PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 487987
Common NameARALYDRAFT_487987
Organism
Arabidopsis lyrata
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family MYB
Protein Properties Length: 961aa    MW: 107908 Da    PI: 5.3694
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
487987genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding58.41.6e-183278148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     rg WT+eEde+l +av+ + g++Wk+Ia+++   Rt+ qc +rwqk+l
           487987 32 RGQWTAEEDEILRKAVHSFKGKNWKKIAEYFK-DRTDVQCLHRWQKVL 78
                     89*****************************9.************986 PP
2Myb_DNA-binding62.67.8e-2084130148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+WT+eEde +v++++++G++ W+tIar ++ gR +kqc++rw+++l
           487987  84 KGPWTKEEDEMIVQLIEKYGPKKWSTIARFLP-GRIGKQCRERWHNHL 130
                      79******************************.*************97 PP
3Myb_DNA-binding431e-13136178145
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 
                      + +WT+eE++ l++a++ +G++ W+   + ++ gR+++ +k++w+
           487987 136 KEAWTQEEELVLIRAHQIYGNR-WAELTKFLP-GRSDNGIKNHWH 178
                      579*******************.*********.***********8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129419.2942778IPR017930Myb domain
SuperFamilySSF466892.08E-152984IPR009057Homeodomain-like
SMARTSM007171.2E-153180IPR001005SANT/Myb domain
PfamPF002492.1E-163278IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.0E-223386IPR009057Homeodomain-like
CDDcd001673.93E-143578No hitNo description
PROSITE profilePS5129432.60979134IPR017930Myb domain
SuperFamilySSF466891.09E-3181177IPR009057Homeodomain-like
SMARTSM007173.5E-1983132IPR001005SANT/Myb domain
PfamPF002491.1E-1784130IPR001005SANT/Myb domain
CDDcd001674.80E-1786130No hitNo description
Gene3DG3DSA:1.10.10.601.9E-2787134IPR009057Homeodomain-like
PROSITE profilePS5129418.094135185IPR017930Myb domain
SMARTSM007171.5E-12135183IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.6E-19135185IPR009057Homeodomain-like
PfamPF002499.6E-12136178IPR001005SANT/Myb domain
CDDcd001678.89E-10138178No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032875Biological Processregulation of DNA endoreduplication
GO:0003677Molecular FunctionDNA binding
GO:0003713Molecular Functiontranscription coactivator activity
Sequence ? help Back to Top
Protein Sequence    Length: 961 aa     Download sequence    Send to blast
MESESSTISA PHEGIPKSRH GRTSGPARRS TRGQWTAEED EILRKAVHSF KGKNWKKIAE  60
YFKDRTDVQC LHRWQKVLNP ELVKGPWTKE EDEMIVQLIE KYGPKKWSTI ARFLPGRIGK  120
QCRERWHNHL NPAINKEAWT QEEELVLIRA HQIYGNRWAE LTKFLPGRSD NGIKNHWHSS  180
VKKKLDSYMS SGILDQYQAM PLAPYERSST LQSSFMQSNI DGNGCLNGQE ENEIDSRQNS  240
SMVGCSLSAR DFQNGAINMG HDFHPCGNSQ ENEQTVYHSD QYFYPELEDI SVSISEVSYD  300
MEDCSQFPDH NVSTSPSQDY QFDFQELSDI SLEIRHDMSE IPMPYMKESK ESTLGAPNST  360
LNIDVATYTN SANVLTPETE CCRVLFPDQE SEGHSVSRSL TQEPNQVDQA DRRDPILCAS  420
ASDRQISEAT KSPTQSSSSR FIATAASGKE TLRPAPLIIS PDKYSKKSSG LICHPFEAVP  480
KCTTNGNGSF ICIDDSSIST CVDEGTNNSS EEDQSYHVSD PKKLVPVNDF ASLAEDRPHS  540
LPKHEPNMTS EQHHEDTGAS SSLGFPSLDL PVFSCDLLQS KNDPLHDYSP LGIRKLLMST  600
MTCMSPLRLW ESPTEKKTLV GAQSILRKRT RDLLTPLSEK RSDKKLEIDI AASLAKDFSR  660
LDVMFDESEN RQSIFGNSTG VIHGDRENHF QILSGEGEEN WKPSSLFSHR MPEETMHIRK  720
SLEKADQTCM EANVREKDDS EQDVENVEFF SGFLSDHNTG KPVLSSPGQS VTKAEKTQVS  780
TPRNQLNRTL MATSNKEHHS PSSVCLVINS PSRARSKEGH LVDNGTSNEN FSIFCGTPFR  840
RGLESPSAWK SPFYINSLLP SPRFDTDITI EDMGYIFSPG ERSIGVMTQR NEHTSAFAAF  900
ADAMEVSISP TNDNARQKKE LDKENNDPLL AERRVLDFND CESPIKTTEE VSSYLLKGCR  960
*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C7e-68321856159MYB PROTO-ONCOGENE PROTEIN
1h89_C7e-68321856159MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669, PubMed:25806785). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:21862669, ECO:0000269|PubMed:25806785}.; FUNCTION: Involved in transcription regulation during induced endoreduplication at the powdery mildew (e.g. G.orontii) infection site, thus promoting G.orontii growth and reproduction. {ECO:0000269|PubMed:20018666}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00505DAPTransfer from AT5G11510Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap487987
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Slightly induced by salicylic acid (SA) (PubMed:16463103). Expressed in a cell cycle-dependent manner, with highest levels 2 hours before the peak of mitotic index in cells synchronized by aphidicolin. Activated by CYCB1 (PubMed:17287251). Accumulates at powdery mildew (e.g. G.orontii) infected cells. {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:17287251}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF3719750.0AF371975.2 Arabidopsis thaliana putative c-myb-like transcription factor MYB3R-4 (MYB3R4) mRNA, complete cds.
GenBankAY5196500.0AY519650.1 Arabidopsis thaliana MYB transcription factor (At5g11510) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020877979.10.0transcription factor MYB3R-4
RefseqXP_020877980.10.0transcription factor MYB3R-4
RefseqXP_020877981.10.0transcription factor MYB3R-4
RefseqXP_020877982.10.0transcription factor MYB3R-4
RefseqXP_020877983.10.0transcription factor MYB3R-4
RefseqXP_020877984.10.0transcription factor MYB3R-4
SwissprotQ94FL90.0MB3R4_ARATH; Transcription factor MYB3R-4
TrEMBLD7M3R40.0D7M3R4_ARALL; Uncharacterized protein
STRINGfgenesh2_kg.6__1121__AT5G11510.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM132131828
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G11510.10.0myb domain protein 3r-4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Saito T, et al.
    Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana.
    Plant Signal Behav, 2015. 10(3): p. e990817
    [PMID:25806785]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  4. Chen P, et al.
    Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage.
    Nat Commun, 2017. 8(1): p. 635
    [PMID:28935922]