029715.326647739IPR020683Ankyrin repeat-containing domain
CDDcd002046.36E-13652739No hitNo description
PfamPF127962.1E-7668740IPR020683Ankyrin repeat-containing domain
SMARTSM002480.011680709IPR002110Ankyrin repeat
PROSITE profilePS5008810.446680712IPR002110Ankyrin repeat
SMARTSM002481900719748IPR002110Ankyrin repeat
SuperFamilySSF525402.6E-11797908IPR027417P-loop containing nucleoside triphosphate hydrolase
SMARTSM0001559797819IPR000048IQ motif, EF-hand binding site
PROSITE profilePS500967.876798826IPR000048IQ motif, EF-hand binding site
SMARTSM000151854876IPR000048IQ motif, EF-hand binding site
PROSITE profilePS500968.187855884IPR000048IQ motif, EF-hand binding site
PfamPF006120.0084857875IPR000048IQ motif, EF-hand binding site
SMARTSM000156.1E-5877899IPR000048IQ motif, EF-hand binding site
PROSITE profilePS500969.267878906IPR000048IQ motif, EF-hand binding site
PfamPF006122.5E-4880899IPR000048IQ motif, EF-hand binding site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0005634Cellular Componentnucleus
GO:0005829Cellular Componentcytosol
GO:0001077Molecular Functiontranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0005516Molecular Functioncalmodulin binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000005anatomycultured plant cell
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 1016 aa     Download sequence    Send to blast
MSSVAEDNSF TCDIATIFVA ICRNPPANPS DSLFQYEIST LYQEAHSRWL KPPEVLFILQ  60
NHESLTLTNT APQRPTSGSL LLFNKRVLKF FRKDGHQWRR KRDGRAIAEA HERLKVGNAE  120
ALNCYYAHGE QDPTFRRRIY WMLDPEYEHI VLVHYRDVSE REEGQQTGGQ VYQFAPILST  180
QNVSYNQYIG DSSDIYQQSS TSPGVAEVNS NLEGSASSSE FGQALKMLKE QLSIGDEHVN  240
SVDPHYIQPE SLDSLQFLEY SDIDHLAQPT TVYQRPENNK LERCYGGNFG AQYSAKNDSN  300
KLERCYGGYV GGAEYHSSNL MLVKNGSGPS GGTGGSGDQG SESWKDVLEA CEASIPLNSE  360
GSTPSSAKGL LAGLQEDSNW SYSNQVDQST FLLPQDLGSF QLPASYSALV APENNGEYCG  420
MMEDGMKIGL PFEQEMRVTG AHNQKFTIQD ISPDWGYANE TTKVIIIGSF LCDPTESTWS  480
CMFGNAQVPF EIIKEGVIRC EAPQCGPGKV NLCITSGDGL LCSEIREFEY REKPDTCCPK  540
CSEPQTSDMS TSPNELILLV RFVQTLLSDR SSERKSNLES GNDKLLTKLK ADDDQWRHVI  600
GTIIDGSASS TSTVDWLLQE LLKDKLDTWL SSRSCDEDYI TCSLSKQEQG IIHMVAGLGF  660
EWAFYPILAH GVNVDFRDIK GWSALHWAAQ FGSEKMVAAL IASGASAGAV TDPSRQDPNG  720
KTAASIAASN GHKGLAGYLS EVALTNHLSS LTLEETENSK DTAQVQTEKT LNSISEQSPS  780
GNEDQVSLKD TLAAVRNAAQ AAARIQAAFR AHSFRKRKQR EAALVACLQE YGMYCEDIEG  840
ISAMSKLTFG KGRNYNSAAL SIQKNFRGYK DRKCFLELRQ KVVKIQAHVR GYQIRKNYKV  900
ICWAVRILDK VVLRWRRKGV GLRGFRQDVE STEDSEDEDI LKVFRKQKVD VAVNEAFSRV  960
LSMSNSPEAR QQYHRVLKRY CQTKAELGKT ETLVGEDDDG LFDIADMEYD TLFSLP
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.493160.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO793741770.0
Genevisible264999_at0.0
Expression AtlasAT1G67310-
AtGenExpressAT1G67310-
ATTED-IIAT1G67310-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. {ECO:0000269|PubMed:12218065}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3' (By similarity). Regulates transcriptional activity in response to calcium signals (Probable). Binds calmodulin in a calcium-dependent manner (By similarity). Involved together with CAMTA2 and CAMTA3 in the positive regulation of a general stress response (PubMed:25039701). {ECO:0000250|UniProtKB:Q8GSA7, ECO:0000269|PubMed:25039701, ECO:0000305|PubMed:11925432}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G67310.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat shock, UVB, salt, wounding, ethylene, methyl jasmonate, abscisic acid, H(2)O(2) and salicylic acid (PubMed:12218065). Induced by cold stress (PubMed:28351986). {ECO:0000269|PubMed:12218065, ECO:0000269|PubMed:28351986}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G67310
