PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 496218
Common NameARALYDRAFT_496218
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HD-ZIP
Protein Properties Length: 845aa    MW: 92485.2 Da    PI: 5.9515
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
496218genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox56.45e-182583357
              --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
  Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
              k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR ++k+
    496218 25 KYVRYTAEQVEALERVYAECPKPSSLRRQQLIRECsilaNIEPKQIKVWFQNRRCRDKQ 83
              56789***************************************************996 PP
2START153.12.4e-481623672202
             HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEEEEXXTTXX CS
   START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlmvaelqals 102
             +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s+ +sg a+ra+g+v  +++   +e+l+d++ W +++++ e+      g  g+++l +++++a++
  496218 162 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQRCSGVAARACGLVSLEPM-KIAEILKDRPSWFRDCRSLEVFTLFPAGngGTIELVYMQTYAPT 263
             7899******************************************************.7777777777*******9998888887778************** PP

             -SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTX CS
   START 103 plvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaegaktwvatlq 201
             +l+p Rdf+++Ry+ +l  g++v++++S++     p+    s++vRae+l Sg+li+p+++g+s +++v+h +l++++++ +lr+l++s+ + ++k++ ++l+
  496218 264 TLAPaRDFWTLRYTTSLDNGSFVVCERSLSGSGAGPNaasASQFVRAEMLSSGYLIRPCDGGGSIIHIVDHLNLEAWSVPDVLRPLYESSKVVAQKMTISALR 366
             ******************************999999989999********************************************************99998 PP

             X CS
   START 202 r 202
             +
  496218 367 Y 367
             7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.3052084IPR001356Homeobox domain
SuperFamilySSF466891.11E-162187IPR009057Homeodomain-like
SMARTSM003892.0E-162288IPR001356Homeobox domain
CDDcd000866.24E-162585No hitNo description
PfamPF000461.3E-152683IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.603.0E-182780IPR009057Homeodomain-like
CDDcd146863.26E-677116No hitNo description
Gene3DG3DSA:1.20.5.1707.9E-481130No hitNo description
PROSITE profilePS5084827.103152380IPR002913START domain
CDDcd088751.22E-66156372No hitNo description
Gene3DG3DSA:3.30.530.202.0E-19160365IPR023393START-like domain
SuperFamilySSF559611.3E-34161373No hitNo description
SMARTSM002343.5E-38161371IPR002913START domain
PfamPF018525.2E-46162368IPR002913START domain
PfamPF086703.8E-49696843IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 845 aa     Download sequence    Send to blast
MEMAVANHRE RSSDSMNRHL DSSGKYVRYT AEQVEALERV YAECPKPSSL RRQQLIRECS  60
ILANIEPKQI KVWFQNRRCR DKQRKEASRL QSVNRKLSAM NKLLMEENDR LQKQVSQLVC  120
ENGYMKQQLT TVVCNDPSCE SVVTTPQHSL RDASSPAGLI SIAEETLAEF LSKATGTAVD  180
WVQMPGMKPG PDSVGIFAIS QRCSGVAARA CGLVSLEPMK IAEILKDRPS WFRDCRSLEV  240
FTLFPAGNGG TIELVYMQTY APTTLAPARD FWTLRYTTSL DNGSFVVCER SLSGSGAGPN  300
AASASQFVRA EMLSSGYLIR PCDGGGSIIH IVDHLNLEAW SVPDVLRPLY ESSKVVAQKM  360
TISALRYIRQ LAQETNGEVV YGLGRQPAVL RTFSQRLSRG FNDAVNGFGD DGWSTMHCDG  420
AEDIIVAINS TKHLNNISNS LSFLGGVLCA KASMLLQNVP PAVLIRFLRE HRSEWADFNV  480
DAYSAATLKA GTFAYPGMRP TRFTGSQIIM PLGHTIEHEE MLEVVRLEGH SLAQEDAFMS  540
RDVHLLQICT GIDENAVGAC SELIFAPINE MFPDDAPLVP SGFRVIPVDA KTGDAQDLLT  600
ANHRTLDLTS SLEVGPSPEN ASGNSSSSSS SSRCILTIAF QFPFENNLQE NVAGMACQYV  660
RSVISSVQRV AMAVSPSGIS PSLGSKLSPG SPEAVTLAQW ISQSYSHHLG SELMTIDSLG  720
SNDSVLKLLW DHQDAILCCS LKPQPVFMFA NQAGLDMLET TLVALQDITL EKIFDESGRK  780
ALCSDFAKLM QQGFACLPSG ICVSTMGRHV SYEQAVAWKV FAASEDNNNN LHCLAFSFVN  840
WSFV*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap496218
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF1889940.0AF188994.1 Arabidopsis thaliana homeodomain-leucine zipper protein interfascicular fiberless 1 (IFL1) mRNA, complete cds.
GenBankAF2335920.0AF233592.1 Arabidopsis thaliana REVOLUTA mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020885782.10.0homeobox-leucine zipper protein REVOLUTA
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLD7MTW70.0D7MTW7_ARALL; Uncharacterized protein
STRINGfgenesh2_kg.8__2034__AT5G60690.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM47792754
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]