PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 141aa MW: 16221.3 Da PI: 7.6105

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
879201	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	34.7	3.3e-11	57	105	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L+el+P + +k Ka +L + ++YI+sLq 879201 57 NSHSLAERVRREKISERMRLLQELVPGC----NKITGKAFMLDEIINYIQSLQ 105 58************************....999***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	4.71E-18	51	120	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.17E-8	52	109	No hit	No description
PROSITE profile	PS50888	15.44	54	104	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.0E-17	55	122	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	2.0E-8	57	105	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.2E-9	60	110	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 141 aa Download sequence Send to blast
KAVEEFQEDP QSGSDQSQKK HKNDQSKETM NKESSQNEEE PKEKYIHMRA RRGQATNSHS 60 LAERVRREKI SERMRLLQEL VPGCNKITGK AFMLDEIINY IQSLQQQVEF LSMKLATVNP 120 DINIDIDRIL AKDVRAQNPP *

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (PubMed:24130508). {ECO:0000269\|PubMed:23161888, ECO:0000269\|PubMed:24130508}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	879201

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK221806	0.0	AK221806.1 Arabidopsis thaliana mRNA for bHLH transcription factor like protein, complete cds, clone: RAFL21-86-B04.
GenBank	AK229309	0.0	AK229309.1 Arabidopsis thaliana mRNA for bHLH transcription factor like protein, partial cds, clone: RAFL16-57-I01.
GenBank	BT012655	0.0	BT012655.1 Arabidopsis thaliana At1g10120 gene, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002892548.1	5e-85	transcription factor bHLH74
Refseq	XP_006417495.1	6e-85	transcription factor bHLH74
Swissprot	Q6NKN9	2e-85	BH074_ARATH; Transcription factor bHLH74
TrEMBL	D7KKK3	1e-98	D7KKK3_ARALL; Predicted protein (Fragment)
STRING	Al_scaffold_0001_968	2e-99	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5196	28	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G10120.1	8e-88	bHLH family protein

Link Out ? help Back to Top
Phytozome	879201
Entrez Gene	9325844

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]