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Plant Transcription
Factor Database
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Transcription Factor Information
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Basic
Information? help
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| TF ID |
AT1G30970.1 |
| Common Name | F17F8.14, SUF4 |
| Organism |
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| Taxonomic ID |
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| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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| Family |
C2H2 |
| Protein Properties |
Length: 367aa MW: 39801.5 Da PI: 8.7845 |
| Description |
C2H2 family protein |
| Gene Model |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | zf-C2H2 | 12.1 | 0.00059 | 36 | 59 | 1 | 23 |
EEETTTTEEESSHHHHHHHHHH.T CS
zf-C2H2 1 ykCpdCgksFsrksnLkrHirt.H 23
+kC+ C+k s+ s ++ H H
AT1G30970.1 36 FKCHVCHKKLSTASGMVIHVLQvH 59
89*****************87656 PP
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| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006355 | Biological Process | regulation of transcription, DNA-templated |
| GO:0009910 | Biological Process | negative regulation of flower development |
| GO:0030154 | Biological Process | cell differentiation |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| GO:0042803 | Molecular Function | protein homodimerization activity |
| GO:0046872 | Molecular Function | metal ion binding |
| GO:0046982 | Molecular Function | protein heterodimerization activity |
| Sequence ? help Back to Top |
| Protein Sequence Length: 367 aa
Download sequence Send
to blast |
MGKKKKRATE KVWCYYCDRE FDDEKILVQH QKAKHFKCHV CHKKLSTASG MVIHVLQVHK 60
ENVTKVPNAK DGRDSTDIEI YGMQGIPPHV LTAHYGEEED EPPAKVAKVE IPSAPLGGVV 120
PRPYGMVYPP QQVPGAVPAR PMYYPGPPMR HPAPVWQMPP PRPQQWYPQN PALSVPPAAH 180
LGYRPQPLFP VQNMGMTPTP TSAPAIQPSP VTGVTPPGIP TSSPAMPVPQ PLFPVVNNSI 240
PSQAPPFSAP LPVGGAQQPS HADALGSADA YPPNNSIPGG TNAHSYASGP NTSGPSIGPP 300
PVIANKAPSN QPNEVYLVWD DEAMSMEERR MSLPKYKVHD ETSQMNSINA AIDRRISESR 360
LAGRMAF
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| Expression -- UniGene
? help Back to Top |
| UniGene ID |
E-value |
Expressed in |
| At.25254 | 0.0 | floral meristem| flower| leaf| root| vegetative tissue |
| Expression --
Description ? help
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| Source |
Description |
| Uniprot | DEVELOPMENTAL STAGE: Barely detectable in 3-days-old seedling, and then increases. {ECO:0000269|PubMed:17138694}. |
| Uniprot | TISSUE SPECIFICITY: Expressed in root, shoot apex, leaves, stem and flowers. Expressed in expanding leaves, in the vasculature of fully expanded leaves, in the inflorescence, throughout young floral primordia, in the carpels of older flowers and in fertilized ovules. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694}. |
| Functional Description ? help
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| Source |
Description |
| TAIR | Encodes SUF4 (SUPPRESSOR of FRI 4), a putative zinc-finger-containing transcription factor that is required for delayed flowering in winter-annual Arabidopsis. suf4 mutations strongly suppress the late-flowering phenotype of FRI (FRIGIDA) mutants. suf4 mutants also show reduced H3K4 trimethylation at FLC (FLOWERING LOCUS C), a floral inhibitor. SUF4 may act to specifically recruit a putative histone H3 methyltransferase EFS (EARLY FLOWERING IN SHORT DAYS) and the PAF1-like complex to the FLC locus. |
| UniProt | Sequence-specific DNA binding factor that recognizes the 5'-CCAAATTTTAAGTTT-3' sequence. Recruits the FRI-C complex to the FLC promoter. Required for FRI-mediated FLC activation, but has no effect on the expression of MAF1, MAF2, MAF3, MAF5, UFC and CO. Dispensable for the reactivation of FLC in early embryogenesis, but required to maintain high levels of FLC expression in later embryonic and vegetative development. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694, ECO:0000269|PubMed:19121105, ECO:0000269|PubMed:21282526}. |
| Function -- GeneRIF ? help
Back to Top |
- SUF4 forms a protein complex with FRI and FRL1 and functions as a transcriptional activator of FLC. [SUF4]
[PMID: 17138694] - MOM1 contributes to the regulation of SUF4 and EC1 gene expression.
