PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 278aa MW: 31182.7 Da PI: 4.5743

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
493462	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.8	2.6e-10	128	175	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rEr RR+++N++f L ++l + + +K +K +iL A++ +++L 493462 128 TKACRERMRREKLNERFMDLSSVLEPG---RTPKTDKPAILDDAIRILNQL 175 5678********************8...8**************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.551	124	175	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.4E-7	128	175	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.18E-8	128	178	No hit	No description
SuperFamily	SSF47459	7.33E-13	130	198	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	9.5E-10	130	181	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.5E-11	132	197	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 278 aa Download sequence Send to blast
MDVDLFVHDD SCSNGAELDD YTQFGVNLQP DQEDTFPDFA SYGVNLQQDP EEVFSIGAAQ 60 LDLSSYNGVL SQEPEHVGQK DCGIVQEDEV EINSGSSGGA VKQEQEHLDD DCSRKRARTG 120 SCSRGGGTKA CRERMRREKL NERFMDLSSV LEPGRTPKTD KPAILDDAIR ILNQLRDEAH 180 KLEETNQKLL EEIKSLKAEK NELREEKLVL KVDKEKTEQQ LKSMTVPSSG LMPQIPAAFS 240 HNKMAVYPSY GYMPMWHYMP QSVRDTSRDQ ELRPPAA*

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00102	PBM	Transfer from AT4G14410	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	493462

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF488628	0.0	AF488628.1 Arabidopsis thaliana clone bHLH104 putative bHLH transcription factor mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020872680.1	0.0	transcription factor bHLH104
Refseq	XP_020872681.1	0.0	transcription factor bHLH104
Swissprot	Q8L467	1e-179	BH104_ARATH; Transcription factor bHLH104
TrEMBL	D7MH23	0.0	D7MH23_ARALL; Basic helix-loop-helix family protein
STRING	fgenesh2_kg.7__2895__AT4G14410.2	0.0	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM4026	26	53

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.2	1e-175	bHLH family protein

Link Out ? help Back to Top
Phytozome	493462
Entrez Gene	9304357

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]