PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

bHLH

Protein Properties

Length: 288aa MW: 32562 Da PI: 4.3824

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676711650	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.2	4e-10	139	186	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rEr RR+++N++f L ++l + + +K +K +iL A++ +++L 676711650 139 TKACRERLRREKLNERFMDLSSVLEPG---RTPKTDKPAILDDAIRVLNQL 186 5678********************8...8***************999 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.697	135	186	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.70E-8	139	189	No hit	No description
Pfam	PF00010	1.9E-7	139	186	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.4E-10	141	192	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.13E-12	141	208	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.0E-11	143	208	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 288 aa Download sequence Send to blast
MYPSLDDEDF VADLFCFDQS NGAELDDYTQ FGVNLQHDQE DTFPDFGSYG VNLQNETQEV 60 FSIGGGQLDF TSYSGVLTQE TEQFRSFGGK NDCGVVQEDE VDVNSGSSGG GVKQEQEHID 120 EDCSRKRGRT GSCSRPGGTK ACRERLRREK LNERFMDLSS VLEPGRTPKT DKPAILDDAI 180 RVLNQLRDEA HELEETNQKL LDEIKSLKAE KNELREEKLA LKAEKEKTEQ QLKSMMVPPT 240 GYMPQMPAPF NQNKMAVYPS YGYMPMWHYL PQSVCDTSRD QELRPPAA

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00102	PBM	Transfer from AT4G14410	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676711650

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009124106.1	0.0	PREDICTED: transcription factor bHLH104 isoform X2
Swissprot	Q8L467	1e-170	BH104_ARATH; Transcription factor bHLH104
TrEMBL	A0A078FEH2	0.0	A0A078FEH2_BRANA; BnaC04g28710D protein
STRING	Bra041033.1-P	0.0	(Brassica rapa)
STRING	Bo4g126940.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4026	26	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.1	1e-134	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]