PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bHLH

Protein Properties

Length: 504aa MW: 54207.6 Da PI: 5.7595

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676738810	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	27.3	6.4e-09	330	378	3	55
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq 676738810 330 NSHSLAERVRREKISERMKFLQDLVPGC----NKVTGKAVMLDEIINYVQSLQ 378 58***********************9....677***************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	3.93E-11	325	382	No hit	No description
SuperFamily	SSF47459	2.75E-17	325	396	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	15.478	327	377	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.5E-17	328	395	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.2E-6	330	378	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.5E-10	333	383	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 504 aa Download sequence Send to blast
MDISEKDEFS GEKRNGDATT VNYHDSANNP PADWRVSGSN PVSAPIDSYP QENLISACAS 60 SCSPSQMMES FGQTLWYDPT NVQAVGGYGG FNGGNASSSS SFRGNMDRSL EMGWNLPNLL 120 PPKGNGLFLP NASSFLPPSM AQFPADSGFI ERAARFSLFS GGNFSDMVNQ QPLGNPESIG 180 LFLQGGGTMQ GQCPSNEVNV GVAHNDASTA MKDPNVRSSE QANKPNVPGS GNVSEDTQSS 240 GGNGQKGGET SSKGVDSKKR KRNRQNPEAD RSQQSEEEQD NNGGDKKRND EQSPNSQGNK 300 TNSGKQQGKQ TSDPKDGYIH VRARRGQATN SHSLAERVRR EKISERMKFL QDLVPGCNKV 360 TGKAVMLDEI INYVQSLQRQ VEFLSMKLAT VNPQMDFNLE GLLAKDALQL RAGSSSATPF 420 PQNMSMVYPP LPHGFMQQTL SSIGRTVSSP LSPMNGGYKR QETNGWEGDL QNVIHINYGA 480 GDVPPDPQAA ATASLPSSNM KVEP

Sequence ? help Back to Top

Protein Sequence Length: 504 aa Download sequence Send to blast

MDISEKDEFS GEKRNGDATT VNYHDSANNP PADWRVSGSN PVSAPIDSYP QENLISACAS  60
SCSPSQMMES FGQTLWYDPT NVQAVGGYGG FNGGNASSSS SFRGNMDRSL EMGWNLPNLL  120
PPKGNGLFLP NASSFLPPSM AQFPADSGFI ERAARFSLFS GGNFSDMVNQ QPLGNPESIG  180
LFLQGGGTMQ GQCPSNEVNV GVAHNDASTA MKDPNVRSSE QANKPNVPGS GNVSEDTQSS  240
GGNGQKGGET SSKGVDSKKR KRNRQNPEAD RSQQSEEEQD NNGGDKKRND EQSPNSQGNK  300
TNSGKQQGKQ TSDPKDGYIH VRARRGQATN SHSLAERVRR EKISERMKFL QDLVPGCNKV  360
TGKAVMLDEI INYVQSLQRQ VEFLSMKLAT VNPQMDFNLE GLLAKDALQL RAGSSSATPF  420
PQNMSMVYPP LPHGFMQQTL SSIGRTVSSP LSPMNGGYKR QETNGWEGDL QNVIHINYGA  480
GDVPPDPQAA ATASLPSSNM KVEP

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator involved in cell elongation. Regulates the expression of a subset of genes involved in cell expansion by binding to the G-box motif. {ECO:0000269\|PubMed:23161888}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676738810

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK318937	0.0	AK318937.1 Arabidopsis thaliana AT1G68920 mRNA, complete cds, clone: RAFL22-22-I01.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006391072.1	0.0	transcription factor bHLH49
Swissprot	Q9CAA9	0.0	BH049_ARATH; Transcription factor bHLH49
TrEMBL	V4KM38	0.0	V4KM38_EUTSA; Uncharacterized protein
STRING	XP_006391072.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5900	25	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G68920.3	0.0	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Tian C, et al. An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation. Mol. Syst. Biol., 2014. 10: p. 755 [PMID:25358340] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]