PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bHLH

Protein Properties

Length: 226aa MW: 25324.1 Da PI: 10.3675

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676719304	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26.4	1.2e-08	134	174	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L 676719304 134 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 174 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	125	174	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.0E-14	126	184	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.26E-14	129	184	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.3E-14	131	180	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	6.2E-6	135	174	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	3.81E-6	148	179	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010500	Biological Process	transmitting tissue development
GO:0048462	Biological Process	carpel formation
GO:0080126	Biological Process	ovary septum development
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 226 aa Download sequence Send to blast
MDNSDILMNM MMLQMEKFPD HFSNPNPSSH NIMMPSEPNT QPFFFNHNQT HLPLVDPTIT 60 HHHRPGLNFR YAPSTSSFLP DKRGGGGDNA NMAAMREMIF RIAVMQPIHI DPESVKPPKR 120 KNVRISKDPQ SVAARHRRER ISERIRILQR LVPGGTKMDT ASMLDEAIHY VKFLKKQVQS 180 LEEHAVVNGG GMTSAPPVVG GGYGGKGCGT MRSDHHQMLG NAQILR

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676719304

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK175679	1e-171	AK175679.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor (bHLH037), complete cds, clone: RAFL22-18-N14.
GenBank	AK175912	1e-171	AK175912.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor (bHLH037), complete cds, clone: RAFL22-57-C09.
GenBank	AL132976	1e-171	AL132976.2 Arabidopsis thaliana DNA chromosome 3, BAC clone F11C1.
GenBank	BT010607	1e-171	BT010607.1 Arabidopsis thaliana At3g50330 gene, complete cds.
GenBank	CP002686	1e-171	CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_018438373.1	1e-133	PREDICTED: transcription factor HEC2-like
Swissprot	Q9SND4	1e-107	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A078FTA1	1e-127	A0A078FTA1_BRANA; BnaC08g21730D protein
TrEMBL	A0A0D3DRW3	1e-127	A0A0D3DRW3_BRAOL; Uncharacterized protein
TrEMBL	A0A3N6RDA5	1e-127	A0A3N6RDA5_BRACR; Uncharacterized protein
TrEMBL	A0A3P6FGF0	1e-127	A0A3P6FGF0_BRAOL; Uncharacterized protein
STRING	Bo8g079710.1	1e-127	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50330.1	1e-100	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]