PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

WRKY

Protein Properties

Length: 339aa MW: 37807.8 Da PI: 6.5136

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676734888	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	105.5	2.7e-33	178	234	2	58
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnh 58 +Dgy+WrKYGqK vk+s+fprsYYrCt+a+C+vkk+vers +dp++v++tYeg+H+h 676734888 178 EDGYRWRKYGQKAVKNSPFPRSYYRCTTASCNVKKRVERSFRDPSTVVTTYEGQHTH 234 8******************************************************** PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF038130	5.6E-116	1	339	IPR017396	PWRKY transcription factor, group IIc
Gene3D	G3DSA:2.20.25.80	8.0E-34	162	236	IPR003657	WRKY domain
SuperFamily	SSF118290	1.7E-28	169	235	IPR003657	WRKY domain
PROSITE profile	PS50811	30.963	172	237	IPR003657	WRKY domain
SMART	SM00774	1.0E-38	177	236	IPR003657	WRKY domain
Pfam	PF03106	7.7E-26	178	234	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009624	Biological Process	response to nematode
GO:0009733	Biological Process	response to auxin
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 339 aa Download sequence Send to blast
MEFTDFSKTS FYQPLSQSIW DFGDLAAAEK SSLGFMELLD SQHNQQLHDS PHSFLVETLQ 60 PQTQPFSKLS SSDSTTLKAP PSATTAAKPV ASKVESLCSD HLLVNPPATP NSSSISSASS 120 EAVNEEKAKR EDEEEEEVEH EQEKSDTTKQ LKPKKNTQKR QREARVAFMT KSEVDHLEDG 180 YRWRKYGQKA VKNSPFPRSY YRCTTASCNV KKRVERSFRD PSTVVTTYEG QHTHISPLTS 240 RPISGGGYFG SSGVASNLGS FGFPMESSTL ISPQFQQLVH YHQQQQQQEL LSCFGGVGEY 300 VNSHANGYGD DERVKKSRGL VKDNGLLQDV VPSHMLKEE

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	8e-28	167	237	7	77	Probable WRKY transcription factor 4
2lex_A	8e-28	167	237	7	77	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00069	PBM	Transfer from AT2G47260	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676734888

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK117918	0.0	AK117918.1 Arabidopsis thaliana At2g47260 mRNA for putative WRKY-type DNA binding protein, complete cds, clone: RAFL19-10-C13.
GenBank	AY052647	0.0	AY052647.1 Arabidopsis thaliana WRKY transcription factor 23 (WRKY23) mRNA, complete cds.
GenBank	BT006238	0.0	BT006238.1 Arabidopsis thaliana At2g47260 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006397921.1	0.0	probable WRKY transcription factor 23
Swissprot	O22900	1e-168	WRK23_ARATH; WRKY transcription factor 23
TrEMBL	V4L6S1	0.0	V4L6S1_EUTSA; Uncharacterized protein
STRING	XP_006397921.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6152	26	47

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G47260.1	1e-143	WRKY DNA-binding protein 23

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guo D,Qin G EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signal Behav, 2016. 11(3): p. e1150404 [PMID:26914912] Prát T, et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. PLoS Genet., 2018. 14(1): p. e1007177 [PMID:29377885]