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY5100260.0AY510026.1 Arabidopsis thaliana ethylene-induced calmodulin-binding protein 4 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_176899.20.0Calmodulin-binding transcription activator protein with CG-1 and Ankyrin domain
SwissprotQ9FYG20.0CMTA4_ARATH; Calmodulin-binding transcription activator 4
TrEMBLA0A178WML90.0A0A178WML9_ARATH; Uncharacterized protein
STRINGAT1G67310.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM64762642
Representative plantOGRP5621565
Publications ? help Back to Top
  1. Reddy AS,Reddy VS,Golovkin M
    A calmodulin binding protein from Arabidopsis is induced by ethylene and contains a DNA-binding motif.
    Biochem. Biophys. Res. Commun., 2000. 279(3): p. 762-9
    [PMID:11162426]
  2. Reddy VS,Ali GS,Reddy AS
    Genes encoding calmodulin-binding proteins in the Arabidopsis genome.
    J. Biol. Chem., 2002. 277(12): p. 9840-52
    [PMID:11782485]
  3. Bouch
    A novel family of calmodulin-binding transcription activators in multicellular organisms.
    J. Biol. Chem., 2002. 277(24): p. 21851-61
    [PMID:11925432]
  4. Yang T,Poovaiah BW
    A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants.
    J. Biol. Chem., 2002. 277(47): p. 45049-58
    [PMID:12218065]
  5. Leonhardt N, et al.
    Microarray expression analyses of Arabidopsis guard cells and isolation of a recessive abscisic acid hypersensitive protein phosphatase 2C mutant.
    Plant Cell, 2004. 16(3): p. 596-615
    [PMID:14973164]
  6. Choi MS, et al.
    Isolation of a calmodulin-binding transcription factor from rice (Oryza sativa L.).
    J. Biol. Chem., 2005. 280(49): p. 40820-31
    [PMID:16192280]
  7. Lee BH,Henderson DA,Zhu JK
    The Arabidopsis cold-responsive transcriptome and its regulation by ICE1.
    Plant Cell, 2005. 17(11): p. 3155-75
    [PMID:16214899]
  8. Lei S, et al.
    Towards map-based cloning: fine mapping of a recessive genic male-sterile gene (BnMs2) in Brassica napus L. and syntenic region identification based on the Arabidopsis thaliana genome sequences.
    Theor. Appl. Genet., 2007. 115(5): p. 643-51
    [PMID:17605126]
  9. de la Fuente van Bentem S, et al.
    Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.
    J. Proteome Res., 2008. 7(6): p. 2458-70
    [PMID:18433157]
  10. Jones AM, et al.
    Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis thaliana.
    J Proteomics, 2009. 72(3): p. 439-51
    [PMID:19245862]
  11. Reiland S, et al.
    Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.
    Plant Physiol., 2009. 150(2): p. 889-903
    [PMID:19376835]
  12. Shin R,Jez JM,Basra A,Zhang B,Schachtman DP
    14-3-3 proteins fine-tune plant nutrient metabolism.
    FEBS Lett., 2011. 585(1): p. 143-7
    [PMID:21094157]
  13. Benn G, et al.
    A key general stress response motif is regulated non-uniformly by CAMTA transcription factors.
    Plant J., 2014. 80(1): p. 82-92
    [PMID:25039701]
  14. Kidokoro S, et al.
    Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature.
    Plant Cell, 2017. 29(4): p. 760-774
    [PMID:28351986]