PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bHLH

Protein Properties

Length: 499aa MW: 54865.3 Da PI: 7.0432

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676782186	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26	1.6e-08	317	364	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq 676782186 317 SHSLAERVRREKIGERMKLLQDLVPGC----NKVTGKALMLDEIINYVQSLQ 364 8***********************9....677***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	2.75E-16	311	377	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.64E-9	311	368	No hit	No description
PROSITE profile	PS50888	15.37	313	363	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.3E-16	313	378	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.1E-5	317	364	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.7E-10	319	369	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009637	Biological Process	response to blue light
GO:0005634	Cellular Component	nucleus
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 499 aa Download sequence Send to blast
MDNELFMHTE LPPPPEMAVH FEQPSSSSAM LNWALMDPNL ARNSPPQDCF PWEKSTQQQQ 60 QQQSIFDSAL SSLVSSPTPS NSNFSGGDGF IIRELIGKLG NIGNSSGEIY GGATMGNNNG 120 KVSRSASCYA TPMSSPPPPM MNRTTPLTEF SGDPGFAERA ARFSCFGSRS FNGRTNSGIP 180 VNNGKMINSG KLTRVSSTPA LNALASPMMI PAGDSTPKLP GEFSRKRKSV SKGKSKENPL 240 STASPSPTFS KTAERKGDWD GKVSKVSQEE KGGKRRREDQ EEEEEEEEGN KSNNTKPPEP 300 PKDYIHVRAR RGQATDSHSL AERVRREKIG ERMKLLQDLV PGCNKVTGKA LMLDEIINYV 360 QSLQRQVEFL SMKLSSVNDT RLEFNVDALV SKDVMIPSSS NRLHESGLAS ESLSHHNYNN 420 HSQLHTSHVS STNMMLHSPM NSLETSTLAR GFTHLPTLTQ FTDSISQYQM FSEEDLQSIV 480 GMGVAHNPNH ESQNMKIEL

Sequence ? help Back to Top

Protein Sequence Length: 499 aa Download sequence Send to blast

MDNELFMHTE LPPPPEMAVH FEQPSSSSAM LNWALMDPNL ARNSPPQDCF PWEKSTQQQQ  60
QQQSIFDSAL SSLVSSPTPS NSNFSGGDGF IIRELIGKLG NIGNSSGEIY GGATMGNNNG  120
KVSRSASCYA TPMSSPPPPM MNRTTPLTEF SGDPGFAERA ARFSCFGSRS FNGRTNSGIP  180
VNNGKMINSG KLTRVSSTPA LNALASPMMI PAGDSTPKLP GEFSRKRKSV SKGKSKENPL  240
STASPSPTFS KTAERKGDWD GKVSKVSQEE KGGKRRREDQ EEEEEEEEGN KSNNTKPPEP  300
PKDYIHVRAR RGQATDSHSL AERVRREKIG ERMKLLQDLV PGCNKVTGKA LMLDEIINYV  360
QSLQRQVEFL SMKLSSVNDT RLEFNVDALV SKDVMIPSSS NRLHESGLAS ESLSHHNYNN  420
HSQLHTSHVS STNMMLHSPM NSLETSTLAR GFTHLPTLTQ FTDSISQYQM FSEEDLQSIV  480
GMGVAHNPNH ESQNMKIEL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	223	228	SRKRKS

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds DNA to G box 5'-CACGTG-3' and to E-box 5'-CANNTG-3' (By similarity). Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (PubMed:24130508). {ECO:0000250\|UniProtKB:Q8GY61, ECO:0000269\|PubMed:24130508}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00036	PBM	Transfer from AT5G48560	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676782186

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488610	0.0	AF488610.1 Arabidopsis thaliana clone bHLH078 putative bHLH transcription factor mRNA, complete cds.
GenBank	BT002945	0.0	BT002945.1 Arabidopsis thaliana clone RAFL14-96-A17 (R20245) unknown protein (At5g48560) mRNA, complete cds.
GenBank	BT005637	0.0	BT005637.1 Arabidopsis thaliana clone U20245 unknown protein (At5g48560) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013593916.1	0.0	PREDICTED: transcription factor bHLH78
Refseq	XP_013593917.1	0.0	PREDICTED: transcription factor bHLH78
Swissprot	Q9FJL4	0.0	BH078_ARATH; Transcription factor bHLH78
TrEMBL	A0A0D3DBT1	0.0	A0A0D3DBT1_BRAOL; Uncharacterized protein
STRING	Bo7g089350.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2332	27	75

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G48560.1	0.0	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281]