PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

C3H

Protein Properties

Length: 582aa MW: 63358.2 Da PI: 6.4522

Description

C3H family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676776610	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-CCCH	17.3	8.7e-06	99	119	5	26
--SGGGGTS--TTTTT-SS-SS CS zf-CCCH 5 lCrffartGtCkyGdrCkFaHg 26 +C+ff + G+C G++C+F H+ 676776610 99 PCKFFGQ-GWCAKGNSCRFLHV 119 7****.***********6 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50103	14.22	94	121	IPR000571	Zinc finger, CCCH-type
SuperFamily	SSF90229	2.62E-6	94	118	IPR000571	Zinc finger, CCCH-type
Gene3D	G3DSA:4.10.1000.10	4.3E-4	99	119	IPR000571	Zinc finger, CCCH-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010220	Biological Process	positive regulation of vernalization response
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 582 aa Download sequence Send to blast
MSDSDMDIDD DEVQVQVQQH TIAGPIEASD SQNDVKKHSD EQSKIIKDSI GNSQPIISGN 60 SGKNIILEGV KGTVLSRFPA PPQSFPPGNG PEQKRAALPC KFFGQGWCAK GNSCRFLHVN 120 EITNRTSQQQ AEINMAGTSG VQSLEERRSL ESKEGGRFPL LGQNGVTSLV NPSGGQRVFP 180 FTNEMRFMPL LDNMGRGSLQ KCGAVFTENR PGFVNSISSF PLRSSFVQEH GSSIASYRQP 240 DMGSTIPSYK QTDMGSSGPA WTGSVFSSAP MNQYASPLGN FENRNNMNGS GSLPMVQATS 300 VSSGQDAEVD TTSDKKKVSS NDWEPSEPFR ASFTIPPYIL PSSDALYDPF TDTENPDHRS 360 LNAPSPSKEK DAHKKSGQQK DGDSASGPQA QDCNNDDKNS SCSQNQFQET VGRKNLEEHG 420 VVEGVATSVV DQNDATTPSK EVSSSAAAEN RVVLKRSKPA GHESWHRSDG SSHQKVLKSE 480 EVDGEVRSDA GTKVMRQFRT AVVETIKEML KPLWREGRLT KDVHNMVVKR ATEKIVSAAV 540 QFRQVPTNTE SVEQYLSMSA PKIVKLVEGY VEKYGKPQGT IK

Sequence ? help Back to Top

Protein Sequence Length: 582 aa Download sequence Send to blast

MSDSDMDIDD DEVQVQVQQH TIAGPIEASD SQNDVKKHSD EQSKIIKDSI GNSQPIISGN  60
SGKNIILEGV KGTVLSRFPA PPQSFPPGNG PEQKRAALPC KFFGQGWCAK GNSCRFLHVN  120
EITNRTSQQQ AEINMAGTSG VQSLEERRSL ESKEGGRFPL LGQNGVTSLV NPSGGQRVFP  180
FTNEMRFMPL LDNMGRGSLQ KCGAVFTENR PGFVNSISSF PLRSSFVQEH GSSIASYRQP  240
DMGSTIPSYK QTDMGSSGPA WTGSVFSSAP MNQYASPLGN FENRNNMNGS GSLPMVQATS  300
VSSGQDAEVD TTSDKKKVSS NDWEPSEPFR ASFTIPPYIL PSSDALYDPF TDTENPDHRS  360
LNAPSPSKEK DAHKKSGQQK DGDSASGPQA QDCNNDDKNS SCSQNQFQET VGRKNLEEHG  420
VVEGVATSVV DQNDATTPSK EVSSSAAAEN RVVLKRSKPA GHESWHRSDG SSHQKVLKSE  480
EVDGEVRSDA GTKVMRQFRT AVVETIKEML KPLWREGRLT KDVHNMVVKR ATEKIVSAAV  540
QFRQVPTNTE SVEQYLSMSA PKIVKLVEGY VEKYGKPQGT IK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in the FRIGIDA-mediated vernalization pathway, but not in the autonomous flowering pathway. Acts cooperatively with FRI (FRIGIDA) or FRL1 (FRIGIDA-LIKE 1) to promote FLC (FLOWERING LOCUS C) expression. Required for the stabilization of the FRI-C complex. {ECO:0000269\|PubMed:16291783, ECO:0000269\|PubMed:21282526}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676776610

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013637217.1	0.0	PREDICTED: protein FRIGIDA-ESSENTIAL 1
Swissprot	Q84VG7	0.0	FES1_ARATH; Protein FRIGIDA-ESSENTIAL 1
TrEMBL	A0A0D3BSB9	0.0	A0A0D3BSB9_BRAOL; Uncharacterized protein
STRING	Bo4g042370.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM13468	15	21

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G33835.1	0.0	C3H family protein

Publications ? help Back to Top
Ding L,Kim SY,Michaels SD FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis. Plant Physiol., 2013. 163(1): p. 243-52 [PMID:23899645]