PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bHLH

Protein Properties

Length: 495aa MW: 55673.3 Da PI: 7.1404

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676747288	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	11.8	0.00047	27	53	10	39
HHHHHHHHHHHHHHHCTSCCC...TTS-ST CS HLH 10 rrRRdriNsafeeLrellPkaskapskKls 39 r RR++iN+++ +L lP+ +++Kl+ 676747288 27 RERREQINQSLMKLSFSLPSK---SKPKLT 53 89******************8...788864 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF12656	1.5E-22	160	233	IPR026822	Spp2/MOS2, G-patch domain
SMART	SM00443	1.1E-6	185	231	IPR000467	G-patch domain
PROSITE profile	PS50174	11.433	187	233	IPR000467	G-patch domain
SMART	SM00739	0.013	264	291	IPR005824	KOW
SMART	SM00739	0.13	434	461	IPR005824	KOW
CDD	cd13153	2.86E-13	438	488	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009870	Biological Process	defense response signaling pathway, resistance gene-dependent
GO:0042742	Biological Process	defense response to bacterium
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding

Sequence ? help Back to Top
Protein Sequence Length: 495 aa Download sequence Send to blast
MYLRTPKSPT EFNLCDSHRL SVYVPVRERR EQINQSLMKL SFSLPSKSKP KLTSTTDVNN 60 NNAVNDGNSK EFVTEFDPSK TLTDSTPKHV IPPIENTWRP HKKMKNIDLP FQSSNTGSGL 120 EFEPEVPSTE GSDNNITYGL KLRQKVVKEE DQKLQAPLEQ LMLQSLRKDL ESLADDPTLE 180 DFESVPVDGF GAALMAGYGW KPGKGIGKNA KEDVEIKEYK KWTAKEGLGF DLDRSKVVVD 240 TKAKVKESLK LESKGRGFGD GGDLFFVGKE VRIVGGRDMG LKGKIVEKVG SDLFVVKISG 300 SDDEVEVGVD EVADLGSQEE EKCLKKLKDL QLKDKEKVDK RSRGTEREKS RNEVRVSEKH 360 DRSQTRERRV KKQPSWLRSH IKVRIVSKDL KGGRLYLKKG KVVDVVGPTT CDITMDETQE 420 LVQGVDQELL ETALPRRGGP VLVLSGKYKG VYGNLVEKDL DKETGVVRDL DNHKMLDVRL 480 EQVAEYMGDM DDIEY

Sequence ? help Back to Top

Protein Sequence Length: 495 aa Download sequence Send to blast

MYLRTPKSPT EFNLCDSHRL SVYVPVRERR EQINQSLMKL SFSLPSKSKP KLTSTTDVNN  60
NNAVNDGNSK EFVTEFDPSK TLTDSTPKHV IPPIENTWRP HKKMKNIDLP FQSSNTGSGL  120
EFEPEVPSTE GSDNNITYGL KLRQKVVKEE DQKLQAPLEQ LMLQSLRKDL ESLADDPTLE  180
DFESVPVDGF GAALMAGYGW KPGKGIGKNA KEDVEIKEYK KWTAKEGLGF DLDRSKVVVD  240
TKAKVKESLK LESKGRGFGD GGDLFFVGKE VRIVGGRDMG LKGKIVEKVG SDLFVVKISG  300
SDDEVEVGVD EVADLGSQEE EKCLKKLKDL QLKDKEKVDK RSRGTEREKS RNEVRVSEKH  360
DRSQTRERRV KKQPSWLRSH IKVRIVSKDL KGGRLYLKKG KVVDVVGPTT CDITMDETQE  420
LVQGVDQELL ETALPRRGGP VLVLSGKYKG VYGNLVEKDL DKETGVVRDL DNHKMLDVRL  480
EQVAEYMGDM DDIEY

Functional Description ? help Back to Top
Source	Description
UniProt	Required for innate and induced resistance to pathogens such as compatible and incompatible isolates of P.syringae and P.parasitica. {ECO:0000269\|PubMed:16271871}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676747288

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006415079.1	0.0	protein MOS2
Swissprot	Q9C801	0.0	MOS2_ARATH; Protein MOS2
TrEMBL	A0A1J3ERD8	0.0	A0A1J3ERD8_NOCCA; Protein MOS2 (Fragment)
STRING	XP_006415079.1	0.0	(Eutrema salsugineum)

Publications ? help Back to Top
Zhang Y,Cheng YT,Bi D,Palma K,Li X MOS2, a protein containing G-patch and KOW motifs, is essential for innate immunity in Arabidopsis thaliana. Curr. Biol., 2005. 15(21): p. 1936-42 [PMID:16271871] Wu X, et al. A role for the RNA-binding protein MOS2 in microRNA maturation in Arabidopsis. Cell Res., 2013. 23(5): p. 645-57 [PMID:23399598] Copeland C,Xu S,Qi Y,Li X MOS2 has redundant function with its homolog MOS2H and is required for proper splicing of SNC1. Plant Signal Behav, 2014. [PMID:23803746] Zang S, et al. GPKOW is essential for pre-mRNA splicing in vitro and suppresses splicing defect caused by dominant-negative DHX16 mutation in vivo. Biosci. Rep., 2014. 34(6): p. e00163 [PMID:25296192] Zhang R,Qi H,Sun Y,Xiao S,Lim BL Transgenic Arabidopsis thaliana containing increased levels of ATP and sucrose is more susceptible to Pseudomonas syringae. PLoS ONE, 2017. 12(2): p. e0171040 [PMID:28152090]