PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676765022

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bZIP

Protein Properties

Length: 680aa MW: 74172.1 Da PI: 6.1874

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676765022	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	42.7	1.3e-13	188	248	2	62
XXXCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 2 kelkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkeleelkkevaklkse 62 + k+ r ++NRe+A+ sR+RKk+++eeL+ kvk++++ +L +++ e a+lk++ 676765022 188 DDEKKKVRQIRNRESAQLSRLRKKQYVEELQGKVKSMSSTIAELSGKISYVMAENAALKQQ 248 567999****************************************************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	7.1E-16	181	251	No hit	No description
SMART	SM00338	4.5E-16	187	251	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	10.243	189	252	IPR004827	Basic-leucine zipper domain
Pfam	PF00170	7.1E-11	191	249	IPR004827	Basic-leucine zipper domain
SuperFamily	SSF57959	6.88E-12	191	249	No hit	No description
CDD	cd14704	7.52E-16	192	243	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006990	Biological Process	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0009408	Biological Process	response to heat
GO:0005635	Cellular Component	nuclear envelope
GO:0005654	Cellular Component	nucleoplasm
GO:0005783	Cellular Component	endoplasmic reticulum
GO:0016020	Cellular Component	membrane
GO:0048471	Cellular Component	perinuclear region of cytoplasm
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 680 aa Download sequence Send to blast
MTESTSVIAH PPEMADLNPN MLSDSEMLSV PPLDPLFLSC SDPISMDSSI PDLDFLLDDE 60 NGGFEGLDIS FDDFFDYTFD VETPPVISEE FGSSADQSPE AIENHANLDS EGRSDSVHSQ 120 VSSQGSKSFA SGACDTVDAL SSPDPDSTSH QKSSVSKRKK ERGDSGGEYR SFKYQKSDDK 180 SAAPVEEDDE KKKVRQIRNR ESAQLSRLRK KQYVEELQGK VKSMSSTIAE LSGKISYVMA 240 ENAALKQQMA AASGAPPPVN PYMPAPPLPY QWMPYPYYPV RGYGSQTPLV PIPKLDPKPG 300 SGSRSKKPES KKNEGKSKLK KVASISFIGI LFFIFLFGTL VPFMDVNYGE GSGSFSGLSK 360 YEGRRYYDEH RGKVLMVGHG SDVRRDSRIS EGNIHPSRRS HGERDSCGGV EYNGHPNVEG 420 RPSPLSNSSE LLFASLYVPR NDGLVKIDGN LIIHSVLASE KATDFAKKNI SEKIKSEEPD 480 LSIPGALSSA LAAPDVRGNG AMLPHKPKAL SSGSPEGKKL HQWFHEGGSG TLMDYSMCTE 540 VFQFEIAPGA IVPSSASNIT REHLQNVTTH DKRMKNRRTL EGIPVSLVAS ELNITETQSN 600 KDAQNKSFHG KADTKPTSSS SMVVSVLLDP REIVDSETDR VLPSNSKSLS RIFVVVLLDS 660 VKYVTYSCVL PRSGLHLVAT

Sequence ? help Back to Top

Protein Sequence Length: 680 aa Download sequence Send to blast

MTESTSVIAH PPEMADLNPN MLSDSEMLSV PPLDPLFLSC SDPISMDSSI PDLDFLLDDE  60
NGGFEGLDIS FDDFFDYTFD VETPPVISEE FGSSADQSPE AIENHANLDS EGRSDSVHSQ  120
VSSQGSKSFA SGACDTVDAL SSPDPDSTSH QKSSVSKRKK ERGDSGGEYR SFKYQKSDDK  180
SAAPVEEDDE KKKVRQIRNR ESAQLSRLRK KQYVEELQGK VKSMSSTIAE LSGKISYVMA  240
ENAALKQQMA AASGAPPPVN PYMPAPPLPY QWMPYPYYPV RGYGSQTPLV PIPKLDPKPG  300
SGSRSKKPES KKNEGKSKLK KVASISFIGI LFFIFLFGTL VPFMDVNYGE GSGSFSGLSK  360
YEGRRYYDEH RGKVLMVGHG SDVRRDSRIS EGNIHPSRRS HGERDSCGGV EYNGHPNVEG  420
RPSPLSNSSE LLFASLYVPR NDGLVKIDGN LIIHSVLASE KATDFAKKNI SEKIKSEEPD  480
LSIPGALSSA LAAPDVRGNG AMLPHKPKAL SSGSPEGKKL HQWFHEGGSG TLMDYSMCTE  540
VFQFEIAPGA IVPSSASNIT REHLQNVTTH DKRMKNRRTL EGIPVSLVAS ELNITETQSN  600
KDAQNKSFHG KADTKPTSSS SMVVSVLLDP REIVDSETDR VLPSNSKSLS RIFVVVLLDS  660
VKYVTYSCVL PRSGLHLVAT

