PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

HD-ZIP

Protein Properties

Length: 284aa MW: 31683.7 Da PI: 8.995

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
914971	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	60	3.8e-19	134	188	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++k+q +Le+ F+++++++ +++ LAkklgLt rqV vWFqNrRa+ k 914971 134 RKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTK 188 677889***********************************************98 PP
2	HD-ZIP_I/II	122.8	1.7e-39	134	223	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rlsk+q+++LE++F+e+++L+p++K +la++Lgl++rqv+vWFqnrRARtk+kq+E+d+e+Lkr++++l++en+rLeke +eLr +l 914971 134 RKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTKLKQTEVDCEYLKRCVEKLTDENRRLEKEAAELR-AL 223 69*************************************************************************************9.54 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04618	6.4E-27	2	98	IPR006712	HD-ZIP protein, N-terminal
Gene3D	G3DSA:1.10.10.60	1.5E-18	115	188	IPR009057	Homeodomain-like
SuperFamily	SSF46689	6.68E-19	118	191	IPR009057	Homeodomain-like
PROSITE profile	PS50071	17.135	130	190	IPR001356	Homeobox domain
SMART	SM00389	1.9E-17	132	194	IPR001356	Homeobox domain
CDD	cd00086	4.48E-16	134	191	No hit	No description
Pfam	PF00046	1.5E-16	134	188	IPR001356	Homeobox domain
PRINTS	PR00031	7.5E-6	161	170	IPR000047	Helix-turn-helix motif
PROSITE pattern	PS00027	0	165	188	IPR017970	Homeobox, conserved site
PRINTS	PR00031	7.5E-6	170	186	IPR000047	Helix-turn-helix motif
Pfam	PF02183	8.4E-8	190	224	IPR003106	Leucine zipper, homeobox-associated
SMART	SM00340	1.2E-23	190	233	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010582	Biological Process	floral meristem determinacy
GO:0048467	Biological Process	gynoecium development
GO:0080127	Biological Process	fruit septum development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0043621	Molecular Function	protein self-association

Sequence ? help Back to Top
Protein Sequence Length: 284 aa Download sequence Send to blast
MMMGKEDLGL SLRLGFAQNH HPLQLNLKPT SSSMSNLQMF PWNQTFVSSS DHQKQQSLRK 60 IDVNSLPTTV DLEEETGVSS PNSTISSTVS GKRRSEREGT SGGGAGDDLD ITLDRSSSRG 120 TSDEEEDYGG ETCRKKLRLS KDQSAVLEDT FKEHNTLNPK QKLALAKKLG LTARQVEVWF 180 QNRRARTKLK QTEVDCEYLK RCVEKLTDEN RRLEKEAAEL RALKLSPRLY GQMSPPTTLL 240 MCPSCERVAG PSSSNHNQRS VSLSPWLQMA HGPSTFDVMR PRS*

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	182	190	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00050	PBM	Transfer from AT4G17460	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	914971

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ441252	0.0	AJ441252.1 Arabidopsis thaliana mRNA for homeodomain-leucine zipper protein HAT1.
GenBank	AK228587	0.0	AK228587.1 Arabidopsis thaliana mRNA for homeobox-leucine zipper protein HAT1, complete cds, clone: RAFL15-36-J21.
GenBank	ATU09332	0.0	U09332.1 Arabidopsis thaliana clone HAT1 homeobox protein mRNA, complete cds.
GenBank	AY087322	0.0	AY087322.1 Arabidopsis thaliana clone 34167 mRNA, complete sequence.
GenBank	BT005756	0.0	BT005756.1 Arabidopsis thaliana clone RAFL15-36-J21 (R50164) putative homeobox-leucine zipper protein HAT1 (HD-Zip protein 1) (At4g17460) mRNA, complete cds.
GenBank	BT006112	0.0	BT006112.1 Arabidopsis thaliana clone U50164 putative homeobox-leucine zipper protein HAT1 (HD-Zip protein 1) (At4g17460) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002870101.1	0.0	homeobox-leucine zipper protein HAT1
Swissprot	P46600	0.0	HAT1_ARATH; Homeobox-leucine zipper protein HAT1
TrEMBL	D7MBY6	0.0	D7MBY6_ARALL; Homeobox-leucine zipper protein HAT1
STRING	scaffold_702713.1	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1563	26	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17460.1	1e-162	Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein

Link Out ? help Back to Top
Phytozome	914971
Entrez Gene	9304137

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Zou LJ, et al. Role of Transcription Factor HAT1 in Modulating Arabidopsis thaliana Response to Cucumber mosaic virus. Plant Cell Physiol., 2016. 57(9): p. 1879-89 [PMID:27328697] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Tan W, et al. Transcription factor HAT1 is a substrate of SnRK2.3 kinase and negatively regulates ABA synthesis and signaling in Arabidopsis responding to drought. PLoS Genet., 2018. 14(4): p. e1007336 [PMID:29659577]