[PMID: 27920160]
|
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Not regulated by photoperiod or vernalization. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694}. |
| Phenotype -- Disruption Phenotype ? help
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| Source |
Description |
| UniProt | DISRUPTION PHENOTYPE: Early flowering. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694}. |
| Annotation --
Nucleotide ? help
Back to Top |
| Source |
Hit ID |
E-value |
Description |
| GenBank | AF360277 | 0.0 | AF360277.1 Arabidopsis thaliana putative zinc finger protein (At1g30970) mRNA, complete cds. |
| GenBank | AY051039 | 0.0 | AY051039.1 Arabidopsis thaliana putative zinc finger protein (At1g30970) mRNA, complete cds. |
| Publications
? help Back to Top |
- Riechmann JL, et al.
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Science, 2000. 290(5499): p. 2105-10
[PMID:11118137] - Yamada K, et al.
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Science, 2003. 302(5646): p. 842-6
[PMID:14593172] - Hoth S, et al.
Monitoring genome-wide changes in gene expression in response to endogenous cytokinin reveals targets in Arabidopsis thaliana.
FEBS Lett., 2003. 554(3): p. 373-80
[PMID:14623097] - Gong W, et al.
Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes.
Plant Physiol., 2004. 135(2): p. 773-82
[PMID:15208423] - Kim SY,Michaels SD
SUPPRESSOR OF FRI 4 encodes a nuclear-localized protein that is required for delayed flowering in winter-annual Arabidopsis.
Development, 2006. 133(23): p. 4699-707
[PMID:17079264] - Kim S,Choi K,Park C,Hwang HJ,Lee I
SUPPRESSOR OF FRIGIDA4, encoding a C2H2-Type zinc finger protein, represses flowering by transcriptional activation of Arabidopsis FLOWERING LOCUS C.
Plant Cell, 2006. 18(11): p. 2985-98
[PMID:17138694] - Choi J, et al.
Resetting and regulation of Flowering Locus C expression during Arabidopsis reproductive development.
Plant J., 2009. 57(5): p. 918-31
[PMID:19121105] - Van Leene J, et al.
Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana.
Mol. Syst. Biol., 2010. 6: p. 397
[PMID:20706207] - Ko JH, et al.
Growth habit determination by the balance of histone methylation activities in Arabidopsis.
EMBO J., 2010. 29(18): p. 3208-15
[PMID:20711170] - Choi K, et al.
The FRIGIDA complex activates transcription of FLC, a strong flowering repressor in Arabidopsis, by recruiting chromatin modification factors.
Plant Cell, 2011. 23(1): p. 289-303
[PMID:21282526] - Ding L,Kim SY,Michaels SD
FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis.
Plant Physiol., 2013. 163(1): p. 243-52
[PMID:23899645] - Lai Z, et al.
MED18 interaction with distinct transcription factors regulates multiple plant functions.
Nat Commun, 2014. 5: p. 3064
[PMID:24451981] - Bao Z,Zhang N,Hua J
Endopolyploidization and flowering time are antagonistically regulated by checkpoint component MAD1 and immunity modulator MOS1.
Nat Commun, 2014. 5: p. 5628
[PMID:25429892] - Jin J, et al.
An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
Mol. Biol. Evol., 2015. 32(7): p. 1767-73
[PMID:25750178] - Resentini F, et al.
SUPPRESSOR OF FRIGIDA (SUF4) Supports Gamete Fusion via Regulating Arabidopsis EC1 Gene Expression.
Plant Physiol., 2017. 173(1): p. 155-166
[PMID:27920160]
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