PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

TALE

Protein Properties

Length: 149aa MW: 17124.2 Da PI: 7.5129

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676730168	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	28.6	2.5e-09	92	126	21	55
HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS Homeobox 21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 k +yp++ ++ LA+ +gL+++q+ +WF N+R ++ 676730168 92 KWPYPTEGDKIALADATGLDQKQINNWFINQRKRH 126 569*****************************985 PP
2	ELK	31.5	3.8e-11	46	67	1	22
ELK 1 ELKhqLlrKYsgyLgsLkqEFs 22 +LK++LlrK++++++sLk EFs 676730168 46 DLKDRLLRKFGSRISSLKLEFS 67 69*******************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03789	9.0E-8	46	67	IPR005539	ELK domain
PROSITE profile	PS51213	9.83	46	66	IPR005539	ELK domain
SMART	SM01188	6.3E-5	46	67	IPR005539	ELK domain
PROSITE profile	PS50071	12.341	66	129	IPR001356	Homeobox domain
SuperFamily	SSF46689	2.91E-19	67	142	IPR009057	Homeodomain-like
SMART	SM00389	9.4E-13	68	133	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	3.4E-27	71	130	IPR009057	Homeodomain-like
CDD	cd00086	2.23E-11	75	130	No hit	No description
Pfam	PF05920	3.8E-17	86	125	IPR008422	Homeobox KN domain
PROSITE pattern	PS00027	0	104	127	IPR017970	Homeobox, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 149 aa Download sequence Send to blast
MEVTIHCGGF FTAALNNQDG AISSDEELSG GDEISQDGKQ RCEDRDLKDR LLRKFGSRIS 60 SLKLEFSKKK KKGKLPREAR QALLDWWNVH NKWPYPTEGD KIALADATGL DQKQINNWFI 120 NQRKRHWKPS DNMPFAMMDD SSGSFFTEE

Functional Description ? help Back to Top
Source	Description
UniProt	Plays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269\|PubMed:16798887}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676730168

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269\|PubMed:11311158, ECO:0000269\|PubMed:16798887}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024008598.1	7e-85	homeobox protein knotted-1-like 6
Swissprot	Q84JS6	4e-83	KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBL	A0A078JTL7	8e-85	A0A078JTL7_BRANA; BnaCnng70390D protein
TrEMBL	A0A0D3CCQ0	8e-85	A0A0D3CCQ0_BRAOL; Uncharacterized protein
STRING	Bo5g039530.1	1e-85	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM835	27	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G23380.2	1e-77	KNOTTED1-like homeobox gene 6

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Khan M, et al. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2166-86 [PMID:26417006]