PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bHLH

Protein Properties

Length: 243aa MW: 27562.7 Da PI: 6.5132

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676727278	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	15.8	2.6e-05	145	185	11	55
HHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 11 rRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 RR +iN+++ L++++P + k + a++L + ++Y++sLq 676727278 145 VRRGKINERLRCLQDIVPGC----YKSMGMATMLDEIINYVQSLQ 185 6****************8....366999************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:4.10.280.10	2.0E-12	130	195	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	11.928	134	184	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.9E-4	138	190	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.93E-12	144	202	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.81E-6	146	189	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006351	Biological Process	transcription, DNA-templated
GO:1902448	Biological Process	positive regulation of shade avoidance
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 243 aa Download sequence Send to blast
MANFESLSSE FQTIAMDIYS SLTQATDLNN NNSSSLQFQT LPPFSTCLDS LFLHRHQQQL 60 LDFPGKFSGS DNNFSSTSTL YHSDHNNVDE TKKRKALLQT LSSSENSGVS DNLNINTTET 120 GCSRRSKRLK KQKQEEEKER EVVHVRRGKI NERLRCLQDI VPGCYKSMGM ATMLDEIINY 180 VQSLQNQVEF LSMKLTAASS FYDFNSETDA VDSMQRAKAR EAVEMGRQTR DGSPVFHLST 240 WSL

Functional Description ? help Back to Top
Source	Description
UniProt	Positive regulator of brassinosteroid signaling. {ECO:0000269\|PubMed:12454087}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676727278

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by brassinosteroid, auxin, ethylene and cytokinin, and repressed by abscisic acid. Insensitive to gibberellic acid. {ECO:0000269\|PubMed:12454087}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488579	1e-128	AF488579.1 Arabidopsis thaliana clone bHLH044 putative bHLH transcription factor mRNA, partial sequence.
GenBank	AK117269	1e-128	AK117269.1 Arabidopsis thaliana At1g18400 mRNA for putative bHLH transcription factor (bHLH044), complete cds, clone: RAFL16-82-F22.
GenBank	AY138253	1e-128	AY138253.1 Arabidopsis thaliana putative bHLH transcription factor (BEE1) mRNA, complete cds.
GenBank	BT005268	1e-128	BT005268.1 Arabidopsis thaliana At1g18400 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018482284.1	1e-145	PREDICTED: transcription factor BEE 1
Swissprot	Q8GZ13	1e-111	BEE1_ARATH; Transcription factor BEE 1
TrEMBL	A0A3P5YFI0	1e-142	A0A3P5YFI0_BRACM; Uncharacterized protein
STRING	Bo5g025360.1	1e-132	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2997	27	65

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G18400.1	1e-101	BR enhanced expression 1

Publications ? help Back to Top
Petridis A,Döll S,Nichelmann L,Bilger W,Mock HP Arabidopsis thaliana G2-LIKE FLAVONOID REGULATOR and BRASSINOSTEROID ENHANCED EXPRESSION1 are low-temperature regulators of flavonoid accumulation. New Phytol., 2016. 211(3): p. 912-25 [PMID:27125220]