PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Utricularia

Family

bHLH

Protein Properties

Length: 222aa MW: 24884.4 Da PI: 5.0761

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
678349697	genome	UGSP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.2	6.9e-09	74	120	5	54
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 + +rEr RR+++N++f eL +l + + K +K + L A++ +++L 678349697 74 KAIRERLRREKLNERFLELSAILEPG---RPVKADKLALLGDAIKLLSQL 120 679********************8...89**************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.163	69	120	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.52E-6	73	125	No hit	No description
Pfam	PF00010	2.7E-6	73	120	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	2.0E-8	75	126	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.71E-11	75	147	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.5E-10	76	141	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 222 aa Download sequence Send to blast
MDSAGLEEWM DMIDCGSLLN DTGEAPDLDW NTQNNCVALE AAIAGTPSHE SECTEKGCTR 60 KRARSDLCSG IGSKAIRERL RREKLNERFL ELSAILEPGR PVKADKLALL GDAIKLLSQL 120 RAESQDYKET NEKLLEEIKC LKAEKNELRQ EKQVLKAEKE LIEQRLKAMS TPGFIPAIPS 180 LYQANFNKVS MIPSYGLVPM WQYLPPATRD TSQDHELRPP AA

Cis-element ? help Back to Top
Source	Link
PlantRegMap	678349697

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011073517.1	6e-97	transcription factor bHLH104
Swissprot	Q8L467	3e-69	BH104_ARATH; Transcription factor bHLH104
TrEMBL	A0A2R6RUR3	7e-87	A0A2R6RUR3_ACTCH; Transcription factor bHLH104 like
STRING	Migut.G00474.1.p	2e-86	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4762	21	32

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.2	6e-58	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]