PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ZF-HD

Protein Properties

Length: 328aa MW: 35641.2 Da PI: 8.6342

Description

ZF-HD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
494014	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	ZF-HD_dimer	107.3	8.6e-34	50	106	4	59
ZF-HD_dimer 4 vrYkeClkNhAaslGghavDGCgEfmpsegee.gtaaalkCaACgCHRnFHRrevee 59 ++YkeClkNhAa+lGgha+DGCgEfmps+++ +++++lkCaACgCHRnFHRr++++ 494014 50 FTYKECLKNHAAALGGHALDGCGEFMPSPSSIsSDPTSLKCAACGCHRNFHRRDPDN 106 68************************9999899****************9886 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04770	6.7E-28	51	104	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
TIGRFAMs	TIGR01566	1.8E-31	51	103	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
ProDom	PD125774	4.0E-17	52	119	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
PROSITE profile	PS51523	27.629	52	103	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
SuperFamily	SSF46689	1.28E-18	182	256	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	1.1E-28	184	256	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01565	2.7E-25	195	252	IPR006455	Homeodomain, ZF-HD class

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009739	Biological Process	response to gibberellin
GO:0003677	Molecular Function	DNA binding
GO:0042803	Molecular Function	protein homodimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 328 aa Download sequence Send to blast
MDMTPTITTT TTTPKSPEPE SETPTRIQPA KPISFSNGII KRHHHHPLLF TYKECLKNHA 60 AALGGHALDG CGEFMPSPSS ISSDPTSLKC AACGCHRNFH RRDPDNNNDS SPIHPPPSTA 120 VEYQPHHRHH PPPPLPPPPP RSPNSASPPP ISSSYMLLSL SGTNNNNNNL ASFSDLNFPG 180 GNNHHHHQHT LHGSRKRFRT KFSQFQKEKM HEFAERLGWK MQKRDEDDVR DFCRQIGVDK 240 SVLKVWMHNN KNTFNRRDLA GNEIRKIDNG GGNHTPILTG EINNNNNGHH GGGGGELHHS 300 VSSGGGGGFD SDSGGANGGN VNGSSSS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wh7_A	2e-20	194	253	16	75	ZF-HD homeobox family protein
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Putative transcription factor. Probably involved in establishing polarity during leaf development through the gibberellic acid (GA) signaling pathway. {ECO:0000269\|PubMed:17387478}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00536	DAP	Transfer from AT5G39760	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	494014

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By gibberellic acid (GA). {ECO:0000269\|PubMed:17387478}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB016876	0.0	AB016876.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MKM21.
GenBank	AK228484	0.0	AK228484.1 Arabidopsis thaliana mRNA for hypothetical protein, complete cds, clone: RAFL15-09-C01.
GenBank	AY091034	0.0	AY091034.1 Arabidopsis thaliana unknown protein (At5g39760) mRNA, complete cds.
GenBank	AY117347	0.0	AY117347.1 Arabidopsis thaliana unknown protein (At5g39760) mRNA, complete cds.
GenBank	CP002688	0.0	CP002688.1 Arabidopsis thaliana chromosome 5 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020872961.1	0.0	zinc-finger homeodomain protein 10
Swissprot	Q9FIW9	1e-130	ZHD10_ARATH; Zinc-finger homeodomain protein 10
TrEMBL	D7MJI5	0.0	D7MJI5_ARALL; Uncharacterized protein
STRING	fgenesh2_kg.7__3447__AT5G39760.1	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2220	25	75

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G39760.1	1e-102	homeobox protein 23

Link Out ? help Back to Top
Phytozome	494014
Entrez Gene	9306832

Publications ? help Back to Top
Kazama D,Kurusu T,Mitsuda N,Ohme-Takagi M,Tada Y Involvement of elevated proline accumulation in enhanced osmotic stress tolerance in Arabidopsis conferred by chimeric repressor gene silencing technology. Plant Signal Behav, 2014. 9(3): p. e28211 [PMID:24614501] Ribone PA,Capella M,Chan RL Functional characterization of the homeodomain leucine zipper I transcription factor AtHB13 reveals a crucial role in Arabidopsis development. J. Exp. Bot., 2015. 66(19): p. 5929-43 [PMID:26136262] Kazama D, et al. Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis. Plants (Basel), 2013. 2(4): p. 769-85 [PMID:27137403]