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in ER stress responses. Functions as a stress sensor and transducer in ER stress signaling pathway. After proteolysis by SBT6.1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872). Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872). {ECO:0000269\|PubMed:18156219, ECO:0000269\|PubMed:18634751, ECO:0000269\|PubMed:18849477, ECO:0000269\|PubMed:20876872}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00345	DAP	Transfer from AT3G10800	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676765022

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock. {ECO:0000269\|PubMed:18849477}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006407504.1	0.0	bZIP transcription factor 28
Swissprot	Q9SG86	0.0	BZP28_ARATH; bZIP transcription factor 28
TrEMBL	E4MX70	0.0	E4MX70_EUTHA; mRNA, clone: RTFL01-21-B04
TrEMBL	V4M298	0.0	V4M298_EUTSA; Uncharacterized protein
STRING	XP_006407504.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14397	18	22

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10800.1	0.0	bZIP family protein

Publications ? help Back to Top
Deng Y,Srivastava R,Howell SH Protein kinase and ribonuclease domains of IRE1 confer stress tolerance, vegetative growth, and reproductive development in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. 19633-8 [PMID:24145452] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis. Plant Cell Physiol., 2014. 55(10): p. 1772-8 [PMID:25138441] Sun L,Zhang SS,Lu SJ,Liu JX Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis. Sci China Life Sci, 2015. 58(3): p. 270-5 [PMID:25634523] Zhang L,Chen H,Brandizzi F,Verchot J,Wang A The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast. PLoS Genet., 2015. 11(4): p. e1005164 [PMID:25875739] Ma ZX, et al. The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis. PLoS ONE, 2015. 10(7): p. e0132500 [PMID:26186593] Sagor GH, et al. The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis. Front Plant Sci, 2015. 6: p. 687 [PMID:26442007] Kørner CJ,Du X,Vollmer ME,Pajerowska-Mukhtar KM Endoplasmic Reticulum Stress Signaling in Plant Immunity--At the Crossroad of Life and Death. Int J Mol Sci, 2015. 16(11): p. 26582-98 [PMID:26556351] Zeng Y, et al. Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(46): p. 14360-5 [PMID:26578783] Meng Z,Ruberti C,Gong Z,Brandizzi F CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses. Plant J., 2017. 89(3): p. 486-501 [PMID:27747970] Nawkar GM, et al. HY5, a positive regulator of light signaling, negatively controls the unfolded protein response in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(8): p. 2084-2089 [PMID:28167764] Iwata Y, et al. Activation of the Arabidopsis membrane-bound transcription factor bZIP28 is mediated by site-2 protease, but not site-1 protease. Plant J., 2017. 91(3): p. 408-415 [PMID:28407373] Zhang SS, et al. Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis. Plant Cell, 2017. 29(5): p. 1007-1023 [PMID:28442596] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Ruberti C,Lai Y,Brandizzi F Recovery from temporary endoplasmic reticulum stress in plants relies on the tissue-specific and largely independent roles of bZIP28 and bZIP60, as well as an antagonizing function of BAX-Inhibitor 1 upon the pro-adaptive signaling mediated by bZIP28. Plant J., 2018. 93(1): p. 155-165 [PMID:29124827] Kim JS,Yamaguchi-Shinozaki K,Shinozaki K ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation. Plant Physiol., 2018. 176(3): p. 2221-2230 [PMID:29367234]