PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

ZF-HD

Protein Properties

Length: 250aa MW: 27108.3 Da PI: 7.9214

Description

ZF-HD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676720860	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	ZF-HD_dimer	106.1	2.1e-33	20	78	2	59
ZF-HD_dimer 2 ekvrYkeClkNhAaslGghavDGCgEfmpsegee.gtaaalkCaACgCHRnFHRrevee 59 ++v YkeClkNhAa+lGgha+DGCgEfmp+++++ +++++l+CaACgCHRnFHRr++++ 676720860 20 MGVCYKECLKNHAANLGGHALDGCGEFMPTPTATpTDPSSLRCAACGCHRNFHRRDPSD 78 5789***************************99******************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD125774	7.0E-19	22	75	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
Pfam	PF04770	1.4E-27	22	75	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
TIGRFAMs	TIGR01566	3.3E-30	24	75	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
PROSITE profile	PS51523	27.049	24	75	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
Gene3D	G3DSA:1.10.10.60	1.4E-26	142	211	IPR009057	Homeodomain-like
SuperFamily	SSF46689	7.45E-17	143	210	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01565	1.9E-28	152	209	IPR006455	Homeodomain, ZF-HD class

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0042803	Molecular Function	protein homodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 250 aa Download sequence Send to blast
MDLSSKHKQT LTNSPVAGEM GVCYKECLKN HAANLGGHAL DGCGEFMPTP TATPTDPSSL 60 RCAACGCHRN FHRRDPSDHL GSFLPSHPTL SPSGTESPPS QSLHHVASPV PCSYYTSAPH 120 HVLLSLSSGF PGPSDQDPTA VRSENSSKGA MRKRTRTKFT PEQKVKMRAF AEKAGWRING 180 CDDMSVRDFC SEIGIERGVL KVWMHNNKYS HLNGKNREIV SMDHRLLCLN TQSCNNGGEE 240 GDNADGSSSS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wh7_A	1e-20	153	210	18	75	ZF-HD homeobox family protein
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the up-regulation of several stress-inducible genes. Acts as a transcriptional activator by interacting with MED25 and NAC proteins. Involved in increased drought tolerance. {ECO:0000269\|PubMed:16428600, ECO:0000269\|PubMed:17233795}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676720860

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by abscisic acid and by drought and salt stress. Not induced by cold. {ECO:0000269\|PubMed:17233795}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC189353	0.0	AC189353.2 Brassica rapa subsp. pekinensis cultivar Inbred line 'Chiifu' clone KBrB043L15, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013666218.1	1e-160	zinc-finger homeodomain protein 11
Swissprot	Q9SEZ1	1e-132	ZHD11_ARATH; Zinc-finger homeodomain protein 11
TrEMBL	A0A078GSU0	1e-159	A0A078GSU0_BRANA; BnaC02g19350D protein
STRING	Bo2g064220.1	1e-159	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5166	25	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69600.1	1e-122	zinc finger homeodomain 1

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444]