 |
Plant Transcription
Factor Database
|
Transcription Factor Information
|
Basic
Information? help
Back to Top |
| TF ID |
491205 |
| Common Name | ARALYDRAFT_491205 |
| Organism |
|
| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
|
| Family |
bHLH |
| Protein Properties |
Length: 334aa MW: 37399.1 Da PI: 5.4991 |
| Description |
bHLH family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| 491205 | genome | JGI | View CDS |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | HLH | 30.6 | 6.1e-10 | 179 | 226 | 4 | 55 |
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
+h+++Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq
491205 179 SHSIAERVRREKISERMKFLQDLVPGC----DKITGKAGMLDEIINYVQSLQ 226
8*************************9....899*****************9 PP
|
| Gene Ontology ? help Back to Top |
| GO Term |
GO Category |
GO Description |
| GO:0006351 | Biological Process | transcription, DNA-templated |
| GO:0009637 | Biological Process | response to blue light |
| GO:0009911 | Biological Process | positive regulation of flower development |
| GO:0005634 | Cellular Component | nucleus |
| GO:0003677 | Molecular Function | DNA binding |
| GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
| GO:0046983 | Molecular Function | protein dimerization activity |
| Sequence ? help Back to Top |
| Protein Sequence Length: 334 aa
Download sequence Send
to blast |
MNGAIGGDLL LNCTDMSVLE RQRAHLKYFN PSFDSPLAGF FADSSMINGG EMDGYLATAG 60
LNLPMIYGET TVEGDPRMSI SPETTLGTGN FKKRKFDTET KDRNEKKKKM NREEVTEEEE 120
EKSKITELNN GSPKSIKKMK NKAKKEENNC SNDSSKVTKE LEKTDYIHVR ARRGQATDSH 180
SIAERVRREK ISERMKFLQD LVPGCDKITG KAGMLDEIIN YVQSLQRQIE FLSMKLAVVN 240
PRPDFDMDDI FDKEVIVSTP MTVVPSPEMV HSGYSHEMVN SGYSNEMVNS GYHHVNPMQQ 300
AETSSDPLSC FNNGQAPSMW DSYVQNLYGS LGV*
|
| Nucleic Localization
Signal ? help
Back to Top |
 |
| No. |
Start |
End |
Sequence |
| 1 | 92 | 108 | KRKFDTETKDRNEKKKK |
| Functional Description ? help
Back to Top |
| Source |
Description |
| UniProt | Transcription factor that binds DNA to G box 5'-CACGTG-3' and, to a lower extent, to E-box 5'-CANNTG-3' in vitro. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. {ECO:0000269|PubMed:18988809, ECO:0000269|PubMed:24130508}. |
| Regulation -- Description ? help
Back to Top |
| Source |
Description |
| UniProt | INDUCTION: Accumulates strongly in response to blue light due to reduced preventing 26S proteasome-mediated degradation in an ADO1/ZTL and ADO2/LKP2 dependent manner, but levels decrease in the absence of blue light via 26S proteasome degradation (at protein level). {ECO:0000269|PubMed:24101505}. |
| Annotation --
Nucleotide ? help
Back to Top |
| Source |
Hit ID |
E-value |
Description |
| GenBank | AF488596 | 0.0 | AF488596.1 Arabidopsis thaliana clone bHLH063 putative bHLH transcription factor mRNA, complete cds. |
| GenBank | AK117846 | 0.0 | AK117846.1 Arabidopsis thaliana At4g34530 mRNA for putative bHLH transcription factor (bHLH063), complete cds, clone: RAFL18-04-K08. |
| GenBank | BT005313 | 0.0 | BT005313.1 Arabidopsis thaliana At4g34530 mRNA, complete cds. |
| Best hit in Arabidopsis thaliana ? help
Back to Top |
| Hit ID |
E-value |
Description |
| AT4G34530.1 | 0.0 | cryptochrome-interacting basic-helix-loop-helix 1 |
| Publications
? help Back to Top |
- Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
Differentiation, 2010. 80(1): p. 1-8
[PMID:20219281] - Yang D,Zhao W,Meng Y,Li H,Liu B
A CIB1-LIKE transcription factor GmCIL10 from soybean positively regulates plant flowering.
Sci China Life Sci, 2015. 58(3): p. 261-9
[PMID:25651969] - Katsura Y, et al.
An optogenetic system for interrogating the temporal dynamics of Akt.
Sci Rep, 2015. 5: p. 14589
[PMID:26423353] - Taslimi A, et al.
Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase.
Nat. Chem. Biol., 2016. 12(6): p. 425-30
[PMID:27065233] - Liu Q, et al.
The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases.
Plant Cell Physiol., 2016. 57(10): p. 2175-2186
[PMID:27516416] - Pathak GP, et al.
Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2.
Nucleic Acids Res., 2017. 45(20): p. e167
[PMID:28431041] - Duan L, et al.
Understanding CRY2 interactions for optical control of intracellular signaling.
Nat Commun, 2017. 8(1): p. 547
[PMID:28916751] - Quejada JR, et al.
Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1.
Nucleic Acids Res., 2017. 45(20): p. e172
[PMID:29040770] - Liu Y, et al.
CIB1 and CO interact to mediate CRY2-dependent regulation of flowering.
EMBO Rep., 2019.
[PMID:30126927]
|
