PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

MYB

Protein Properties

Length: 339aa MW: 38079.4 Da PI: 5.4615

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
861189	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	52.6	1e-16	14	61	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT eEd++l+ +++ +G g W+ I+++ g++R++k+c++rw +yl 861189 14 KGAWTIEEDKKLISYIHDHGEGGWRDIPEKAGLKRCGKSCRLRWTNYL 61 79********************************************97 PP
2	Myb_DNA-binding	49.2	1.2e-15	67	112	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg ++ eE+++++ +++ G++ W+tIar+++ +Rt++++k++w+++l 861189 67 RGEFSYEEEQIIIMLHASRGNK-WSTIARHLP-KRTDNEVKNYWNTHL 112 899*****************.*****.**********996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	3.0E-23	6	64	IPR009057	Homeodomain-like
PROSITE profile	PS51294	17.555	9	61	IPR017930	Myb domain
SuperFamily	SSF46689	2.24E-28	11	108	IPR009057	Homeodomain-like
SMART	SM00717	1.0E-12	13	63	IPR001005	SANT/Myb domain
Pfam	PF00249	9.3E-16	14	61	IPR001005	SANT/Myb domain
CDD	cd00167	5.83E-10	16	61	No hit	No description
PROSITE profile	PS51294	24.21	62	116	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	3.0E-25	65	116	IPR009057	Homeodomain-like
SMART	SM00717	2.1E-13	66	114	IPR001005	SANT/Myb domain
Pfam	PF00249	1.1E-13	67	112	IPR001005	SANT/Myb domain
CDD	cd00167	9.94E-10	69	112	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0009611	Biological Process	response to wounding
GO:0009625	Biological Process	response to insect
GO:0009733	Biological Process	response to auxin
GO:0009753	Biological Process	response to jasmonic acid
GO:0010439	Biological Process	regulation of glucosinolate biosynthetic process
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 339 aa Download sequence Send to blast
MSKRLCCIGE GLKKGAWTIE EDKKLISYIH DHGEGGWRDI PEKAGLKRCG KSCRLRWTNY 60 LKPDIKRGEF SYEEEQIIIM LHASRGNKWS TIARHLPKRT DNEVKNYWNT HLKKRLIDNG 120 IDPVTHKPLD SSNPGSAVPK KFDCQDKSIP DEHSVQWSST TPASLPLSST FNSVKPKISS 180 GETQIESGFL RCKKRFERSS STSRLLNKVA ARASSIGNIL STSIEGTLSS PASSSCLPDS 240 FSQSSEHMID NKEDLSTSID INIPEYDFPQ FLEQFINDDD EAENTGGSNQ DLLMSDVPST 300 FVDEDDIIGD ITSWSTYLLD HPNFMYKSDQ DSEEKNFL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	3e-24	12	116	25	128	MYB TRANSFORMING PROTEIN
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Plays a role in determining the spatial distribution of aliphatic glucosinolates (AGLSs) within the leaf, mostly short chained. Together with MYB28/HAG1 and MYB29/HAG3, promotes aliphatic glucosinolate biosynthesis and represses indolic glucosinolate biosynthesis, but could not activate AGSL biosynthesis on its own. {ECO:0000269\|PubMed:18042203, ECO:0000269\|PubMed:20348214, ECO:0000269\|PubMed:23792303, ECO:0000269\|PubMed:23943862}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	861189

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by auxin (IAA) and jasmonic acid (JA). Accumulates upon mechanical stimuli (e.g. wounding) in inflorescence. Down-regulated by sulfur-deficient stress. {ECO:0000269\|PubMed:16463103, ECO:0000269\|PubMed:18042203, ECO:0000269\|PubMed:23792303}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF175992	0.0	AF175992.1 Arabidopsis thaliana putative transcription factor (MYB76) mRNA, complete cds.
GenBank	DQ446930	0.0	DQ446930.1 Arabidopsis thaliana clone pENTR221-At5g07700 myb family transcription factor (At5g07700) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002871286.1	0.0	transcription factor MYB76
Refseq	XP_020876086.1	0.0	transcription factor MYB76
Swissprot	Q9SPG5	0.0	MYB76_ARATH; Transcription factor MYB76
TrEMBL	D7M0L7	0.0	D7M0L7_ARALL; Predicted protein
STRING	Al_scaffold_0006_698	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3787	18	60

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G07700.1	0.0	myb domain protein 76

Link Out ? help Back to Top
Phytozome	861189
Entrez Gene	9307356

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Frerigmann H,Gigolashvili T Update on the role of R2R3-MYBs in the regulation of glucosinolates upon sulfur deficiency. Front Plant Sci, 2014. 5: p. 626 [PMID:25426131] Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors. Plant Physiol. Biochem., 2016. 102: p. 70-9 [PMID:26913794] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]